Hippocampal rhythmopathies in temporal lobe epilepsy
Transcrição
Hippocampal rhythmopathies in temporal lobe epilepsy
Invitation to Seminar Talk Hippocampal rhythmopathies in temporal lobe epilepsy Liset Menéndez de la Prida (Department of Functional and Systems Neurobiology, Instituto Cajal - CSIC) Host: Jozsef Csicsvari Natural rhythms of the hippocampus, including theta (4-12 Hz), gamma (40-120 Hz) and high-frequency oscillations (150-200 Hz), play different roles in orchestrating neuronal firing during different cognitive demands. In temporal lobe epilepsy (TLE), the most frequent form of refractory epilepsy in human, the hippocampus produces distorted oscillations that presumably reflect the underlying alterations of circuits and neurons. Are there common principles in the cellular processes responsible for theta, gamma and ripple oscillations in the normal and the epileptic hippocampus? In this talk I will discuss on our recent data aimed to identify the rules governing hippocampal rhythmopathies in TLE and their relationship with the physiological hippocampal function. We will examine different in vitro and in vivo data from normal and epileptic rats, as well as human data, obtained with a combination of techniques including multi-site recordings and single-cell electrophysiology. Thursday, March 13th 2014, 11:00am Seminar Room, Lab Building East, Ground Floor This invitation is valid as a ticket for the IST Shuttle from and to Heiligenstadt Station. Please find a schedule of the IST Shuttle on our webpage (note that the IST Shuttle times are highlighted in dark green): http://ist.ac.at/fileadmin/user_upload/pdfs/IST_shuttle_bus.pdf. The IST Shuttle bus is marked IST Shuttle (#242) and has the Institute Logo printed on the side. Institute of Science and Technology Austria | Am Campus 1 | 3400 Klosterneuburg www.ist.ac.at