Maria Jose Soares Mendes Giannini Position: Full Professor

CURRICULUM SUMMARY
PERSONAL DATA
Name: Maria Jose Soares Mendes Giannini
Position: Full Professor – Pharmacy School, São Paulo State University - UNESP, Araraquara, SP, Brazil.
E-mail: MENDES GIANNINI, M.J.S.; Mendes-Giannini, Maria José Soares; Soares Mendes MJ;Gianini MJ;MendesGiannini, Maria José S.;MENDES-GIANNINI, M. J. S.;SOARES MENDES GIANINNI, MARIA JOSÉ;Maria José
Soares Mendes-Giannini;MENDES-GIANNINI MJ;Mendes-Giannini MJ;MENDES-GIANNINI, MARIA J.
S.;MENDES-GIANNINI, MARIA;SOARES MENDES-GIANNINI, M. J.
EDUCATION
Pharmacist, University of São Paulo, USP, in 1976.
Master in Science – Microbiology and Immunology, Institute of Biosciences, University of São Paulo, São Paulo, in 1982.
PhD in Sciences, Institute of Biosciences, University of São Paulo, São Paulo, in 1989.
Postdoctoral: Isolation and identification of Paracoccididoides enzymes-held at the Biotechnology Institute – UFRGSunder the supervision of Professor Dr. Aoi Masuda, 1994.
LIST OF SELECTED PUBLISHED ARTICLES (see the complete CV in the LATTES CV Platform of CNPq:
www.cnpq.br - Plataforma LATTES – Link to scholar google:
http://scholar.google.com.br/citations?user=3AGyxVAAAAAJ&hl=en-h citations (2628) H index 29.
http://www.researcherid.com/rid/C-5387-2012 - ISI citations (1337) H index 21.
1-Costa-Orlandi CB, Sardi JC, Santos CT, Fusco-Almeida AM, Mendes-Giannini MJ. In vitro characterization of
Trichophyton rubrum and T. mentagrophytes biofilms. Biofouling. 2014 Jul;30(6):719-27. doi:
10.1080/08927014.2014.919282. Epub 2014 May 23. PMID: 24856309.
2-Teodoro VL, Gullo FP, Sardi Jde C, Torres EM, Fusco-Almeida AM, Mendes-Giannini MJ. Environmental isolation,
biochemical identification, and antifungal drug susceptibility of Cryptococcus species. Rev Soc Bras Med Trop. 2013
Nov-Dec;46(6):759-64. doi: 10.1590/0037-8682-0025-2013.
3-Sardi Jde C, Pitangui Nde S, Rodríguez-Arellanes G, Taylor ML, Fusco-Almeida AM, Mendes-Giannini MJ. Highlights
in pathogenic fungal biofilms. Revista Iberoamericana de Micología, v. 31, p. 22-29, 2014.
4-PAULA E SILVA, A. C. ; OLIVEIRA, H.C. ; SILVA, J.F. ; SCORZONI, L. ; FUSCO-ALMEIDA, A.M. ; MendesGiannini, Maria José Soares . Microplate alamarBlue Assay for Paracoccidioides Susceptibility Testing. Journal of
Clinical Microbiology (Print), v. 51, p. 1250-1252, 2013.
5-SARDI, J.J.O. ; SCORZONI, L. ; BERNARDI, T. ; FUSCO-ALMEIDA, A.M. ; Mendes-Giannini, Maria José Soares .
Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic
options. Journal of Medical Microbiology, v. 62, p. 10-24, 2013.
6-PIRES, R.H. ; SILVA, J.F. ; MARTINS, C.H.G. ; FUSCO-ALMEIDA, A.M. ; SOARES, C.P. ; Mendes-Giannini,
M.J.S. . Effectiveness of Disinfectants Used in Hemodialysis against both Candida orthopsilosis and C. parapsilosis Sensu
Stricto Biofilms. Antimicrobial Agents and Chemotherapy (Print), v. 57, p. 2417, 2013.
7-SCORZONI, L. ; LUCAS, M. P. ; MESA-ARANGO, A.C. ; FUSCO-ALMEIDA, A.M. ; LOZANO, E. ; CUENCAESTRELLA, M. ; ZARAGOZA, O. ; Mendes-Giannini, M.J.S. Antifungal Efficacy during Candida krusei Infection in
Non-Conventional Models Correlates with the Yeast In Vitro Susceptibility Profile . Plos One, v. 8, p. e60047, 2013.
8-SILVA, J.F. ; OLIVEIRA, H.C. ; MARCOS, C.M. ; SILVA, R.A.M. ; COSTA, T.A. ; CALICH, V.L.G. ; FUSCOALMEIDA, A.M. ; Mendes-Giannini, M.J.S. Paracoccidoides brasiliensis 30 kDa Adhesin: Identification as a 14-3-3
Protein, Cloning and Subcellular Localization in Infection Models. Plos One, v. 8, p. e62533, 2013.
9-RODRIGUEZ-ARELLANES, G. ; NASCIMENTO DE SOUSA, C. ; DE MEDEIROS-MUNIZ, M. ; RAMIREZ, J. A. ;
PIZZINI, C. V. ; DE ABREU-ALMEIDA, M. ; EVANGELISTA DE OLIVEIRA, M. M. ; FUSCO-ALMEIDA, A.-M. ;
VITE-GARIN, T. ; PITANGUI, N. S. ; ESTRADA-BARCENAS, D. A. ; GONZALEZ-GONZALEZ, A. E. ; MENDESGIANNINI, M. J. S. ; ZANCOPE-OLIVEIRA, R. M. ; TAYLOR, M.-L. Frequency and Genetic Diversity of the MAT1
Locus of Histoplasma capsulatum Isolated in Mexico and Brazil. Eukaryotic Cell, v. 12, p. 1033-1038, 2013.
10-OLIVEIRA, K. M. ; SILVA NETO, B. R. ; PARENTE, J.A. ; SILVA, R. A. ; QUINTINO, G. O. ; VOLTAN, A.R. ;
Mendes-Giannini, M.J.S. ; ALMEIDA SOARES, C.M. ; PEREIRA, M. . Intermolecular interactions of the malate
synthase of Paracoccidioides spp. BMC Microbiology (Online), v. 13, p. 107, 2013.
11-VICENTE, EDUARDO F. ; BASSO, LUIS GUILHERME M. ; CESPEDES, GRAZIELY F. ; LORENZÓN,
ESTEBAN N. ; CASTRO, MARIANA S. ; Mendes-Giannini, Maria José S. ; COSTA-FILHO, ANTONIO JOSÉ ; CILLI,
EDUARDO M. Dynamics and Conformational Studies of TOAC Spin Labeled Analogues of Ctx(Ile21)-Ha Peptide from
Hypsiboas albopunctatus. Plos One, v. 8, p. e60818, 2013.
12-TEODORO, V.L.I. ; GULLO, F.P. ; SARDI, J.C.O. ; FUSCO-ALMEIDA, A.M. ; MENDES-GIANNINI, M. J. S. .
Environmental isolation, biochemical identification, and antifungal drug susceptibility of Cryptococcus species. Revista
da Sociedade Brasileira de Medicina Tropical (Impresso), v. 46, p. 759-764, 2013.
13-GULLO, F. P. ; ROSSI, S. A. ; SARDI, J. DE C. O. ; TEODORO, V. L. I. ; MENDES-GIANNINI, M. J. S. ; FUSCOALMEIDA, A. M. Cryptococcosis: epidemiology, fungal resistance, and new alternatives for treatment. European Journal
of Clinical Microbiology & Infectious Diseases (Print), v. 32, p. 1377-1391, 2013.
14-VOLTAN, A.R. ; SARDI, J.C.O. ; SOARES, C.P. ; MACHADO, M.P. ; FUSCO-ALMEIDA, A.M. ; MendesGiannini, M.J.S. . Early Endosome Antigen 1 (EEA1) decreases in macrophages infected with <i>Paracoccidioides
brasiliensis</i>. Medical Mycology (Oxford. Online), p. 1-6, 2013.
15-BAILÃO, A.M. ; NOGUEIRA, S.V. ; BONFIM, S.M.R.C. ; CASTRO, K.P. ; SILVA, J.F. ; Mendes-Giannini, M.J.S. ;
PEREIRA, M. ; SOARES, C.M.A. Comparative transcriptome analysis of Paracoccidioides brasiliensis during in vitro
adhesion to type I collagen and fibronectin: identification of potential adhesins. Research in Microbiology (Paris), v. 163,
p. 182-191, 2012.
16-MARCOS, C.M. ; FÁTIMA DA SILVA, J. ; OLIVEIRA, H.C. ; SILVA, R.A.M. ; Mendes-Giannini, M.J.S. ; FUSCOALMEIDA, A.M. Surface-expressed enolase contributes to the adhesion of Paracoccidioides brasiliensis to host cells.
FEMS Yeast Research, v. 12, p. 557-570, 2012.
17-GULLO, F.P. ; SARDI, J.J.O. ; Santos, Vânia A. F. F. M. ; LEITE, F.S. ; PITANGUI, N.S. ; ROSSI, S.A. ; PAULA E
SILVA, A. C. ; Soares, Luciana A. ; FÁTIMA DA SILVA, J. ; OLIVEIRA, H.C. ; FURLAN, M. ; SILVA, D.H.S. ;
BOLZANI, V.S. ; Mendes-Giannini, M.J.S. ; FUSCO-ALMEIDA, A.M. Antifungal Activity of Maytenin and Pristimerin.
Evidence-Based Complementary and Alternative Medicine (Online), v. x, p. x, 2012.
18-FUNARI, C.S. ; GULLO, F.P. ; NAPOLITANO, A. ; CARNEIRO, R.L. ; Mendes-Giannini, M.J.S. ; FUSCOALMEIDA, A.M. ; PIACENTE, S. ; PIZZA, C. ; Silva, Dulce H. S. Chemical and antifungal investigations of six Lippia
species (Verbenaceae) from Brazil. Food Chemistry, v. 135, p. 2086-2094, 2012.
19-PITANGUI, N.S. ; SARDI, J.J.O. ; SILVA, J.F. ; BENADUCCI, T. ; SILVA, R.A.M. ; RODRIGUEZ-ARELLANES,
G ; TAYLOR, M.L. ; Mendes-Giannini, Maria José Soares ; FUSCO-ALMEIDA, A.M. Adhesion of Histoplasma
capsulatum to pneumocytes and biofilm formation on an abiotic surface . Biofouling (New York. Print), v. 28, p. 711-718,
2012.
20-CRUSCA JR, E. ; REZENDE, A.A. ; MARCHETTO, R. ; Mendes-Giannini, M.J.S. ; FONTES, W. ; CASTRO, M. S.
; CILLI, E. M. . Influence of N-terminus modifications on the biological activity, membrane interaction, and secondary
structure of the antimicrobial peptide hylin-a1. Biopolymers (New York. Print), v. 96, p. 41-48, 2011.
21-MIGLIATO, K.F. ; CORREA, M. A. ; TOGNOLLI, J. O. ; SACRAMENTO, L.V.S. ; MELLO, J. C. P. ; MendesGiannini, M.J.S. ; FUSCO-ALMEIDA, A.M. ; PIZZOLITTO, A.C. ; SALGADO, H. R. N. . Planejamento experimental
na otimização da extração dos frutos de Syzygium cumini (L.) skeels. Química Nova (Impresso), v. 34, p. 695-699, 2011.
22-PERES DA SILVA, R. ; MATSUMOTO, M.T. ; BRAZ, J.D. ; VOLTAN, A.R. ; SOARES, C.P. ; Mendes-Giannini,
M.J.S. . Differential gene expression analysis of Paracoccidioides brasiliensis during keratinocyte infection. Journal of
Medical Microbiology, v. 60, p. 269-280, 2011.
23-SARDI, J.J.O. ; FUSCO-ALMEIDA, A.M. ; Mendes-Giannini, M.J.S. . New antimicrobial therapies used against
fungi present in subgingival sites-A brief review. Archives of Oral Biology, v. 56, p. 951-959, 2011.
24-LEITE, F.S. ; SCORZONI, L. ; MESA-ARAGANO, A.C. ; CASAS, C. ; HERRERO, E. ; Mendes-Giannini, M.J.S. ;
RODRIGUES-TUDELLA, J.L. ; CUENCA-ESTRELLA, M. ; ZARAGOZA, O. . Amphotericin B mediates killing in
Cryptococcus neoformans through the induction of a strong oxidative burst. Microbes and Infection, v. 13, p. 457-467,
2011.
25-PIRES, R.H. ; MONTANARI, L.B. ; MARTINS, C.H.G. ; ZAIA, J.E. ; FUSCO-ALMEIDA, A.M. ; MATSUMOTO,
M.T. ; Mendes-Giannini, M.J.S. Anticandidal efficacy of cinnamon oil against planktonic and biofilm cultures of Candida
parapsilosis and Candida orthopsilosis. Mycopathologia (1975. Print), v. 172, p. 453-464, 2011.
26-PIRES, R.H. ; SANTOS, J.M. ; ZAIA, J.E. ; MARTINS, C.H.G. ; Mendes-Giannini, M.J.S. . Candida parapsilosis
complex water isolates from a haemodialysis unit: biofilm production and in vitro evaluation of the use of clinical
antifungals. Memórias do Instituto Oswaldo Cruz (Impresso), v. 106, p. 646-654, 2011.
27-PIRES, R.H. ; LUCARINI, R. ; Mendes-Giannini, M.J.S. . Effect of Usnic Acid on Candida orthopsilosis and C.
parapsilosis. Antimicrobial Agents and Chemotherapy (Print), v. 56, p. 595-597, 2011.
28-SILVA, M.G. ; SCHRANK, A. ; BAILAO, E.F.L.C. ; BAILÃO, A.M. ; BORGES, C.L. ; STAATS, C.C. ; PARENTE,
J.A. ; PEREIRA, M. ; IZAAC, S.M.S. ; Mendes-Giannini, M.J.S. ; ZANCOPÉ-OLIVEIRA, R.M. ; ROSA E SILVA, L.K.
; NOSANCHUK, J.D. ; VAINSTEIN, M.H. ; ALMEIDA SOARES, C.M. The homeostasis of iron, copper, and zinc in
paracoccidioides brasiliensis, cryptococcus neoformans var. Grubii, and cryptococcus gattii: a comparative analysis.
Frontiers in Microbiology (Online), v. 2, p. 1-19, 2011.
29-WERTHER, K. ; SOUZA, E. ; ALVES JUNIOR, J.R.F. ; ARDISSON, F.A. ; Mendes-Giannini, M.J.S. Cryptococcus
gattii and Cryptococcus albidus in Captive Domestic Pigeon (Columba livia). Brazilian Journal of Veterinary Pathology,
v. 4, p. 247-249, 2011.
30-MIGLIATO, K.F. ; MELLO, J. C. P. ; HIGA, O.Z. ; RODAS, A.C.D. ; CORREA, M. A. ; Mendes-Giannini, M.J.S. ;
FUSCO-ALMEIDA, A.M. ; PIZZOLITTO, A.C. ; SALGADO, H. R. N. Antimicrobial and cytotoxic activity of fruit
extract from Syzygium cumini (L.) skeels. Acta Farmacéutica Bonaerense, v. 29, p. 725-730, 2010.
31-REGASINI, L. O. ; PRIVATTO, M. ; SCORZONI, L. ; BENADUCCI, T. ; FUSCO-ALMEIDA, A.M. ; MendesGiannini, M.J.S. ; BARREIRO, E.J. ; SILVA, D.H.S. ; BOLZANI, V.S. . Antimicrobial activity of Pterogyne nitens Tul.,
Fabaceae, against opportunistic fungi. Revista Brasileira de Farmacognosia (Impresso), v. 20, p. 706-711, 2010.
32-CASTRO, M. S. ; FERREIRA, T. C. G. ; CILLI, E. M. ; CRUSCA JR, E. ; MENDES-GIANNINI, M.J.S. ; SEBBEN,
A. ; RICART, C. A. O. ; SOUZA, M.V. ; FONTES, W. Hylin a1, the first cytolytic peptide isolated from the arboreal
South American frog Hypsiboas albopunctatus ( spotted treefrog ). Peptides (New York), v. 30, p. 291-296, 2009.
33-DONÓFRIO, F.C. ; CALIL, A.C.A. ; MIRANDA, E.T. ; FUSCO-ALMEIDA, A.M. ; BENARD, G. ; SOARES, C.P. ;
VELOSO, S.N. ; SOARES, C.M.A. ; Mendes-Giannini, M.J.S. . Enolase from Paracoccidioides brasiliensis: isolation and
identification as a fibronectin-binding protein. Journal of Medical Microbiology, v. 58, p. 706-713, 2009.
34-CACERE, C.R. ; Mendes-Giannini, M.J.S. ; VALLE, A.C. ; DUARTE, A.J. ; BENARD, G. . Altered Ex Vivo
Expression of Caspase 8, Caspase 9, and Bcl-2 Is Associated with T-Cell Hyporeactivity in Patients with
Paracoccidioidomycosis. Clinical and Vaccine Immunology, v. 16, p. 953-955, 2009.
35-DEL VECCHIO, A. ; FÁTIMA DA SILVA, J. ; MONTEIRO DA SILVA, J.L. ; ANDREOTTI, P.F. ; SOARES, C.P. ;
BENARD, G. ; Mendes-Giannini, Maria José Soares . Induction of apoptosis in A549 pulmonary cells by two
Paracoccidioides brasiliensis samples . Memórias do Instituto Oswaldo Cruz (Impresso), v. 104, p. 749-754, 2009.
36-REGASINI, L. O. ; CONTIGUIBA, F. ; MORANDIM, A.A. ; KATO, M. J. ; SCORZONI, L. ; Mendes-Giannini,
M.J.S. ; BOLZANI, V.S. ; FURLAN, M. Antimicrobial activity of Piper arboreum and Piper tuberculatum (Piperaceae)
against opportunistic yeast. . African Journal of Biotechnology, v. 8, p. 2866-2870, 2009.
37-NETO, B.R. ; SILVA, J.D. ; Mendes-Giannini, M.J.S. ; LENZI, H.L. ; SOARES, C.P. ; PEREIRA, M. . The malate
synthase of Paracoccidioides brasiliensis is a linked surface protein that behaves as an anchorless adhesin. BMC
Microbiology (Online), v. 9, p. 272, 2009.
38-BARROS, L.C. ; FERREIRA JUNIOR, R.S. ; BARRAVIERA, S.R.C.S. ; STOLF, H.O. ; THOMAZINI-SANTOS,
I.A. ; Mendes-Giannini, M.J.S. ; MIRANDA, E.T. ; BARRAVIERA, B. A new fibrin sealant from Crotalus durissus
terrificus venom: Applications in Medicine. Journal of Toxicology and Environmental Health. Part B, v. 12, p. 553-571,
2009.
39-CASTRO, N.S. ; BARBOSA, M.S. ; MAIA, Z.A. ; BÁO, S.N. ; FELIPE, M.S.S. ; SANTANA, J.M. ; MENDESGIANNINI, M.J.S. ; PEREIRA, M. ; SOARES, C.M.A. Characterization of Paracoccidioides brasiliensis PbDfg5p, a cellwall protein implicated filamentous growth. . Yeast (Chichester), v. 25, p. 141-154, 2008.
40-PIRES-GONÇALVES, R.H. ; SARTORI, F.G. ; MONTANARI, L.B. ; ZAIA, J.E. ; MELHEM, M.S.C. ; MENDESGIANNINI, M.J.S. ; MARTINS, C.H.G. Occurrence of fungi in water used at a haemodialysis centre. Letters in Applied
Microbiology, v. 46, p. 542-547, 2008.
41-Mendes-Giannini, Maria José Soares ; MONTEIRO DA SILVA, J.L. ; FÁTIMA DA SILVA, J. ; DONÓFRIO, F.C. ;
MIRANDA, E.T. ; ANDREOTTI, P.F. ; SOARES, C.P. . Interactions of Paracoccidioides brasiliensis with host cells:
recent advances. Mycopathologia, v. 165, p. 237-248, 2008.
42-OLIVEIRA SILVA, R.B. ; FUSCO-ALMEIDA, A.M. ; MATSUMOTO, M.T. ; BAEZA, L.C. ; BENADUCCI, T. ;
MENDES-GIANNINI, M.J.S. ; MENDES-GIANNINI, M.J.S. Genetic diversity and antifungal susceptibility testing of
Trichosporon asahii isolated of intensive care units patients. Brazilian Journal of Microbiology, v. 392, p. 238-240, 2008.
43-CANDIDA DA SILVA, V. ; Mendes-Giannini, M.J.S. ; CARBONE, V. ; PIACENTE, S. ; PIZZA, C. ; BOLZANI,
V.S. ; LOPES, M.N. New antifungal terpenoid glycosides from Alibertia edulis (Rubiaceae). . Helvetica Chimica Acta, v.
91, p. 1355-1362, 2008.
44-VOLTAN, A.R. ; DONÓFRIO, F.C. ; MIRANDA, E.T. ; MORAES, R.A. ; Mendes-Giannini, M.J.S. Induction and
secretion of elastinolytic and proteolytic activity in cultures of Paracoccidioides brasiliensis. Revista de Ciências
Farmacêuticas Básica e Aplicada, v. 29, p. 97-106, 2008.
45-CACERE, C.R. ; Mendes-Giannini, M.J.S. ; FONTES, C.J. ; KONO, A ; DUARTE, A.J. ; BENARD, G . Altered
expression of the costimulatory molecules CD80, CD86, CD152, PD-1 and ICOS on T-cells from paracoccidioidomycosis
patients: Lack of correlation with T-cell hyporesponsiveness. Clinical Immunology (Orlando), v. 129, p. 341-349, 2008.
46-ALMEIDA SOARES, C.M. ; Mendes-Giannini, Maria José Soares ; FELIPE, M.S.S. ; CHATURVEDI, V. A
Centennial: Discovery of Paracoccidioides brasiliensis. Mycopathologia, v. 165, p. 179-181, 2008.
47-FIORENTINO, F.A.M. ; RICARTE, P.C. ; CORREA, M. A. ; Mendes-Giannini, M.J.S. ; ISAAC, V.L.B. ;
SALGADO, H. R. N. Análise microbiológica da embalagem para o acondicionamento de medicamentos e cosméticos.
Acta Farmaceutica Bonaerense, v. 27, p. 757-761, 2008.
48-MARQUI, S.R. ; LEMOS, R.B. ; SANTOS, L.A. ; CASTRO-GAMBOA, I. ; CAVALHEIRO, A.J. ; BOLZANI, V.S. ;
SILVA, D.H.S. ; SCORZONI, L. ; FUSCO-ALMEIDA, A.M. ; Mendes-Giannini, M.J.S. ; YOUNG, M. ; TORRES, L.B.
Saponinas antifúngicas de Swartzia langsdorffii. Química Nova (Impresso), v. 31, p. 828-831, 2008.
49-MONTEIRO DA SILVA, J.L. ; ANDREOTTI, P.F. ; BENARD, G. ; SOARES, C.P. ; MIRANDA, E.T. ; MENDESGIANNINI, M.J.S. Epithelial cells treated with genistein inhibit adhesion and endocytosis of Paracoccidioides
brasiliensis. Antonie van Leeuwenhoek, v. 92, p. 129-135, 2007.
50-PEREIRA, L.A., BÁO, S.N., BARBOSA, M.S., MONTEIRO DA SILVA, J.L., FELIPE, M.S.S., SANTANA, J.M.,
MENDES-GIANNINI, M.J.S., SOARES, C.M.A. Analysis of the Paracoccidioides brasiliensis triosephosphate isomerase
suggests the potential for adhesin function. FEMS Yeast Research.: 2,4620, v.7, p.1381 - 1388, 2007.
51- MENDES-GIANNINI, M.J.S., BAEZA, L.C., BAILÃO, A.M., BORGES, C L, PEREIRA, M., SOARES, C.M.A.
cDNA representational difference analysis used in the identification of genes expressed by Trichophyton rubrum during
contact with keratin. Microbes and Infection. v.9, p.1415 - 1421, 2007.
52-SCORZONI, L., BENADUCCI, T., FUSCO-ALMEIDA, A.M., SILVA, D.H.S., BOLZANI, V.S., MENDESGIANNINI, M.J.S. Comparative study of disk diffusion and microdilution methods for evaluation of antifungal activity of
natural compounds against medical yeast Candida spp and Cryptocuccus sp. Revista de Ciências Farmacêuticas Básica e
Aplicada. , v.28, p.25 - 34, 2007.
53-MONTEIRO DA SILVA, J.L., ANDREOTTI, P.F., BENARD, G., SOARES, C.P., MIRANDA, E.T., MENDESGIANNINI, M.J.S. Epithelial cells treated with genistein inhibit adhesion and endocytosis of Paracoccidioides
brasiliensis. Antonie van Leeuwenhoek.v.92, p.129 - 135, 2007.
54-GONÇALVES, R.H.P., MIRANDA, E.T., BAEZA, L.C., MATSUMOTO, M.T., ZAIA, J.E., MENDES-GIANNINI,
M.J.S. Genetic relatedness of commensal strains of Candida albicans carried in the oral cavity of patients’ dental
prosthesis users in Brazil. Mycopathologia. v.164, p.255 - 263, 2007.
55-MENDES-GIANNINI, M.J.S., MATSUMOTO, M.T., FUSCO-ALMEIDA, A.M., BAEZA, L.C., MELHEM, M.S.C.
Genotyping, serotyping and determination of mating-type of Cryptococcus neoformans clinical isolates from São Paulo
State. Revista do Instituto de Medicina Tropical de São Paulo.: 0,9590, v.49, p.41 - 47, 2007.
56-ANDREOTTI, P.F., MONTEIRO DA SILVA, J.L., TEIXEIRA, E. C., BERTOLINI, M.C., SOARES, C.P.,
BENARD, G., MENDES-GIANNINI, M.J.S.Identification of a gene encoding adaptin-like protein in the Paracoccidioides
brasiliensis genome by randon amplified polymorphic DNA analysis. Journal of Medical Microbiology.: 2,2970, v.56,
p.884 - 887, 2007.
57- FUSCO-ALMEIDA, A.M., MATSUMOTO, M.T., BAEZA, L.C., OLIVEIRA SILVA, R.B., KLEINER, A.A.P.,
MELHEM, M.S.C., MENDES-GIANNINI, M.J.S., & The Laboratory Group on Crytpcococosis
Molecular typing and antifungal susceptibility of clinical sequential isolates of Cryptococcus neoformans from São Paulo
State, Brazil. FEMS Immunology and Medical Microbiology. v.7, p.152 - 164, 2007.
58-SCORZONI, L., BENADUCCI, T., FUSCO-ALMEIDA, A.M., SILVA, D.H.S., BOLZANI, V.S., MENDESGIANNINI, M.J.S.The use of standart methodology for determination of antifungal activity of natural products against
medical yeasts Candida sp and Cryptococcus sp. Brazilian Journal of Microbiology. v.38, p.391 - 397, 2007.
59-COSTA, M., BORGES, C.L., BAILÃO, A.M., MEIRELLES, G., MENDONCA, Y.A., DANTAS, S.F.I.M., FARIA,
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66- BAEZA, L.C., MATSUMOTO, M.T., FUSCO-ALMEIDA, A.M., MENDES-GIANNINI, M.J.S.
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67-BENARD, G., KAVAKAMA, J., MENDES-GIANNINI, M.J.S., KONO, A., DUARTE, A.J., SHIKANAI-YASUDA,
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85-PIZZOLITTO, E.L., MENDES-GIANNINI, M.J.S. Candidíase vulvovaginal com episódios de repetição:
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96-SALINA, M.A., SHIKANAI-YASUDA, M.A., MENDES, R.P., BARRAVIERA, B., MENDES-GIANNINI, M.J.S.
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97-STOLF, H.O., BARRAVIERA, S.R.C.S., THOMAZINI-SANTOS, I.A., MIRANDA, E.T., MENDES-GIANNINI,
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98-THOMAZINI-SANTOS, I.A., MENDES-GIANNINI, M.J.S., MIRANDA, E.T., MACHADO, P.E.A., PRESTES,
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99- MENDES-GIANNINI, M.J.S., SARTORI-FILHO, PRESTES, N.C., THOMAZINI-SANTOS, I.A., BARRAVIERA,
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103-BENARD, G., MENDES-GIANNINI, M.J.S., JUVENALE, M., MIRANDA, E.T., DUARTE, A.J.
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106-MENDES-GIANNINI, M.J.S., TOSCANO, E., DEL NEGRO, G.M.B., ASSIS, C.M., GARCIA, N. Immunochemical
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107-MENDES-GIANNINI, M.J.S., RICCI, T.A., LEITE, C.Q.F., FALCAO, D.P. Isolamento e caracterização de Candida
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108- SHIKANAI-YASUDA, M.A., BENARD, G., DUARTE, A.J., LEITE, O.H.M., EIRA, M., MENDES-GIANNINI,
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109- IVAN, F.C., THOMAZINI-SANTOS, I.A., MENDES-GIANNINI, M.J.S., VITERBO, F., TOSCANO, E.,
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Books Chapters
1- BENARD, G., Mendes-Giannini, M.J.S. Textbook of Pediatric Infectious Diseases In: Paracoccidioidomycosis.7th ed.
Philadelphia : Elsevier Science, 2014, v.2, p. 2780-2795.
2-ARBEX, M., FUSCO-ALMEIDA, A.M., Mendes-Giannini, M.J.S. Criptococose In: Infecções Respiratórias.5 ed. :
Atheneu, 2013, v.5, p. 45-.
3- Mendes-Giannini, M.J.S., FUSCO-ALMEIDA, A.M. Infecções Fúngicas In: Diagnóstico Laboratorial das Principais
Doenças Infecciosas e Auto-Imunes.3 ed. : Guanabara Koogan, 2013, p. 87-.
4- Mendes-Giannini, M.J.S., MELHEM, M.S.C., FUSCO-ALMEIDA, A.M.
Infecções fúngicas In: Diagnóstico laboratorial das principais doenças infecciosas e auto-imunes. ed.Rio de Janeiro :
Guanabara Koogan, 2011, v.3
5-MELHEM, M.S.C., Mendes-Giannini, M.J.S., FUSCO-ALMEIDA, A.M.
Aplicação de Métodos de Biologia Molecular em Micologia Médica In: Compêndio de Micologia Médica ed. : Guanabara
Koogan, 2010, v.1, p. 50-74.
6-Mendes-Giannini, M.J.S., DEL NEGRO, G.M.B., GONCALVES, E.G.
Paracoccidioidomicose (Blastomicose sul-americana) In: Tratado de Infectologia.4 ed.São Paulo : Atheneu, 2010, p.
1533-1539.
7-BENARD, G., Mendes-Giannini, M.J.S. Textbook of Pediatric Infections Diseases In: Paracoccidioidomycosis.6
ed.Philadelphia : Elsevier Science, 2009, v.2, p. 2762-2776.
8- MENDES-GIANNINI, M.J.S., BENARD, G.
Paracoccidioidomicosis. In: Tratado SEIMC de Enfermedades Infecciosas y Microbiología Clínica.1 ed.Madrid : Médica
Panamericana, 2005, v.1, p. 675-680.
9- MENDES-GIANNINI, M.J.S.
Anticorpos monoclonais em micologia médica In: Tratado de Micologia Médica - LACAZ.9 ed.São Paulo : Sarvier, 2002,
p. 850-854.
10- MENDES-GIANNINI, M.J.S., MELHEM, M.S.C. Fungos In: Diagnóstico laboratorial das principais doenças
infecciosas e auto-imunes..2 ed.Rio de Janeiro : Guanabara Koogan, 2001, p. 333-403.
11-MENDES-GIANNINI, M.J.S., MENDES-GIANNINI, M.J.S., MELHEM, M.S.C. Fungos In: Diagnóstico laboratorial
das principais doenças infecciosas e auto-imunes..1 ed.Rio de Janeiro - RJ : Guanabara Koogan, 1996
12- MENDES-GIANNINI, M.J.S., VARANDA, E.A., MENDES-GIANNINI, M.J.S. Bioquimica de venenos de serpentes
In: Venenos animais - uma visão integrada ed. : Ed. Publ. Cient., 1994
13-MENDES-GIANNINI, M.J.S., DEL NEGRO, G.M.B., SIQUEIRA, A.M. Serodiagnosis of paracoccidioidomycosis
In: Paracoccidioidomycosis ed.Miami - USA : CRC Press, 1994, p. 343-363.
DEPOSITED PATENTS
- Mendes-Giannini, M.J.S. ; Mendes-Giannini, M.J.S. ; FUSCO-ALMEIDA, A.M. ; FUSCO-ALMEIDA, A.M. ;
CHORILLI, M. ; CHORILLI, M. ; BOLZANI, V.S. ; ALARCON, K.M. ; BOLZANI, V.S. ; SILVA, D.H.S. ;
REGASINI, L. O. ; DUTRA, L.A. ; SARDI, J.C.O. . Incorporação de 2-chalcona em sisetemas lipídicos nanoestruturados
composição e uso no tratamento da Paracoccidioidomicose. 2013, Brazil. Número do registro: 13CI035
- Iuan, FC; Thomazini I A; Moraes, RA; Viterbo de Oliveira Neto, F; Mendes Giannini, MJ; Barraviera, B., Toscano, E.
Cola de fibrina derivada de veneno de cobra e processo para sua preparação. Number of the patente with the INPIPI9103724-7, Classified -C09J 189/00 -Dep. no INPI:29/08/1991
SUPERVISION OF MASTER DISSERTATIONS AND PhD THESIS - COMPLETED
- Master's Dissertation
1. Jaqueline Derissi Braz : Gene expression of adhesins and virulence of the yeast and mycelial phase Paracoccidioides
complex and its interaction with epithelial cells and phagocytes. Sponsors: CNPq, date of defense: 2013
2. - Ana Carolina de Paula e Silva: Evaluation of alkyl gallates anti- Paracoccidioides complex by phenotypic and
proteomic methods: Sponsor- CAPES-2012.
3. Roberta Peres da Silva : Analysis of cDNA differentially expressed during infection with Paracoccidioides brasiliensis
keratinocytes and pneumocytes. Sponsors: FAPESP, 2010.
4. Fernanda Sangalli Leite: Phenotypic and protein expression of Cryptococcus neoformans after treatment with
compounds obtained from plant Pterogyne nitens. Sponsor-CAPES, 2010.
5.- Haroldo César de Oliveira. Influence of copper in the genes expression pattern involved in the interaction of
Paracoccidioides brasiliensis with the extracellular matrix. Sponsor- FAPESP-2010.
6.-Tatiane Benaducci. Susceptibility of synthetic and natural antifungal anti-Cryptococcus neoformans determined by
flow cytometry. Sponsor-CAPES, 2009.
7-Julhiany de Fátima da Silva. Study of different isolates of P. brasiliensis based on the pattern of expression of adhesion
ligands and extracellular matrix. Sponsor- CAPES, 2008.
8- Liliana Scorzoni. Study of antifungal activity and protein expression profile in Candida yeasts after treatment with
extracts Kielmeyera rubriflora. Sponsor- CAPES, 2008.
9-Aline Raquel Voltan. Evaluation of adhesion molecules and the endocytic pathway in the interaction Paracoccidioides
brasiliensis cells of the host. 2008.
10- Fabiana Cristina Donofrio. Isolation and characterization of Paracoccidioides brasiliensis adhesin binding to
fibronectin. Sponsor- FAPESP, 2007.
11- Regina Helena Pires Gonçalves. Hemodialysis machines: ability to form biofilms in vitro isolates of Candida
parapsilosis. Molecular aspects, and cellular resistance to antifungal. 2007.
12-José Sebastião Correa Neto. Spoilage molds in parmesan cheese. 2005. Co-supervisor.
13- Simone Manzani Vivaldini. Molecular typing of Cryptococcus neoformans sequential patients in the region of São
José do Rio Preto - SP and correlation with susceptibility to antifungal drugs. 2003.
14-José Nelson Martins Diniz. Monitoring of yeasts and filamentous fungi from abiotic and biotic sources in a Hospital
Unit. CAPES, 2003.
15-Gérson Aparecido Andrade. Cryptococcus neoformans: phenotypic and genotypic aspects of environmental isolates of
Araraquara region. CAPES. 2003.
16-Lilian Cristiane Baeza. Analysis of differentially expressed cDNA in the presence of keratin and molecular typing of
Trichophyton rubrum. CNPq, 2003.
17-Catia Rezende. Phenotypic and molecular aspects of Cryptococcus neoformans from the region of Araraquara and
Ribeirao Preto related to susceptibility profiles. FAPESP-2002.
18-Patrícia Ferrari Andreotti. Isolation and characterization of the adhesin involved in the interaction with epithelial cells
Paracoccidioides brasiliensis. CAPES, 2002.
19-Leonilda Chiari Galle. Association of the presence of Candida species and changes in the squamous cells of the cervix.
2002.
20- Elaine Toscano Miranda. Identification of Candida species from different hospitals by classical and PCR-enzyme
immunoassay techniques. Standard genotypic and susceptibility to antifungal drugs. 2001.
21-Ana Marisa Fusco Almeida. Karyotype analysis of different samples of Cryptococcus neoformans and correlation with
susceptibility to antifungal drugs. 2000.
22-Juliana Leal Monteiro da Silva. Adhesion, binding to fibronectin and invasion of Paracoccidioides brasiiensis in
cultured Vero cells. 2000.
23-Luciana Raquel Vincenzi. Molecular basis of the adhesion process of Paracoccidioides brasiliensis to extracellular
matrix proteins. CAPES. 2000.
26-Mauro Cintra Giudice. Mycoses in patients with the HIV virus. Therapeutic and clinical laboratory aspects. 1997.
27-Samira Abdallah Hanna. Study of the virulence mechanisms and Paracoccidioides brasiliensis factors in cell
cultures.1996.
28-Margarete Aparecida Salina. Detection and characterization of antigens and verification of proteolytic activity in
extracts of P. brasiliensis and biological materials. FAPESP-1996.
29.Elisabeth Loshchagin Pizzolitto. Epidemiology and pathogenesis of recurrent vulvovaginal candidiasis. Identification,
serotyping, biotyping, killer factor of Candida albicans. 1994.
Doctoral Thesis
1.Tatiane Benaducci. Suscetibility of biofilms Cryptococcus neoformans the synthetic and natural antifungal determined
by flow cytometry. CAPES, 2013.
2.Aline Raquel Voltan. Determination of gene / proteins endosomal of Paracoccidioides brasiliensis in infected and
uninfected macrophages. 2013.
3.Liliana Scorzoni. Antifungal unconventional models to study host-fungus interaction. CAPES, 2012.
4-Julhiany de Fátima da Silva. Activation of Rho GTPases and other signaling molecules during interaction of
Paracoccidioides brasiliensis with epithelial cells. CAPES, 2011.
5.Regina Helena Pires Gonçalves. Biofilm formation and antifungal and biocides resistance to Candida parapsilosis and
C. arthopsilosis isolated from water used for hemodialysis.. 2010.
6-José Nelson Martins Diniz. Cryptococcus neoformans from environmental sources and bioprospecting of plant extracts
with activity sanitizing. 2009.
7.Patrícia Ferrari Andreotti. Interaction of P. brasiliensis with epithelial cells. Isolation, characterization and adhesins
signaling events . CAPES, 2006.
8.Marcelo Teruyuki Matsumoto. Molecular typing of susceptibility profiles and characterization of differentially
expressed transcripts during infection of Cryptococcus neoformans.CNPq, 2006.
9.Elaine Toscano Miranda. Comparative study of P. brasiliensis isolates in relation to cell adhesion. Cell signaling
mediated by gp43. 2006.
10.Lilian Cristiane Baeza. Analysis of differentially expressed genes of Trichophyton rubrum in the presence of molecular
typing and keratin. CNPq, 2006.
11.Susana D'avila. Clinical and laboratory evaluation of denture stomatitis. 2006. Co-supervisor
12.Ana Marisa Fusco Almeida. Molecular characterization of the ERG11 gene polymorphisms and associated
mechanisms of resistance to antifungal drugs in clinical isolates of C. neoformans. 2005.
13.Rosana Bellan de Oliveira e Silva. Investigation of yeasts in hospitals by different molecular techniques. 2005.
14.Juliana Leal Monteiro da Silva. Adherence and invasion of Paracoccidioides brasiliensis in cultured cells: involvement
of cytoskeletal signaling event and occurrence of apoptosis. 2004.
15.Margarete Aparecida Salina. Evolutionary analysis of serum antibodies and specific antigens in patients with
paracoccidioidomycosis. 2002.
16. Vera Lucia Dias da Silva Fontana. Etiology of subclinical mastitis in the region of Jatahy - GO. Standard genotypic
and susceptibility to antimicrobial drugs with emphasis on Staphylococcus. 2002.
17.Samira Abdallah Hanna. Interaction of Paracoccidioides brasiliensis with the extracellular matrix and cytoskeletal
involvement in adhesion and invasion of epithelial cells. 2001.
SUPERVISION OF POST-DOC
1-Marcelo Teruyuki Matsumoto. Caracterização fenotípica e de genes diferencialmente expressos de Cryptococcus
neoformans após interação com pneumócitos e com extratos com atividade antifúngica. 2009. Universidade Estadual
Paulista Júlio de Mesquita Filho, Projeto GENOPROT - FINEP. Maria José Soares Mendes Giannini.
2-Marcelo Teruyuki Matsumoto. 2008.
3-Ana Marisa Fusco Almeida. 2008.
4-Patrícia Ferrari Andreotti. Activation of RhoGTPases and other signaling molecules of this pathway by recombinant 143-3 protein of P. brasiliensis during their interaction with epithelial cells. FAPESP-06/52906-0; 2007.
5-Carla Cristina Romano.. Participation of intracellular signaling pathways (Stats) and its regulation by cytokines in the
immune response of patients with paracoccidioidomycosis and sensitized healthy individuals. FAPESP- 02/14026-7-2005
SOME IMPORTANT APPROVED GRANT
1. Project: Characterization and functional analysis of the 14-3-3 protein involved in the accession process of
Paracoccidioides sp gene complex and identification of potential targets in the therapy of paracoccidioidomycosis.
Coordinator: Prof. Maria Jose Mendes Giannini; FAPESP, Process 11/18038-9
2. Project: Candida parapsilosis and C. orthopsilosis isolated from hemodialysis water: application of proteomic and
photocatalysis methodologies.
Coordinator: Prof. Maria Jose Mendes Giannini; FAPESP, Process 12/01270-9
3. Project: EMU: multiuser equipment for multiparametric analysis in cellular models with potential use in the
identification of therapeutic and toxicants targets / In Cell Analyzer 2000
Coordinator: Prof. Maria Jose Mendes Giannini; FAPESP 09/54222-9
4. Project: Analysis of genes differentially expressed during contact of P. brasiliensis extracellular matrix components,
pneumocytes and keratinocytes
Coordinator: Prof. Maria Jose Mendes Giannini: FAPESP- 09/52046-9
5. Project: Phenotypic and differentially expressed genes of Cryptococcus neoformans after interaction with pneumocytes
and extracts with antifungal activity characterization. FAPESP- 07/53253-2
6. Project: Analysis of cDNA differentially expressed during infection and molecular typing of Trichophyton rubrum
7. Project: Signaling events in the interaction of P. brasiliensis with epithelial cells and mononuclear cells involved in
immune response. FAPESP Thematic Project, No. 02/07306-3
8. Project: Molecular aspects of the adhesion process and invasion of P. brasiliensis in cell cultures. FAPESP: 97/097023.
8.Project: Alternative models in vivo to study unconventional antimicrobials from different sources. CNPq-RENAMA.
9. Cooperação Internacional no Programa Nacional de Cooperación Internacional Europeu-Oscar Zaragoza.2008
10. Search for potential antitumoral, antioxidant, anti-inflammatory, amtifungal, antidiabetic, acetylcholinesterase and
myeloperoxidase inhibitory natural compounds from Cerrado and Atlantic Forest. Participation-Bioprospecta-FAPESPProcesso 2004/07932-7. 2004.
11. Program of Infrastructure FINEP for Excellence in Chemical Analysis - Biolog. Center for proteomics. 2010.
RESEARCH FELLOWSHIP IN PROGRESS
Research fellowship from CNPq, level 1A, Process n º 309798/2013-2: 2014-2017.
SUPERVISION OF MASTER AND PHD - IN PROGRESS
1.Junya de Lacorte Singulani. Evaluation of antifungal activity of gallates and amphotericin B associated with graphite
nanoparticles in vivo models with Caenorhabditis elegans, Galleria mellonella and mice. CAPES- início: 2013.
2.Ana Carolina Alves de Paula e Silva. The role of compounds derived from gallic acid anti-Paracoccidioides activity
using in vitro and in vivo models. CAPES- Início: 2012.
3.Caroline Barcelos C. Orlandi. Development of anti-dermatophytic prototypes derived from protocatechuic acid. CNPqInício: 2012.
4.Haroldo César de Oliveira. Identification of adhesin in different phylogenetic species of Paracoccidioides brasiliensis by
Phage Display. CAPES-Início: 2010.
5.Fernanda Sangalli Leite. Genomics and proteomics approach in prospecting antifungal bioactive against Cryptococcus
species.CAPES. Início: 2010.
SUPERVISION OF POST- DOCTORATE - IN PROGRESS
1-Regina Helena Pires. C.parapsilosis e C. orthopsilosis isolated from haemodyalisis water. Aplication of proteomic and
photocatalisis method. 2012. UNESP; FAPESP scholarship- 11/12734-3
2-Julhiany de Fátima da Silva. The role of non-coding RNA in the virulence of human pulmonary fungal pathogens and
production of monoclonal antibodies for diagnosis and treatment. 2012. UNESP- PROPe/UNESP.
3-Liliana Scorzoni-Antifungal deployment of unconventional animal models for the study of fungus-host integration.
2012. UNESP- PROPe/UNESP.
4-Liliana Scorzoni- Alternative animal models: virulence of different phylogenetic species of Paracoccidioides and effect
of 43kDa and 30kDa proteins and their antibodies. FAPESP- 13/10917-9
5-Janaina de Cássia Orlandi Sardi. Transcriptional analyzes of the process of biofilm formation by Paracoccidioides
brasiliensis and the role of adhesins and their antibodies. 2011. UNESP- CNPq-scholarship.
6-Julhiany de Fátima da Silva. Characterization and functional analysis of the 14-3-3 protein gene involved in the
accession process of Paracoccidioides sp complex. 2012. PROPe/UNESP.
7-Janaína de Cassia Orlandi Sardi. 2011. Identifying non-coding RNA in the virulence of human pulmonary fungal
pathogens. CNPq- 500478/2011-2.
OTHER INFORMATION
Member of the CAPES Evaluation Committee of the Pharmacy Graduate Program of BrazilVice-Dean of the Faculty of Pharmaceutical Sciences, UNESP, for 1994-97,
Coordinator of the Graduate Program in Bioscience and Biotechnology Applied to Pharmacy (Clinical Analysis), Faculty
of Pharmaceutical Sciences in three terms (2000-02; 2002-04, 2007-09),
Vice-president of the Brazilian Society of Mycology (2000-02) and vice-president of the Brazilian Society of
Microbiology (2006-2009).
FAPESP's Board of Trustees- 2009-2015.
Research Vice-president of Univ Estadual Paulista-UNESP-2009-2012-2013-2016.
ACADEMIC DISTINCTIONS AND PRIZES, MOST RELEVANT:
2014- Winner of "Carlyn Halde Latin American Student Travel Award" during 114th ASM General Meeting. Caroline
Barcelos- doctorate student. In vitro characterization of Trichophyton rubrum and T. mentagrophytes biofilms.
2011-Work selected as during the 1st EXCELLENT BBEST Brazilian BioEnergy Science and Technology Conference,
with the work entitled “Selection of wild strains tolerant to stress factors”, Brazilian BioEnergy Science and Technology
Conference.
2010-Prize for the best scientific work in SINPOSPq IV, with the work entitled “Ocurrence of Cryptococcus sp in
excrement of pigeon in the city of Araraquara, São Paulo State, Brazil”, SINPOSPq
2007-Professor honored for contributions to the Graduate Program in Clinical Analysis of FCF - UNESP, Faculty of
Pharmaceutical Sciences of Araraquara - UNESP.
2004-Photo cover of the magazine with the article: Invasion of epithelial mammalian cells by Paracoccidioides
brasiliensis leads to cytoskeletal rearrangement and apoptosis of the host cell. Mendes-Giannini, M.J.S. et al. Microbes
Infection.
2002-3rd Place - 2002 Award Panel Session Biochemistry, Molecular and Cellular Biology, Genetics; with work:
“Internalization of P. brasiliensis and cytoskeletal organization by epithelial cells”, authored by Mendes-Giannini, MJS et
al, VII International Meeting on Paracoccidioidomycosis.
2001-II Prize for Biomerieux / SBM as the best work in the area of Hospital Infection, work with Molecular identification
and susceptibility typing prolifes from nosocomial yeast strains, authored by MIRANDA, ET, MENDES-GIANNINI, et
al., Brazilian Society of Microbiology / Biomerieux.