clarinetes Peter Eaton

CURRICULUM VITAE
Name: Eulália Fernanda Alves de Carvalho Pereira
Date and place of Birth: Porto, Portugal, 7th September, 1964
Nationality: Portuguese
Home Address:
Rua Fernão de Magalhães, 70, rc-esq, 4400-145 V. N. Gaia,
Portugal
Office Address: Departamento de Química e Bioquímica, Faculdade de
Ciências do Porto, Rua do Campo Alegre, 687, 4169-007
Porto, Portugal
e-mail: [email protected]
EDUCATION
Ph.D., Chemistry, Faculdade de Ciências da Universidade do Porto, October
1996.
B.Sc., Chemistry, Faculdade de Ciências da Universidade do Porto, September,
1986 (Classification: 16/20)
ACADEMIC/TEACHING EXPERIENCE
Assistant Professor, Departamento de Química, Faculdade de Ciências do Porto,
1996-to date
Teaching Assistant, Departamento de Química, Faculdade de Ciências do Porto,
1986-1996
Demonstrator, Departamento de Química, Faculdade de Ciências do Porto, 1986
COURSES TAUGHT:
Undergraduate:
Graduate:
General Chemistry
Biological Inorganic Chemistry
Inorganic Chemistry
Applied Inorganic Chemistry
Bioinorganic Chemistry
Nanochemistry
Bioinorganic Chemistry Laboratory
Physical Inorganic Chemistry
Materials in Chemistry and Biochemistry
RESEARCH ACTIVITY:
1) Nanochemistry
a) Optimization of photochemical reduction of metal complexes in several
media (micelles, vesicles, liquid-crystals, etc).
b) Development of new methodologies for the synthesis of non-spherical
nanoparticles
c) Development of new methodologies for the synthesis of core-shell
nanoparticles (silica, metals, metal oxides)
d)
Characterization
of
the
nanostructures
by
Transmission
Electron
Microscopy (TEM)
e) Study of the interaction of nanoparticles with biomolecules
f) Nanotoxicology
2) Metallosurfactants
a) Synthesis of ligands and metal complexes with amphiphilic properties.
b) Chemical characterization: E.A, FAB-MS, 1H and
13
C NMR, FTIR, UV-vis,
electrochemistry.
c) Morphological characterization: Electron microscopy (TEM, SEM and cryoSEM), Dynamic light-scattering
d) Langmuir-Blodgett films
e) Applications in catalysis
RECENT PARTICIPATIONS IN RESEARCH PROJECTS:
Principal investigator:
“Metal and magnetic nanoparticles functionalized with biological molecules as
bionanoprobes” PTDC/QUI/64484/2006 (finished)
“Nanostructures of noble metals in organized media: technological applications”
POCTI/QUI/45145/2002 (finished)
“Photocatalytic Growth of Metal Nanostructures”
Foundation for the Development)
FLAD
(Luso
American
Researcher:
“Desenvolvimento de um novo método imunológico para o rastreio da
leishmaniose
canina
utilizando
nanoparticulas
de
ouro
coloidal”
PTDC/CVT/110732/2009
“Multifunctional
Nanoparticles
for
Clinical
Diagnosis”
PTDC/CTM-
NAN/109877/2009
“Sensitive and selective detection of DNA/RNA based on functionalised gold
nanoparticles - application to pathogen detection; mutation detection and RNA
quantification” PTDC/BIO/66514/2006 (finished)
“Nanodiagnostics: gold-nanoprobes for molecular recognition - application to
DNA adducts detection; pathogen detection; gene expression and RNA
quantification” PTDC/SAU-BEB/66511/2006 (finished).
“Design of new metallosurfactants with catalytic relevance: physico-chemical,
morphological and reactivity study” POCTI/QUI/38605/2001(finished).
“Synthesis, structure, properties, speciation in solution and biological studies of
vanadium compounds for the treatment of diabetes.”POCTI/QUI/35368/1999
(finished).
“Study
of
biogenic
polyamines
and
their
metal
complexes.”
POCTI/QUI/33199/1999 (finished).
SUPERVISION OF GRADUATE STUDENTS
Ph.D students:
Paula Maria Leandro Garcia, 2002. Dissertation: “Amphiphilic complexes of
iron(II) – morphological and physico-chemical characterization”. Departamento
de Química, Faculdade de Ciências da Universidade do Porto.
Maria
Adelaide
de
Carvalho
Miranda,
7/03/2011.
Dissertation:
“Metal
nanostructures – synthesis and applications”. Departamento de Química,
Faculdade de Ciências da Universidade do Porto.
Pedro Correia Quaresma, 2007-2012: “NPs with a magnetic core and Au shell for
detection and separation of biomolecules”. Departamento de Química,
Faculdade de Ciências da Universidade do Porto.
Cristina Sofia Neves, 2010-, Dissertation: " Synthesis of novel metal-quantum dot
nanoparticles and their use in genetic biosensors", Programa Doutoral em
Química Sustentável, REQUIMTE, UP/FCT-UNL
Leonor
Ricardo
Soares,
2011-,
Dissertation:
"Nanopartículas
de
ouro
anisométricas como sondas para identificação de polimorfismos de DNA
associados
a
doenças
metabólicas"
Programa
Doutoral
em
Química
Sustentável, REQUIMTE, UP/FCT-UNL
Master Students:
Ana Cristina da Silva Maia, 2000. Dissertation: “Synthesis of iron(II) complexes
with ligands derived from 2,2’-bipyridine and cyanide – Polarity probes for pure
solvents” Departamento de Química, Faculdade de Ciências da Universidade do
Porto.
Inês Maria Osório, 2008. Dissertation: “Photocatalytic synthesis of asymmetric
gold and silver nanoparticles”, Departamento de Química, Faculdade de
Ciências da Universidade do Porto.
Leonor Soares, 2009. Dissertation: “Synthesis and functionalization of metal
nanoparticles with peptides”, Departamento de Química, Faculdade de Ciências
da Universidade do Porto.
Eliana Malheiro, 2010. Dissertation: “Kinetic effects in the morphological control
of gold nanoparticles”, Departamento de Química, Faculdade de Ciências da
Universidade do Porto.
Armando Silva, 2010. Dissertation: “Development of methodologies for the
synthesis of metal nanoparticles by green chemistry methods”, Departamento de
Química, Faculdade de Ciências da Universidade do Porto.
Vânia M. P. Vieira, 2011. Dissertation: "Preparação e Funcionalização de
Nanopartículas Para Bioensaios." Faculdade de Ciências da Universidade do
Porto.
Catarina A. D. Loureiro, 2011. Dissertation: "Preparação de Nanopartículas
Metálicas Funcionalizadas com Péptidos para Aplicações em Biossensores",
Faculdade de Ciências da Universidade do Porto.
SUPERVISION OF POST-DOCTORATE PROJECTS
Dr. Pedro Quaresma, 2013-. Project: Bionanoconjugates of magnetic/gold
nanoparticles and laccase for application in the detection and degradation of
environmental pollutants. REQUIMTE-Departamento de Química, Faculdade de
Ciências da Universidade do Porto.
Dr. Inês Gomes, 2011-. Project: "Malaria Bionanodiagnosis: Gold nanoparticlebased rapid detection test for malaria parasites in clinical samples". Instituto de
Medicina Molecular/REQUIMTE (Porto)
Dr. Peter Jonathan Eaton, 2004-2006. Project: “AFM characterization of
nanostrutures and nanostructured materials”. REQUIMTE-Departamento de
Química, Faculdade de Ciências da Universidade do Porto.
Dr. Sunita Arun Salunke, 2004-2007. Project: “Metallosurfactants – synthesis,
characterization and aggregation properties”. REQUIMTE-Departamento de
Química, Faculdade de Ciências da Universidade do Porto.
Dr. Elzbieta Skiba, 2005-2006. Project: “Metal nanostructures for catalytic and
biological applications”. REQUIMTE-Departamento de Química, Faculdade de
Ciências da Universidade do Porto.
PUBLICATIONS
1
Copper(II)
complexes
with
1-(2-carbamylethyl)-2-alkylimidazoles
and
oxyanions.
M. C. R. M. P. Basto, M. J. P. Ferreira, E.F. A. C. Pereira e A. Machado
Polyhedron., 1990, 9, 2035.
2
Chemical generation and decomposition of Schiff bases nickel(III)
complexes with a N2O2 chromophore.
Baltazar de Castro, Cristina Freire, Eulália Pereira
J. Inorg. Biochem., 1991, 43, 653.
3
Decomposition of chemically and electrochemically generated Ni(III)
complexes with N2O2 Schiff-base ligands..
Baltazar de Castro, Cristina Freire e Eulália Pereira
J. Chem. Soc., Dalton Trans., 1994, 571.
4
Nickel complex with an asymmetric N2OS Schiff base ligand.
Baltazar de Castro, Eulália Pereira e Lígia Gomes
Acta Cryst., 1997, C53, 1572.
5
Synthesis, spectroscopic and electrochemical study of nickel(II) complexes
with tetradentate asymmetric Schiff bases derived from salycilaldehyde and
methyl 2-aminocyclopentene-dithiocarboxylate.
Eulália Pereira, Lígia Gomes e Baltazar de Castro
Inorg. Chim. Acta 1998, 271, 83.
6
Synthesis, spectroscopic and electrochemical study of nickel(II) and
nickel(I) complexes with Schiff base ligands with a NN’OS coordination
sphere.
Eulália Pereira, Lígia Gomes e Baltazar de Castro
J. Chem. Soc. Dalton Trans. 1998, 629.
7
Nickel complex with a tetradentate N2S2 Schiff-base ligand.
Lígia Gomes, Eulália Pereira e Baltazar de Castro
Acta Cryst., 1999, C55, 1061-1062
8
Study of copper(II) polyazamacrocylclic complexes by electronic absorption
spectrophotometry and EPR spectroscopy.
Carlos F. G. C. Geraldes, M. Paula M. Marques, Baltazar de Castro, Eulália
Pereira
Eur. J. Inorg. Chem., 2000, 559-565
9
Bis-(4-methyl-4’-pentyl-2,2’-bipyridyl)(dicyano)-iron(II):
a
versatile
solvatochromic solvation probe.
Paula Gameiro, Ana Maia, Eulália Pereira, Baltazar de Castro e John
Burgess
Trans. Met. Chem., 2000, 25, 283-286.
10
Nickel (II) complexes with N2OS and N2S2 co-ordination spheres:
Reduction and spectroscopic study of the correspondent Ni (I) complexes.
Lígia Gomes, Eulália Pereira, Baltazar de Castro
J. Chem. Soc., Dalton Trans., 2000, 1373-1379.
11
Structural study of the interaction of vanadate with the ligand 1,2-dimethyl3-hydroxy-4-pyridinone (HDMPP) in aqueous solution.
M.M.C.A.Castro, C.F.G.C.Geraldes, P. Gameiro, E. Pereira, B. Castro, M.
Rangel.
J. Inorg. Biochem., 2000, 80, 177-179
12
Derivatives of bis-2,2'-bipyridyl)dicyano)iron(II) with long alkyl chains Versatile solvatochromic probes that form metalloaggregates in water-rich
media .
Paula Gameiro, Eulália Pereira, Paula Garcia, Sónia Breia, John Burgess e
Baltazar de Castro
Eur. J. Inorg. Chem., 2001, 2755-2761.
13
A novel self-indicative vesicle based on a iron(II) complex.
Paula Garcia, João Marques, Eulália Pereira, Paula Gameiro, Roberto
Salema e Baltazar de Castro
Chem.Comm., 2001, 1298-1299.
14
Characterization of the photolysis products of sec-butylcobaloximes with
imidazole and benzimidazole bases.
Maria Rangel, Eulália Pereira, Celeste Oliveira, Baltazar de Castro
J. Organomet. Chem., 2001, 632, 85-93.
15
Cytotoxic effects of metal complexes of biogenic polyamines. I. Platinum(II)
spermidine compounds: prediction of their antitumour activity.
M. P. ;. Marques, T. Girão, Maria C. Pedroso de Lima, A. Gameiro, E.
Pereira, P. Garcia
Biochim. Biophys. Acta, 2002, 1589, 63-70.
16
Controlled Synthesis of 2-D and 3-D Dendritic Platinum Nanostructures.
Y. Song, Y. Yang, C. J. Medforth, E. Pereira, A. K. Singh, H. Xu, Y. Jiang,
C. J. Brinker, F. van Swol, J. A. Shelnutt
J. Am. Chem. Soc. 2004, 126, 635-645.
17
Two azurins with unusual redox and spectroscopic properties isolated from
the Pseudomonas chlororaphis strains DSM50083T and DSM50135.
D. Pinho, S. Besson, C. D. Brondino, E. Pereira, B. De Castro e I. Moura
J. Inorg. Biochem. 2004, 98, 276-286.
18
Cytotoxic Activity of Metal Complexes of Biogenic Polyamines: Polynuclear
Platinum(II) Chelates.
Luísa J. Teixeira, Marta Seabra, Elisa Reis, M. Teresa Girão da Cruz, M.
Conceição Pedroso de Lima, Eulália Pereira, M. Adelaide Miranda e M.
Paula M. Marques
J. Med. Chem. 2004, 47, 2917-2925.
19
“Colorimetric detection of eukaryotic gene expression with DNA-derivatized
gold nanoparticle”, P. Baptista, G. Doria, D. Henriques, E. Pereira, R.
Franco,
J.
Biotechnol.,
2005,
Vol
119
(2),
111-117,
DOI:10.1016/j.jbiotec.2005.02.019
20
“Mossbauer effect studies on the formation of iron oxide phases
synthesized via microwave-hydrothermal route”, Bakare, P. P., Date, S. K.,
Khollam, Y. B., Deshpande, S. B., Potdar, H. S., Salunke-Gawali, S., Varret,
F., and Pereira, E., Hyperfine Interact. 2006, 168, 1127-1132.
21
“Imaging gold nanoparticles for DNA sequence recognition in biomedical
applications”, Eaton, P., Doria, G., Pereira, E., Baptista, P. V., and Franco,
R., IEEE T. Nanobiosci. 2007, 6, 282-288.
22
“AFM and electron microscopy study of the unusual aggregation behavior of
metallosurfactants based on iron(II) complexes with bipyridine ligands”,
Garcia, P., Eaton, P., Geurts, H. P. M., Sousa, M., Gameiro, P., Feiters, M.
C., Nolte, R. J. M., Pereira, E., and de Castro, B, Langmuir 2007, 23, 79517957.
23
“beta-Blockers and benzodiazepines location in SDS and bile salt micellar
systems - An ESR study”, Reis, S., Moutinho, C. G., Pereira, E., de Castro,
B., Gameiro, P., and Lima, J. L. F. C., J. Pharmaceut. Biomed. 2007, 45,
62-69.
24
“Synthesis, spectroscopic, electrochemical and structural characterization of
Cu(II) complexes with asymmetric NN'OS coordination spheres”, Pereira,
E., Gomes, L. R., Low, J. N., and de Castro, B., Polyhedron 2008, 27, 335343.
25
“Gold nanoparticles for the development of clinical diagnosis methods”,
Baptista, P.; Pereira, E.; Eaton, P.; Doria, G.; Miranda, A.; Gomes, I.;
Quaresma, P.; Franco, R. Anal. Bioanal. Chem. 2008, 391, 943-950.
26
“Probing Surface Properties of Cytochrome c at Au Bionanoconjugates”,
Gomes, I.; Santos, N. C.; Oliveira, L. M. A.; Quintas, A.; Eaton, P.; Pereira,
E.; Franco, R. J. Phys. Chem. C 2008, 112, 16340-16347.
27
“Atomic force microscopy study of the antibacterial effects of chitosans on
Escherichia coli and Staphylococcus aureus”, Eaton, P.; Fernandes, J.C.;
Pereira E., Pintado, M.E.; Malcata, F. X. Ultramicroscopy 2008, 108, 11281134
28
“Green photocatalytic synthesis of stable Au and Ag nanoparticles”,
Quaresma, P.; Soares, L.; Contar, L.; Carvalho, P.A.; Franco, R.; Pereira,
E. Green Chem. 2009, 11, 1889-1893
29
“Novel
3-hydroxy-4-pyridinonato
oxidovanadium(IV)
complexes
to
investigate structure/activity relationships”, Rangel, M.; Amorim M.J.;
Nunes, A., Leite, A., Pereira, E.; de Castro, B.; Sousa, C.; Yoshikawa, Y.;
Sakurai, H. J. Inorg. Biochem. 2009, 103, 496-502
30
“Superparamagnetic γ-Fe2O3@SiO2 nanoparticles: a novel support for the
immobilization of [VO(acac)2]” Clara Pereira, André M. Pereira, Pedro
Quaresma, Pedro B. Tavares, Eulália Pereira, João P. Araújo and Cristina
Freire Dalton Trans., 2010, 39, 2842 – 2854; doi: 10.1039/b920853d
31
“Solution and biological behaviour of enrofloxacin metalloantibiotics: A
route to counteract bacterial resistance?” Raúl Saraiva, Sandra Lopes,
Mariana Ferreira, Florbela Novais, Eulália Pereira, Maria J. Feio and Paula
Gameiro
J.
Inorg.
Biochem.,
2010, 104,
843
–
850;
doi:
10.1016/j.jinorgbio.2010.03.017
32
“One-pot synthesis of triangular gold nanoplates allowing broad and fine
tuning of edge length” Adelaide Miranda, Eliana Malheiro, Elzbieta Skiba,
Pedro Quaresma, Patrícia A. Carvalho, Peter Eaton, Baltazar de Castro,
John A. Shelnutt and Eulália Pereira Nanoscale 2010, 2, 2209-2216; doi:
10.1039/C0NR00337A
33
“New insights into the use of magnetic force microscopy to discriminate
between magnetic and nonmagnetic nanoparticles” Cristina S. Neves,
Pedro Quaresma, Pedro V. Baptista, Patrícia A. Carvalho, João Pedro
Araújo, Eulália Pereira and Peter Eaton Nanotechnology 2010, 21, 305706
(9 p.); doi: 10.1088/0957-4484/21/30/305706
34
“Gold–silver-alloy nanoprobes for one-pot multiplex DNA detection” G.
Doria, M. Larguinho, J. T. Dias, E. Pereira, R. Franco and P. V. Baptista
Nanotechnology 2010, 21, 255101 doi: 10.1088/0957-4484/21/25/255101)
34
“Bionanoconjugates
of
tyrosinase
and
peptide-derivatised
gold
nanoparticles for biosensing of phenolic compounds” J. Cortez, E.
Vorobieva, D. Gralheira, I. Osório, L. Soares, N. Vale, E. Pereira, P.
Gomes, R. Franco J. Nanoparticle Res. 2011, 13, 1101–1113; doi
10.1007/s11051-010-0099-8
35
“Synthesis of gold nanocubes in aqueous solution with remarkable shapeselectivity” Adelaide Miranda, Eliana Malheiro, Peter Eaton, Patrícia A.
Carvalho, Baltazar de Castro and Eulália Pereira J. Porph. Phthal. 2011,
15, 441-448; DOI No: 10.1142/S1088424611003367
36
“Gold nanoparticle-based fluorescence immunoassay for malaria antigen
detection” Bassem S. S. Guirgis, Cláudia Sá e Cunha, Inês Gomes, Miguel
Cavadas, Isabel Silva, Gonçalo Dória, Gregory L. Blatch, Pedro V. Baptista,
Eulália Pereira, Hassan M. E. Azzazy, Maria M. Mota, Miguel Prudêncio,
Ricardo Franco Anal. Bioanal. Chem. 2012, 402, 1019-27; DOI:
10.1007/s00216-011-5489-y
37
“Effect of surface coating on the biodistribution profile of gold nanoparticles
in the rat.” Tiago Morais, Maria Elisa Soares, José Alberto Duarte, Leonor
Soares, Sílvia Maia, Paula Gomes, Eulália Pereira, Sónia Fraga, Helena
Carmo, Maria de Lourdes Bastos Eur. J. Pharm. Biopharm. 2012, 80, 18593; DOI: 10.1016/j.ejpb.2011.09.005
38
"Synthesis, characterization and antibacterial studies of a copper(II)
levofloxacin ternary complex" Isabel Sousa, Vasco Claro, João Lino
Pereira, Ana Luísa Amaral, Luís Cunha-Silva, Baltazar de Castro, Maria J.
Feio, Eulália Pereira, Paula Gameiro J. Inorg. Biochem. 2012, 110, 64–71
39
"Controlled adsorption of cytochrome c to nanostructured gold surfaces."
Inês Gomes, Maria J. Feio, Nuno C. Santo, Peter Eaton, Ana Paula Serro,
Benilde Saramago, Eulália Pereira, Ricardo Franco J. Nanopart. Res.
2012, 12, 1321; DOI: 10.1007/s11051-012-1321-7
40
"Influence of the surface coating on the cytotoxicity and uptake of gold
nanoparticles in human HEPG2 cells." Sónia Fraga, Helena Faria, Maria
Elisa Soares, José Alberto Duarte, Leonor Soares, Eulália Pereira, Cristiana
Costa-Pereira, João Paulo Teixeira, Félix Carvalho, Maria de Lourdes
Bastos, Helena Carmo J. App. Toxicology 2013, 33(10), 1111-1119; DOI:
10.1002/jat.2865
41
"Europium-polyoxometalates
encapsulated
into
silica
nanoparticles:
characterization and photoluminescence studies" Cristina S. Neves, Carlos
M. Granadeiro, Luís Cunha-Silva, Duarte Ananias, Sandra Gago, Gabriel
Feio, Patricia A. Carvalho, Peter Eaton, Salete S. Balula, Eulália Pereira
Eur. J. Inorg. Chem. 2013, 2877-2886; DOI: 10.1002/ejic.201201482
42
"Synthesis, characterization and antibacterial studies of a copper(II)
lomefloxacin ternary complex" Patrícia Fernandes, Isabel Sousa, Luís
Cunha-Silva, Mariana Ferreira, Baltazar de Castro, Eulália F. Pereira, Maria
J. Feio and Paula Gameiro J. Inorg. Biochem. 2014, 131, 21-29; DOI:
dx.doi.org/10.1016/j.jinorgbio.2013.10.013
43
"Use of Gold Nanoparticles as Additives in Protein Crystallization" Diana
Ribeiro, Alina Kulakova, Pedro Quaresma, Eulália Pereira, Cecília
Bonifácio, Maria João Romão, Ricardo Franco, and Ana Luísa Carvalho
Cryst. Growth Des. 2014 DOI: dx.doi.org/10.1021/cg4014398
44
"Star-shaped
magnetite@gold
nanoparticles
for
protein
magnetic
separation and SERS detection." Pedro Quaresma, Inês Osório, Gonçalo
Dória, Patrícia A. Carvalho, Andre M Pereira, Judith Langer, Joao P Araujo,
Isobel Pastoriza-Santos, Luis M. Liz-Marzán, Ricardo Franco, Pedro V
Baptista and Eulália Pereira RSC Adv. 2013, Accepted Manuscript; DOI:
10.1039/C3RA46762G
Book's Chapters:
"Nanoparticles in Molecular Diagnostics" Baptista, P.V.; Doria, G.; Quaresma, P.;
Cavadas, M.; Neves, C. S.; Gomes, I.; Eaton, P.; Pereira, E.; Franco, R. Nanoparticles in
Molecular Diagnostics. In Nanoparticles in Translational Science and Medicine;
Villaverde, A., Ed. Elsevier: London, 2011; Vol. 104, pp. 427-488
"Interactions of gold nanoparticles with proteins" Franco, R. and Pereira, E. in
Encyclopedia of Metalloproteins; Kretsinger, Robert H.; Uversky, Vladimir N.;
Permyakov, Eugene A., Eds. Springer: London, 2013
PATENTS:
“DENDRITIC METAL NANOSTRUCTURES” US 7,374,599, B1, May 20, 2008, J.
A. Shelnutt, C. Medforth, Y. Song, E. Pereira.
“DENDRITIC METAL NANOSTRUCTURES” US 7,785,391, B1, Aug 31, 2010, J.
A. Shelnutt, Y. Song, E. Pereira, C. J. Medforth
ORGANIZATION OF SCIENTIFIC MEETINGS
IV Conferência de Química Inorgânica da Sociedade Portuguesa de Química,
Peniche, Portugal, 1999.