Programa Científico/Scientific Program 2015

Meeting Program (Programa Científico)
NOVEMBER 9th, 2015
NOVEMBER 09th, 2015
14h00 - 20h00 - Registration
16h30 - 17h00 - Meeting Opening
Room A Glória
Welcome & Announcements
17h00 - 18h00 - Samuel Pessoa Conference
Room A Glória
Chair: Sergio Schenkmann
Oral infection by Trypanosoma cruzi
Nobuko Yoshida (Unifesp – São Paulo, SP, Brazil)
20h00 - 20h30 - Reunião do Conselho
Room Baependi
20h30 - 22h30 – Poster Session
Ginásio de Esportes
ODD Numbers/Números ÍMPARES
1
Meeting Program (Programa Científico)
NOVEMBER 10th, 2015
09h00 - 11h00 - OP.01 - Oral Presentations
Room A
BIOLOGY OF HOST-PARASITE INTERACTION
Chair: Fabiana Simão Machado and Angela Hampshire de Carvalho Santos Lopes
Glória
HP001 - IN VIVO IMAGING APPROACHES REVEAL THAT LEISHMANIA VIRULENCE
FACTOR, ISP2, ATTENUATES HOST INNATE RESPONSES ASSOCIATED WITH PARASITE
KILLING
AMY LOUISE GOUNDRY (WELLCOME TRUST CENTRE FOR MOLECULAR
PARASITOLOGY, GLASGOW, REINO UNIDO)
HP002 - ASSOCIATION BETWEEN TGF-β1 POLYMORPHISMS AND SUSCEPTIBILITY TO
CHAGAS DISEASE IN BRAZILIAN PATIENTS
ROBERTO RODRIGUES FERREIRA (FIOCRUZ, RIO DE JANEIRO, RJ, BRASIL)
HP003 - IMPLICATIONS OF LEISHMANIA BRAZILIENSIS PROSTAGLANDIN F2-ALPHA
SYNTHASE EXPRESSION LEVELS IN HOST-PARASITE INTERACTION
ELIZA VANESSA CARNEIRO ALVES FERREIRA (FMRP-USP, RIBEIRAO PRETO, SP,
BRASIL)
HP004 - FULL PROTECTION OF α-GALACTOSYLTRANSFERASE-KNOCKOUT MICE
VACCINATED BY Qβ-αGAL PARTICLE ASSOCIATED WITH ADASP-2 IN EXPERIMENTAL
TRYPANOSOMA CRUZI INFECTION.
MAIRA ARAUJO AZEVEDO (UFMG, BELO HORIZONTE, MG, BRASIL)
HP005 - CCR4-DEPENDENT HOMING OF CD4+CD25+ REGULATORY T CELLS FAVORS
THE L. AMAZONENSIS PERSISTENCE
DJALMA SOUZA LIMA-JUNIOR (FMRP/USP, RIBEIRAO PRETO, SP, BRASIL)
HP006 - TRYPANOSOMA CRUZI: IN VIVO IMAGING OF SINGLE CELLS INSIDE INFECTED
MICE TISSUES
BIANCA RODRIGUES LIMA (UNIFESP, SÃO PAULO, SP, BRASIL)
HP007 - RELATIONSHIP BETWEEN INHIBITORY RECEPTORS EXPRESSION ON CD8+ T
CELLS AND POLYFUNCTIONAL RESPONSE AGAINST TRYPANOSOMA CRUZI ANTIGENS
IN CHRONIC CHAGASIC PATIENTS
PAOLA VERONICA LASSO APRAEZ (PONTIFICIA UNIVERSIDAD JAVERIANA, BOGOTÁ,
COLÔMBIA)
HP008 - PATIENTS WITH ACTIVE VISCERAL LEISHMANIASIS EXHIBIT AN IMBALANCE
BETWEEN SYSTEMIC LEVELS OF PROSTANOIDS AND CYTOKINES
THÉO ARAÚJO-SANTOS (UNIVERSIDADE FEDERAL DO OESTE DA BAHIA, BARREIRAS,
BA, BRASIL)
HP009 - THE ROLE OF MACROPHAGE MIGRATION INHIBITORY FACTOR IN THE
INFECTION INDUCED BY NEOSPORA CANINUM
TAMIRES LOPES SILVA (UFU, UBERLÂNDIA, MG, BRASIL)
HP010 - CEREBRAL VASCULATURE AND COGNITIVE IMPAIRMENT IN ACUTE
TRYPANOSOMA CRUZI INFECTION
UMARU BARRIE (ALBERT EINSTEIN COLLEGE OF MEDICINE, DEPARTMENT OF
PATHOLOGY, BRONX, ESTADOS UNIDOS)
2
Meeting Program (Programa Científico)
NOVEMBER 10th, 2015
09h00 - 11h00 - OP.02 - Oral Presentations
Room B
BIOLOGY OF PROTOZOA AND THEIR VECTORS
Chair: Rossiane Claudia Vommaro and Daniella Castanheira Bartholomeu
Caxambu
PV001 - LUTZOMYIA UMBRATILIS POPULATION CAPTURED IN THE SOUTH OF THE
NEGRO RIVER IS REFRACTORY TO INTERACTION WITH LEISHMANIA GUYANENSIS.
RODRIGO PEDRO SOARES (FUNDAÇÃO OSWALDO CRUZ, BELO HORIZONTE, MG,
BRASIL)
PV002 - USING THE ORFEOME PROJECT AS A TOOL FOR FUNCTIONAL
CHARACTERIZATION OF TRYPANOSOMA CRUZI CANDIDATES PROTEINS
CHRISTIAN MACAGNAN PROBST (ICC - FIOCRUZ, CURITIBA, PR, BRASIL)
PV003 - ANALYSIS OF LEISHMANIA MAJOR OVEREXPRESSING THE EXONUCLEASE-1
HOMOLOGUE
RAÍSSA BERNARDES DA SILVA (UFTM, UBERABA, MG, BRASIL)
PV004 - BIOENERGETIC APPROACH TO HYPOXIC CHALLENGE IN TRYPANOSOMA
CRUZI EPIMASTIGOTES
FRANCIS MONIQUE DE SOUZA SARAIVA (UERJ, RIO DE JANEIRO, RJ, BRASIL)
PV005 - LUTZOMYIA LONGIPALPIS LL5 EMBRYONIC CELL LINE AS A MODEL FOR
INSECT INNATE IMMUNITY STUDIES
DAISY ALINE AZEVEDO-BRITO (IOC-FIOCRUZ, RIO DE JANEIRO, RJ, BRASIL)
PV006 - INORGANIC PHOSPHATE TRANSPORTER IN TOXOPLASMA
CLAUDIA FERNANDA DICK (UFRJ, RIO DE JANEIRO, RJ, BRASIL)
GONDII
PV007 - ELUCIDATING THE ROLE OF MITOCHONDRIAL CALCIUM UNIPORTER (MCU) IN
TRYPANOSOMA CRUZI BY A CRISPR/CAS9 APPROACH
MIGUEL A CHIURILLO (UNIVERSIDADE ESTADUAL DE CAMPINAS (UNICAMP),
CAMPINAS, SP, BRASIL)
PV008 - INVESTIGATION OF THE BIOLOGICAL ROLE OF LEISHMANIA INFANTUM DUALSPECIFICITY TYROSINE-REGULATED KINASE 1 (LINDYRK1) AND EVIDENCE FOR ITS
PARTICIPATION IN PARASITE SPECIFIC PATHWAYS
VINICIUS PINTO COSTA ROCHA (CENTER OF BIOTECHNOLOGY AND CELL THERAPY OF
SÃO RAFAEL HOSPITAL / FIOCRUZ-BAHIA, SALVADOR, BA, BRASIL)
PV009 - CODON USAGE IS THE MAJOR DETERMINANT OF MRNA LEVELS
IN TRYPANOSOMA BRUCEI
DAVID MARK CARRINGTON (UNIVERSITY OF CAMBRIDGE, DEPARTMENT OF
BIOCHEMISTRY, CAMBRIDGE, INGLATERRA)
PV010 - ALTERNATIVE MECHANISMS OF GENE EXPRESSION MODULATION IN T. CRUZI
MUCINS
MARIA DE LOS MILAGROS CAMARA (IIB-INTECH-UNSAM, BUENOS AIRES, ARGENTINA)
3
Meeting Program (Programa Científico)
NOVEMBER 10th, 2015
09h00 - 11h00 - OP.03 - Oral Presentations
TRANSLATIONAL BIOLOGY
Chair: Milton Adriano Pelli de Oliveira and Ricardo Fujiwara
Room C Aiuruoca
TB001 - PHOTODYNAMIC THERAPY USING THE PHOTOSENSITIZER ALUMINUMCLHORIDE PHTALOCYANINE ENTRAPPED IN PLGA NANOCAPSULES (NC-ALPC)
IMPROVES CUTANEOUS LEISHMANIASIS TREATMENT BY SUBCUTANEOUS ROUTE
MILENE VALÉRIA LOPES (UFRJ, RIO DE JANEIRO, RJ, BRASIL)
TB002 - A NEW AROMATIC DIAMIDINE PRODUCES GDNA DAMAGE, DYSKINETOPLASTY
AND ARRESTS TRYPANOSOMA CRUZI CELL CYCLE.
RICHARD MARCEL BRUNO MOREIRA GIRARD (USP, SAO PAULO, SP, BRASIL)
TB003 - GOLDLEISH: NOVEL GOLD(I) PHOSPHINE COMPLEXES ARE HIGHLY ACTIVE
AGAINST ANTIMONY-SENSITIVE AND RESISTANT LEISHMANIA PARASITES
LUIZA GUIMARÃES TUNES (LAB. DE PARASITOLOGIA CELULAR E MOLECULARCPQRR/FIOCRUZ MINAS, BELO HORIZONTE, MG, BRASIL)
TB004
2’-HYDROXYFLAVANONE
EFFECTS
IN
VITRO
AND
IN
VIVO
AGAINST LEISHMANIA AMAZONENSIS
LUIZA FERREIRA DE OLIVEIRA GERVAZONI (FIOCRUZ, RIO DE JANEIRO, RJ, BRASIL)
TB005 - ENCAPSULATION IN PLGA-PVP MICROPARTICLES INCREASES THE LOCAL
EFFICACY OF CHALCONE CH8 AGAINST CUTANEOUS LEISHMANIASIS
ARIANE DE JESUS SOUSA-BATISTA (UFRJ, RIO DE JANEIRO, RJ, BRASIL)
TB006 - GPI FUSED RECOMBINANT PROTEINS: USE IN NANOTECHNOLOGY FOR CELL
TARGETING,
DRUG
DELIVERY
OR
VACCINATION
WESLEY LUZETTI FOTORAN (ICB, SÃO PAULO, SP, BRASIL)
TB007 - ALCOHOL DEHYDROGENASE AND L-TREONINE DEHYDROGENASE ARE
INVOLVED IN THE MECHANISM OF ACTION AND RESISTANCE TO BENZNINDAZOL IN
TRYPANOSOMA CRUZI
ANA MARIA MEJIA (UNIVERSIDAD DE ANTIOQUIA, MEDELLIN, COLÔMBIA)
TB008 - CROTOXIN DERIVED FROM CROTALUS DURISSUS TERRIFICUS STIMULATES
M1 ACTIVATION PROFILE DURING LEISHMANIA AMAZONENSIS INFECTION.
LUIS HENRIQUE SEABRA DE FARIAS (UFPA, BELEM, PA, BRASIL)
TB009 - THE SURFACE LANDSCAPE OF AFRICAN TRYPANOSOMES
CATARINA GADELHA (UNIVERSITY OF NOTTINGHAM, ESTRANGEIRO, REINO UNIDO)
11h00 - 11h30 - COFFEE BREAK
4
Salão de Jogos
Meeting Program (Programa Científico)
NOVEMBER 10th, 2015
11h30 - 12h30 - CO.01 - Conference
Room A Glória
Chair: Luciana de Oliveira Andrade
Intracellular iron acquisition and ROS generation are critical regulators of Leishmania
amazonensis virulence
Norma Windsor Andrews (UMD - College Park, MD, USA)
12h30 - 14h00 - LUNCH
14h00 - 16h00 - RT.01 - RoundTable
ACIDOLCALCISOMES: 20 YEARS STUDYING
Chair: Kildare Rocha Miranda
Room A Glória
RT.1 .001- Twenty years of studies on the structure of Acidocalcisomes
Kildare Rocha Miranda (UFRJ – Rio de Janeiro, RJ, Brazil)
RT.1 .002 - Polyphosphate and acidocalcisomes: organelles conserved from bacteria to human
cells
Roberto Docampo (University of Georgia - Athens, GA, USA)
RT.1 .003 - Initial Characterization of the Acidocalcisomes in Trypanosomes
Anibal Eugenio Vercesi (UNICAMP – Campinas, SP, Brazil)
14h00 - 16h00 - RT.02 - RoundTable
LATEST NEWS ON CONTROL OF GENE EXPRESSION IN
TRYPANOSOMATIDS
Chair: Santuza M. Ribeiro Teixeira
Room B
Caxambu
RT.02.001 - Epigenetic regulation of RNA Pol II transcription termination and gene expression
by DNA modification and histone variants in Trypanosomatids
Robert Sabatini (University of Georgia - Athens, GA , USA)
RT.02.002 - A DEAD-box RNA helicase of the Dde1/DDX3 subfamily plays a central role in
mitochondrial quality control and the response to stress in Leishmania
Barbara Papadoupoulus (Laval University – CRCHU – Quebec, Canada)
RT.02.003 - The role of heme in protein expression in Trypanosoma cruzi
Sergio Schenkman (UNIFESP – São Paulo, SP, Brazil)
RT.02.004 - Networks of gene expression control in trypanosomes
Christine Clayton (Heidelberg University – ZMBH - Heidelberg, Germany)
5
Meeting Program (Programa Científico)
NOVEMBER 10th, 2015
14h00 - 16h00 - RT.03 - RoundTable
MOLECULAR INTERACTIONS BETWEEN PARASITES AND
VECTORS
Chair: Rodrigo Pedro Pinto Soares
Room C Aiuruoca
RT.03.001 - Genome-wide analysis of Rhodnius prolixus gut gene expression: influences of the
blood meal and Trypanosome infection
Pedro Lagerblad de Oliveira (UFRJ – Rio de Janeiro, RJ, Brazil)
RT.03.002 - Gp63 is one of the molecules responsible for trypanosomatid-insect interaction
Cláudia Masini D'Ávila-Levy (FIOCRUZ-IOC - Rio de Janeiro, RJ, Brazil)
RT.03.003 - Sand fly-Leishmania interaction and vaccine development
Iliano Vieira Coutinho-Abreu (NIH - Rockville, MD, USA)
RT.03.004 - Sand fly salivary antigens and antibody response in bitten hosts: screening of
domestic animals exposed to Old-World vectors of visceral leishmaniases
Petr Volf (Charles University in Prague – Prague, Czech Republic)
16h00 - 16h30 - COFFEE BREAK
16h30 - 17h00 - MC.01 - Mini Conference
Salão de Jogos
Room A
Glória
Chair: Ariel Mariano Silber
A Glycoconjugate Vaccine Elicits B and T Cell-Dependent Protection Against Experimental
Trypanosoma cruzi Infection
Igor Correia de Almeida (University of Texas at El Paso – El passo, TX, USA)
16h30 - 17h00 - MC.02 - Mini Conference
Room B
Caxambu
Chair: Elvira Maria Saraiva
Innate Immune Response in the Control and Pathology of Leishmania braziliensis Infection
Edgar Marcelino de Carvalho Filho (UFBA – Salvador, BA, Brazil)
16h30 - 17h00 - MC.03 - Mini Conference
Room C Aiuruoca
Chair: Angela Kaysel Cruz
Functional genomics of drug resistance in Leishmania
Marc Ouellette (Canadian Institutes of Health Research – Quebec, Canada)
6
Meeting Program (Programa Científico)
NOVEMBER 10th, 2015
17h00 - 17h30 - MC.04 - Mini Conference
Room A
Glória
Chair: Samuel Goldenberg
Parasite persistence mechanisms in Trypanosoma cruzi infection and Chagas` disease
Rick L. Tarleton (University of Georgia – Athens, GA, USA)
17h00 - 17h30 - MC.05 - Mini Conference
Room B
Caxambu
Chair: Maria Cristina Machado Motta
Neglected pathways hidden behind glycolysis in bloodstream trypanosomes
Frédéric Bringaud (Université Bordeaux Segalen – Bordeaux, France)
17h00 - 17h30 - MC.06 - Mini Conference
Room C
Aiuruoca
Chair: Maria Julia Manso Alves
Trypanosoma cruzi extracellular amastigotes and the host cell: recent findings on host actin
cytoskeleton and parasite microvesicles
Renato Arruda Mortara (UNIFESP – São Paulo, SP, Brazil)
17h30 - 18h30 - CO.02 - Conference
Room A Glória
Chair: Narcisa Leal da Cunha-e-Silva
Cell morphogenesis, shape and pathogenicity in kinetoplastid parasites
Keith Gull (University of Oxford – Oxford, UK)
18h30 - 19h30 - Plenary Session of SBPz
Room B Caxambu
20h30 - 22h30 - Poster Session
Ginásio de Esportes
EVEN Numbers/Números PARES
7
Meeting Program (Programa Científico)
NOVEMBER 11th, 2015
09h00 - 11h00 - OP.04 - Oral Presentations
BIOLOGY OF HOST-PARASITE INTERACTION
Chair: Luiz Ricardo Orsini Tosi and Lucile Floeter-Winter
Room A
Glória
HP011 - MITOCHONDRIAL DYSFUNCTION AND REACTIVE OXYGEN SPECIES IN
NEONATAL PRIMARY CARDIOMYOCYTES: RELATION TO T. CRUZI INTRACELLULAR
DEVELOPMENT
PATRÍCIA PEREIRA SILVA (UFMG, BELO HORIZONTE, MG, BRASIL)
HP012 - TRANSCRIPTOMIC PROFILE OF HUMAN CELLS STIMULATED WITH SALIVA
FROM LU. INTERMEDIA OR FROM LU. LONGIPALPIS, VECTORS OF LEISHMANIASIS IN
BRAZIL.
REBECCA P CURVELO (CPQGM-FIOCRUZ, SALVADOR, BA, BRASIL)
HP013 - TRYPANOSOMA CRUZI ISOLATES FROM DIFFERENT CHAGAS DISEASE
CLINICAL FORMS HAVE A DISTINCT PROFILE REGARDING RESISTANCE TO OXIDATIVE
STRESS AND REACTIVE OXYGEN SPECIES PRODUCTION
FERNANDA RAMOS GADELHA (UNICAMP, CAMPINAS, SP, BRASIL)
HP014 - THE ROLE OF INTEGRATED ENDOPLASMIC RETICULUM STRESS RESPONSE IN
THE PATHOGENESIS OF LEISHMANIA AMAZONENSIS
KARINA LUIZA DIAS TEIXEIRA (UFRJ, RIO DE JANEIRO, RJ, BRASIL)
HP015 - ROLE OF CXCR3 CHEMOKINE RECEPTOR FOR T-CELL MEDIATED PROTECTIVE
IMMUNITY ELICITED BY HETEROLOGOUS PRIME-BOOST VACCINATION AGAINST A
SYSTEMIC PARASITIC INFECTION.
CAMILA PONTES FERREIRA (UNIFESP, SAO PAULO, SP, BRASIL)
HP016 - ROLE OF PD-1/PD-L1 IN THE INDUCTION OF REGULATORY T CELLS DURING
LEISHMANIA AMAZONENSIS INFECTION
ALESSANDRA MARCIA DA FONSECA MARTINS (UFRJ, RIO DE JANEIRO, RJ, BRASIL)
HP017 - CHARACTERIZATION OF THE INFECTION OF MOUSE NEUROSPHERES
BY TOXOPLASMA GONDII AS AN IN VITRO MODEL OF CONGENITAL TOXOPLASMOSIS.
DANIEL ADESSE (LABORATÓRIO DE BIOLOGIA ESTRUTURAL, FIOCRUZ, RIO DE
JANEIRO, RJ, BRASIL)
HP018 - ABSENCE OF INDIGENOUS MICROBIOTA IMPAIRS MICROBICIDAL ACTIVITY OF
MACROPHAGES
MATEUS EUSTÁQUIO DE MOURA LOPES (UFMG, BELO HORIZONTE, MG, BRASIL)
HP019 - LACK OF SAPA DOMAIN OF TRANS-SIALIDASES AS A FACTOR THAT
CONTRIBUTE TO THE ATTENUATED PHENOTYPE OF THE CLONE CL-14
OF TRYPANOSOMA CRUZI
CAROLINE JUNQUEIRA (CPQRR/ FIOCRUZ, BELO HORIZONTE, MG, BRASIL)
HP020 - CIRCULATING NEUTROPHILS PRESENT A HEIGHTENED INFLAMMATORY
STATE DURING ACTIVE CUTANEOUS LEISHMANIASIS
JACILARA ALEXANDRINO CONCEIÇÃO (UFBA, SALVADOR, BA, BRASIL)
8
Meeting Program (Programa Científico)
NOVEMBER 11th, 2015
09h00 - 11h00 - OP.05 - Oral Presentations
BIOLOGY OF PROTOZOA AND THEIR VECTORS
Chair: Luis Carlos Crocco Afonso and Silvane Maria Fonseca Murta
Room B
Caxambu
PV011 - L. AMAZONENSIS METABOLOMICS ASSOCIATED WITH LOSS OF VIRULENCE
AND IN VIVO CELL DIFFERENTIATION
FREDERICO CREPALDI NASCIMENTO (FACULDADE DE FARMACIA - UFMG, BELO
HORIZONTE, MG, BRASIL)
PV012 - PROTEOMIC ANALYSIS OF EXTRACELLULAR VESICLES RELEASED
FROM TRYPANOSOMA CRUZI DURING METACYCLOGENESIS
MARIA LUIZA ZARDO (INSTITUTO CARLOS CHAGAS, CURITIBA, PR, BRASIL)
PV013 - ASSESSING THE GUT MICROBIAL DIVERSITY OF FIELD AEDES AEGYPTI
MOSQUITOES
JAQUELINE JARUSEVICIUS (UNESP, BOTUCATU, SP, BRASIL)
PV014 - CHARACTERIZATION OF TELOMERIC REPEAT-CONTAINING RNA (TERRA)
EXPRESSION IN LEISHMANIA SPP
EDNA GICELA ORTIZ MOREA (INSTITUTE OF BIOSCIENCES, UNESP-BOTUCATU,
BOTUCATU, SP, BRASIL)
PV015 - OVEREXPRESSION OF GLUCOKINASE IN TRYPANOSOMA
EPIMASTIGOTES IS TOXIC
MELISA GUALDRON LOPEZ (UFMG, BELO HORIZONTE, MG, BRASIL)
CRUZI
PV016 - TRYPANOSOMA RANGELI INFECTION MODULATES ANTIMICROBIAL PEPTIDES
MRNA LEVELS IN RHODNIUS PROLIXUS MIDGUT AND FAT BODY
CECÍLIA STAHL VIEIRA (INSTITUTO OSWALDO CRUZ, RIO DE JANEIRO, RJ, BRASIL)
PV017 - THE INTRASPECIFIC POLYMORPHISMS IN THE LIPOPHOSPHOGLYCAN
OF LEISHMANIA AMAZONENSIS DOES NOT INFLUENCE IN THEIR INTERACTION WITH
THE SAND FLY VECTOR LUTZOMYIA MIGONEI
PAULA MONALISA NOGUEIRA (UNIVERSIDADE FEDERAL DE MINAS GERAIS, BELO
HORIZONTE, MG, BRASIL)
PV018 - METACYCLOGENESIS OF TRYPANOSOMA CRUZI INCLUDES STARVATIONINDUCED TRANSIENT ACCUMULATION OF MITOCHONDRIAL GENE TRANSCRIPTS
AUBIE KAY SHAW (UNIVERSITY OF MINNESOTA, DULUTH, ESTADOS UNIDOS)
PV019 - DISSECTING SOCIAL MOTILITY IN AFRICAN TRYPANOSOMES BY A RNA-SEQ
TRANSCRIPTOME ANALYSIS
RINA KIM (UNIVERSITY OF CALIFORNIA, LOS ANGELES, ESTADOS UNIDOS)
PV020 - THE ROLE OF RBP9 AND RBP10 IN THE MODULATION OF GENE EXPRESSION
IN TRYPANOSOMA CRUZI
HELISA HELENA WIPPEL (ICC FIOCRUZ PR, SAO JOSE DOS PINHAIS, PR, BRASIL)
9
Meeting Program (Programa Científico)
NOVEMBER 11th, 2015
09h00 - 11h00 - OP.06 - Oral Presentations
TRANSLATIONAL BIOLOGY
Chair: Edmundo Carlos Grisard and Osvaldo Pompilio de Melo Neto
Room C Aiuruoca
TB010 - IDENTIFICATION OF NEW DRUGS AGAINST CHAGAS DISEASE THROUGH A
CHEMOGENOMICS DRUG REPOSITIONING STRATEGY
WANESSA MOREIRA GOES (UFG, GOIÂNIA, GO, BRASIL)
TB011 - DRUG TARGETS AND INHIBITORS OF INOSITOL PHOSPHATE METABOLISM IN
KINETOPLASTID PARASITES
IGOR CESTARI (CENTER FOR INFECTIOUS DISEASE RESEARCH, SEATTLE, ESTADOS
UNIDOS)
TB012 - DEVELOPMENT OF A PROTOTYPE KIT FOR MOLECULAR DIAGNOSIS AND
PARASITE LOAD QUANTIFICATION OF PATIENTS WITH CHAGAS DISEASE
LETICIA ROCHA QUINTINO SOUZA (FUNDAÇÃO OSWALDO CRUZ, RIO DE JANEIRO, RJ,
BRASIL)
TB013 - A HIGH CONTENT ANALYSIS FOCUSING ON A COMPOUND ABLE OF
INTERFERING WITH INTRACELLULAR DEVELOPMENT OF TRYPANOSOMA CRUZI
ADALBERTO MIGUEL DE ARAÚJO JÚNIOR (UNIFESP - DMIP, CAMPINAS, SP, BRASIL)
TB014 - TESTING PROTEIN RECOGNIZED BY RECOVERED VISCERAL LEISHMANIASIS
PATIENTS IN EXPERIMENTAL MODEL OF CUTANEOUS LEISHMANIASIS.
LAURA RAMÍREZ (CPQGM/FIOCRUZ, SALVADOR, BA, BRASIL)
TB015 - BACTERIAL CELLULOSE BIO-CURATIVES CONTAINING DETC FOR THE TOPICAL
TREATMENT OF CUTANEOUS LEISHMANIASIS CAUSED BY LEISHMANIA BRAZILIENSIS
FABIANA SANTANA CELES (UNIVERSIDADE FEDERAL DA BAHIA, SALVADOR, BA,
BRASIL)
TB016 - EFFECT OF CALPAIN INHIBITOR MDL28170 ON GROWTH, MACROPHAGE
INTERACTION AND PEPTIDASES EXPRESSION OF LEISHMANIA BRAZILIENSIS
VITOR ENNES VIDAL (FIOCRUZ, RIO DE JANEIRO, RJ, BRASIL)
TB017 - EVALUATION OF CASPASES AND TREM IN SKIN BYOPSIES OF LOCALIZED
LESIONS FROM PATIENTS WITH TEGUMENTARY LEISHMANIASIS IN ENDEMIC AREA IN
THE STATE OF BAHIA, BRAZIL
DANIEL FERREIRA FEIJÓ (CPQGM - FIOCRUZ/BAHIA, SALVADOR, BA, BRASIL)
TB018 - THE COST EFFECTIVENESS OF METHODS TO EVALUATE DRUG ACTIVITY
AGAINST PLASMODIUM FALCIPARUM IN VITRO
PEDRO AUGUSTO ALVES RIBEIRO (CPQRR/FIOCRUZ, BELO HORIZONTE, MG, BRASIL)
11h00 - 11h30 - COFFEE BREAK
10
Salão de Jogos
Meeting Program (Programa Científico)
NOVEMBER 11th, 2015
11h30 - 12h30 - CO.03 - Conference
Room A Glória
Chair: Leda Quercia Vieira
The biology of mating in Leishmania
David L. Sacks (NIAID - Bethesda, MD, USA)
12h30 - 14h00 - LUNCH
14h00 - 16h00 - RT.04 – Round Table
IMMUNOLOGY OF PROTOZOAN INFECTIONS
Chair: Walderez O. Dutra
Room A Glória
RT.04.001 - Host responses in the clinical and therapeutic outcomes of L. V. panamensis
infection
Maria Adelaida Gómez (CIDEIM – Cali, Colombia)
RT.04.002 - Contribution of mononuclear phagocytes to inflammatory response in cutaneous
leishmaniasis
Lucas Pedreira de Carvalho (UFBA – Salvador, BA, Brazil)
RT.04.003 - Challenges in the Approach to Treating Infection Trypanosoma cruzi
David Engman (Northwestern University – Chicago, IL, USA)
RT.04.004 - MiRNA Profile in Trypanosoma cruzi Infection: Association with Pathology,
Development and Immune Response
Ludmila Rodrigues Pinto Ferreira (FMUSP – São Paulo, SP, Brazil)
14h00 - 16h00 - RT.05 – Round Table
BIOLOGY OF APICOMPLEXA PARASITES
Chair: Renato Augusto DaMatta
Room B
Caxambu
RT.05.001 - Toxoplasma effector GRA26 activates the chromatin repressor EZH2 to dampen
the host IL-1β-mediated inflammatory response
Mohamed-Ali Hakimi (Joseph Fourier University - Saint-Martin-d'Hères, France)
RT.05.002 - Toxoplasma modulation of the host cell
Jeroen Saeij (University of California - Davis, CA, USA)
RT.05.003 - Genetic Exchange, Surface Antigens and Inflammasome Sensors Activated by
Protozoan Parasites
Michael Grigg (NIH – NIAID - Bethesda, MD, USA)
RT.05.004 - Research Priorities and Unmet needs in Clinical Toxoplasmosis
Rubens Belfort (UNIFESP, São Paulo, SP, Brasil)
11
Meeting Program (Programa Científico)
NOVEMBER 11th, 2015
14h00 - 16h00 - RT.06 - RoundTable
TRANSLATIONAL RESEARCH OF PROTOZOAN PARASITES
Chair: Jeffrey J. Shaw
Room C Aiuruoca
RT.06.001 - Translational research, from models to humans
Israel Molina Romero (VHEBRON – Barcelona, Spain)
RT.06.002 - Re-education of the immune system has a beneficial effect on experimental
Chagas' heart disease: unveiling targets for therapy
Joseli Lannes-Vieira (FIOCRUZ – IOC - Rio de Janeiro, RJ, Brazil)
RT.06.003- The Unfolding Story of Tamoxifen in Leishmaniasis Chemotherapy
Silvia Reni Bortolin Uliana (USP - ICB – São Paulo, SP, Brazil)
RT.06.004 - Researching and developing new antimalarials: where are we going?
Antoniana Ursine Krettli (FIOCRUZ – CPQRR - Belo Horizonte, MG, Brasil)
16h00 - 16h30 - COFFEE BREAK
Salão de Jogos
16h30 - 17h00 - MC.07 - Mini Conference
Room A
Glória
Chair: Lucile Maria Floeter-Winter
Studies of the Leishmania dsRNA virus LRV1 in animal models and human disease
Stephen M. Beverley (Washington University School of Medicine – St. Louis, MO, USA)
16h30 - 17h00 - MC.08 - Mini Conference
Room B
Caxambu
Chair: Renata Rosito Tonelli
Trypanosoma cruzi Phenotypic Diversity: a role for mucin-like molecules
Carlos A. Buscaglia (UNSAM – San Martin, Argentina)
16h30 - 17h00 - MC.09 - Mini Conference
Room C Aiuruoca
Chair: Santuza M. Ribeiro Teixeira
To infinity and beyond: on the diversity and distribution of Toxoplasma gondii
Judith Smith (BSP President - Bedford, UK)
12
Meeting Program (Programa Científico)
NOVEMBER 11th, 2015
17h00 - 17h30 - MC.10 - Mini Conference
Room A
Glória
Chair: Ana Paula Salles Moura Fernandes
Meeting the Challenge of Developing Drugs for Neglected Tropical Diseases
James McKerrow (UCSD - La Jolla, CA, USA)
17h00 - 17h30 - MC.11 - Mini Conference
Room B
Caxambu
Chair: Maria Carolina Elias
Cellular and molecular biology of Leishmania spp. telomeres: insights about the evolutivon of
telomere maintenance
Maria Isabel Nogueira Cano (UNESP – IB - Botucatu, SP, Brazil)
17h00 - 17h30 - MC.12 - Mini Conference
Room C
Aiuruoca
Chair: Yara Maria Traub-Cseko
Leishmania's exosomes: A new virulence factor to consider
Martin Olivier (McGill - Montreal, Quebec, Canada)
17h30 - 18h30 - CC - Conference
Room A Glória
Chair: Walter Colli
Innate Resistance against Toxoplasma gondii: An Evolutionary Tale of Mice, Cats, and Men
Ricardo Tostes Gazzinelli (Fiocruz-CPqRR – Belo Horizonte, MG, Brazil)
18h30 - 19h30 Brainstorm
21h30 - 22h30
Zigman Brener Awards and Closing Remarks
Room B Caxambu
Room A
Glória
13