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DEFESA DE DISSERTAÇÃO DE MESTRADO Alun(o)a Jaqueline Stecanela Mandelli Orientador Prof. Carlos Renato Rambo, Dr. –Eng. EEL/UFSC Coorientadora Prof. Janice Koepp, Dr. Farmaco/UFSC Data 13 de Dezembro de 2012 Local Sala B 6 – Bloco B do Departamento de Engenharia Mecânica Horário 09:00 horas Prof. Carlos Renato Rambo, Dr. –Eng. EEL/UFSC - Presidente Banca Prof. Guilherme Mariz de Oliveira Barra, Dr. -Eng. EMC/UFSC- Membro Prof. Luismar Marques Porto, Dr. –Eng. ENQ/UFSC - Membro Externo Prof. Jefferson Luiz Brun Marques, Ph. D, EEL/UFSC – Membro Externo Prof. Marcio Celso Fredel, Dr. –Ing. ECM/UFSC – Suplente Janaina Accordi Junkes, Dr. -Eng. EMC/UFSC – Suplente Título “Inkjet printing of flexible organic electrodes for tissue engineering applications” RESUMO Inkjet printing has been demonstrated to be able to print all materials required for integrated circuits at low costs when compared to conventional silicon processing. With the advent of organic electronics, a wide range of materials became available and the fabrication of devices with unique properties for interfacing with biology is now possible. One important example is the use of conducting polymer coatings on metal electrodes that are implanted in the central nervous system, which provides electrical stimulation of neurons. This work reports on the fabrication of biocompatible organic devices by means of inkjet printing. The devices were fabricated on Parylene C (PaC), a biocompatible, flexible polymer substrate. The contact tracks were printed using a silver nanoparticle ink, while the active sites were inkjet printed using a poly (3,4ethylenedioxythiophene)/polystyrene sulfonate (PEDOT:PSS) solution. To insulate the final device, a polyimide ink was used to print a thick film, leaving small opened windows upon the active sites. Electrical characterization of the final device and evaluation of its interface with biology (cells culture essays) were performed. The results show that inexpensive and biocompatible devices can be produced by direct writing without any pre-patterning or self-alignment techniques using organic inks. Palavra Chave: Inkjet Printing. Organic Electrodes. Tissue Engineering.