INSTITUTO DE PSIQUIATRIA – IPUB/UFRJ Programa de Pós
Transcrição
INSTITUTO DE PSIQUIATRIA – IPUB/UFRJ Programa de Pós
INSTITUTO DE PSIQUIATRIA – IPUB/UFRJ Programa de Pós-Graduação em Psiquiatria e Saúde Mental - PROPSAM CURSO DE FÉRIAS Coordenação no PROPSAM: professores Leonardo Fontenelle e Gabriela Menezes Disciplina com 45 horas de carga horária para Mestrandos e Doutorandos Aberta para ouvintes com direito à Certificado Inscrições por e-mail ([email protected]) até 12/07/2012 às 13:00 h Neurobiologia dos Processos Volitivos Coordenador: Prof. Murat Yücel (Melbourne Neuropsychiatry Centre & Melbourne Health, University of Melbourne, Australia), Dr. Ben J. Harrison (Melbourne Neuropsychiatry Centre & Melbourne Health, University of Melbourne, Australia), Dr. Hironobu Fijuwara (Department of Molecular Neuroimaging, Molecular Imaging Center, National Institute of Radiological Sciences) Período: 13 a 31 de Julho de 2012 (09:00 às 13:00) Auditórios Leme Lopes & William Asmar Aulas serão ministradas em inglês Ementa: Este curso reúne uma série de aulas independentes que pretendem fornecer uma visão geral sobre os aspectos neurobiológicos de transtornos psiquiátricos caracterizados por prejuízos dos processos volitivos (e.g. abuso de substâncias, transtorno obsessivo-compulsivo e dependências comportamentais) e seu impacto sobre a cognição e comportamento. 1) Drug Use, Teenage Brain Development & Mental Health (overview cognitive/MRI findings in inhalants, cannabis, heroin and its implications for mental health) 2) The impact of cannabis use on cognitive functioning and brain structure: implications for understanding the neural basis of psychosis and its clinical implications. 3) PET imaging in internet addiction 4) PET imaging in psychiatric disorders 5) Brain corticostriatal network alterations in OCD: Summary of past & current findings Mês Sexta Terça Terça Quinta Terça Julho 13 17 24 26 31 Horário: 9 Leme William William Leme William às 13h Lopes* Asmar Asmar Lopes Asmar Nota: * Aula no Centro de Estudos (início às 10:30h) 2 BIOGRAFIAS Murat Yücel (Melbourne Neuropsychiatry Centre & Melbourne Health, University of Melbourne, Australia): Professor Yücel’s is an authority in the area of biological psychiatry and neurobiology of drug addiction. His research spans two main themes: (i) Understanding the neural, psychological and biochemical basis of the “compulsive” or “addictive” behaviours seen across substance related disorders, as well as psychiatric and neurological disorders (e.g., obsessive-compulsive disorder, schizophrenia, and Parkinson’s disease), and: (ii) Understanding the links between heavy cannabis use, the brain and mental health (especially psychosis). Professor Yücel has an exceptional track record of research and publication, both in terms of quantity and quality. He has received local, national, and international media attention and been extremely well cited relative to the number of years this work has been published drawing over 4000 citations (~1200 last year alone). Over his research career, he has been involved in obtaining >$18 million project funding as a Chief Investigator on 3 large international and 15 large national (NHMRC, ARC) grants. Currently, he is involved in managing >$5 million in project grant funding and has >160 publications on these and related topics. Ben J Harrison (Mebourne Neuropsychiatry Centre & Melbourne Health, University of Melbourne, Australia): Dr. Ben Harrison is a NHMRC Clinical Research Fellow (2010-2014). He co-leads the Affective Neuropsychiatry group at MNC and is member of the Centre’s Executive Committee. His work principally involves the use of functional neuroimaging techniques to study the brain basis of emotional disturbance in mood and anxiety disorders, including major depression, social anxiety disorder and obsessive-compulsive disorder. Related to this work, he has a basic interest in the characterising the functional role of brain corticostriatal, central autonomic and “default-mode network” systems. Dr. Ben Harrison has an long track record of research and publication, drawing over 1000 citations. He participates in several competitively-funded national and international research projects, in addition to leading a current NHMRC Project Grant. He supervises post-doctoral fellows and PhD students. In September 2012, he will commence an appointment as Senior Research Fellow. Hironobu Fujiwara (Department of Molecular Neuroimaging, Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan): Currently, Dr. Fujiwara is a researcher at Prof. Tetsuya Suhara's laboratory, at the Molecular Imaging Center, in Chiba, Japan. He has published extensively on the neuroanatomical correlates of impaired social cognition in schizophrenia. Currently, his research focus is on the elucidation of the pathophysiology of neuropsychiatric diseases, e.g., addiction, schizophrenia, depression, and dementia, using PET and MRI. PET technique with molecular probes enables us to measure the function of neurotransmission in humans. Activation studies using MRI with psychological and physiological tasks allow the investigation of regional neural function. The aim of Dr. Fujiwara's research work is the establishment of bio-markers for early diagnosis and evaluation of treatment using PET combined with MRI in clinical studies. REFERÊNCIAS Yücel M, Bora E, Lubman DI, Solowij N, Brewer WJ, Cotton SM, Conus P, Takagi MJ, Fornito A, Wood SJ, McGorry PD, Pantelis C. The impact of cannabis use on cognitive functioning in patients with schizophrenia: a meta-analysis of existing findings and new data in a first-episode sample. Schizophr Bull. 2012 Mar;38(2):316-30. Harrison BJ, Soriano-Mas C, Pujol J, Ortiz H, López-Solà M, Hernández-Ribas R, 3 Deus J, Alonso P, Yücel M, Pantelis C, Menchon JM, Cardoner N. Altered corticostriatal functional connectivity in obsessive-compulsive disorder. Arch Gen Psychiatry. 2009 Nov;66(11):1189-200. Fontenelle LF, Oostermeijer S, Harrison BJ, Pantelis C, Yücel M. Obsessive-compulsive disorder, impulse control disorders and drug addiction: common features and potential treatments. Drugs. 2011 May 7;71(7):827-40. Bora E, Harrison BJ, Fornito A, Cocchi L, Pujol J, Fontenelle LF, Velakoulis D, Pantelis C, Yücel M. White matter microstructure in patients with obsessive-compulsive disorder. J Psychiatry Neurosci. 2011 Jan;36(1):42-6. Fontenelle LF, Harrison BJ, Pujol J, Davey CG, Fornito A, Bora E, Pantelis C, Yücel M. Brain functional connectivity during induced sadness in patients with obsessive-compulsive disorder. J Psychiatry Neurosci. 2012 Jul;37(4):231-40. Kubota M, Miyata J, Yoshida H, Hirao K, Fujiwara H, Kawada R, Fujimoto S, Tanaka Y, Sasamoto A, Sawamoto N, Fukuyama H, Murai T. Age-related cortical thinning in schizophrenia. Schizophr Res. 2011 Jan;125(1):21-9.
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