Supplementary Tables 1 and 2

Supplementary Table S1. Levels of autoantibody (auto-Ab) and IgA in saliva samples
Levels of antibody (mean±SD, median, range)
Groups (n)
Healthy control (131)
LR-OPMD (42)
HR-OPMD (44)
p53
auto-Aba
survivin
auto-Aba
CK-8
auto-Aba
Hsp60
auto-Aba
Recurrent OSCC (20)
IgAb
2161±1995,
1406±1657,
1777±2868,
942±839,
604±587,
1.82±0.82,
1470, 114-10379
834, 41-9555
914, 92-20603
727, 42-4043
432, 53-3591
1.91, 0.06-3.14
1816±1187,
1803, 309-5287
1247±888,
619±491,
1.94±0.73,
988, 212-3428 481, 170-2675 2.16, 0.47-3.14
2600±2380,
1731±1730,
1709, 554-10764 1329, 208-9438
3711±3993,
2461±3410,
2478±3549,
1436±1298,
2069, 276-14101 1540, 78-19103 1400, 204-17835 1028, 86-5737
Primary OSCC (111)
RPLP0
auto-Aba
4419±5901,
2890±5286,
2638±4765,
1667±2849,
889±950,
1.86±0.78,
499, 94-4462
2.00, 0.34-3.14
1458±3082,
2.15±0.83,
2107, 83-30726
1342, 24-32123 1223, 138-29750 939, 17-27102 584, 35-23305 2.42, 0.04-3.14
4786±6094,
2680, 140-21799
2485±3476,
1001, 18-11910
1930±2357,
956, 116-8564
1522±1879,
1005, 26-6832
1275±1975,
509, 38-7703
1.64±1.15,
1.53, 0.04-3.14
a
Data are shown as mean±SD, median, and range of MFI.
b
Data are shown as mean±SD, median, and range of optical density at 450nm with 540nm as the wavelength correction.
Supplementary Table S2. Estimated odds ratio (OR) with and without adjusting for co-variables.
Comparison
Marker
Healthy control vs. cancer
OR (95% CI)
p value
OR (95% CI)
p value
anti-p53
1.002 (1.001, 1.003)
0.0003
1.002 (1.001, 1.002)
0.0027
anti-survivin
1.002 (1.000, 1.003)
0.0065
1.002 (1.000, 1.003)
0.0202
anti-CK8
1.001 (1.000, 1.001)
0.1230
1.001 (1.000, 1.002)
0.0854
anti-Hsp60
1.004 (1.001, 1.006)
0.0023
1.005 (1.002, 1.008)
0.0024
anti-RPLP0
1.006 (1.002, 1.009)
0.0006
1.006 (1.002, 1.010)
0.0032
1.001 (1.000, 1.002)
0.0196
1.001 (1.000, 1.002)
0.0223
anti-survivin
1.002 (1.000, 1.003)
0.0194
1.002 (1.000, 1.003)
0.0224
anti-CK8
1.002 (1.000, 1.003)
0.0453
1.002 (1.000, 1.000)
0.0531
anti-Hsp60
1.004 (1.001, 1.007)
0.0094
1.004 (1.001, 1.007)
0.0117
anti-RPLP0
1.003 (1.000, 1.006)
0.0399
1.003 (1.000, 1.006)
0.0498
Well vs. moderate differentiation anti-p53
a
Co-variable adjustmenta
No adjustment
Multivariate analysis was adjusted with age, tobacco, betel nut chewing, and alcohol drinking in the case-control
comparisons. The overall stage (stage I-II vs. III-IV) was considered as a co-variable to be adjusted in comparisons
between well and moderately differentiated OSCCs.