AIM 2014-2-final-dubravko.indd
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AIM 2014-2-final-dubravko.indd
120 A Comparative Study of the Proposed Models for the Components of the National Health Information System doi: 10.5455/aim.2014.22.120-122 ORIGINAL PAPER ACTA INFORM MED. 2014 APR 22(2): 120-122 Received: 17 December 2013 • Accepted: 28 Januar 2014 © AVICENA 2014 Proposed Use of the Computer as a Tool to Aid Analysis of Properties of Materials in Fixators of Spine Antonio Santos1, Fernando Moreira2 Departamento de Biotecnologia, Universidade Federal de São Carlos, São Carlos, São Paulo, Brasil1 Departamento de Biotecnologia, Universidade Federal de São Carlos, São Carlos, São Paulo, Brasil2 Corresponding author: Antonio Santos. Departamento de Biotecnologia, Universidade Federal de São Carlos, São Carlos, São Paulo, Brasil. E-mail: ams@ sc.usp.br1. ABSTRACT Withobjectiveofanalyzingthemechanicalbehavioroftheinternalfixatorsofspineandofthebonystructure,thepiecesandthegroup weremade(itstructuresbonyxinternalfixator)withtheaidasoftwareofsolidmodeling.Thematerialsusedintherehearsalshadbeen thetitanium,nowinthemarketandacastoroilpolyurethanedestinedtothedevelopmentofyouimplantbony. Key words:castoroil,internalfixators,simulatedandstructuresbony.. 1. IN T RODUC T ION From beginning to end of life, the skeletal system adjusts to maintain the structural integrity of bones, which in daily life is subject to various conditions of mechanical loading. Consequently, the structural response, in part, due to the past history of loads imposed on the skeleton, the need for this, and the anticipation of future demands (1). In orthopedic practice, often faced with situations where there is continuity of bone changes (segmental bone loss or fractures), especially because of the highenergy trauma, tumors, infections and congenital malformations (2). There is a continuous deformation depending on the time of load application. The main element in the ability of the vertebra to support load is spongy. The cortical bone contributes 10% of the compressive strength and bone with 50% (3). The fixators of the spine for correction of conditions is to make the injured segment disk using screws and rods appropriate way to extend a force to be applied. Currently the fixators, have been used not only for stabilization of fractures, but also stretches pain and bone compressor, conveyor segments or fragments of bone and reducing fracture (4). However, little is known about the mechanical behavior of these structures and what is the correlation between the choice of the system and assembly, the type of disease being treated and the complications that can set the (5). The increase in applications and the number of handset models available and studies the influence of effort on bone demanded investigation of the mechanical characteristics of these devices, and different ORIGINAL PAPER / ACTA INFORM MED. 2014 APR 22(2): 120-122 mounting, in order to adapt them to clinical applications desired (6). Most of the fasteners found on the market for clinical tract, have been used in studies of simulations is made of titanium (7). In Brazil, the study of biomechanics of the column began in 1987 (8). There are three types of biomechanical studies of the spine: tests of strength, endurance and stability (9). Strength tests are made by applying a progressive force majeure, until there is structural failure. The fatigue is done by repeated application of a load until structural failure occurs and the stability is given from the application of different loads with different meanings (10). With a view to facilitate the analysis of specific points of three-dimensional models created the finite element method (FEM), which is the subdivision of the problem in small regions (elements) where the field behavior of interest may approximate the functions simple, such as polynomials or harmonic functions. One reason for this simplification is the reduction of unknowns in the system of equations and consequently reducing the computational time. In 1984, the Group of Analytical Chemistry and Polymer Technology, University of São Paulo, campus of São Carlos, through the Professor. Dr. Gilberto Chierice, began research for the development of a new polyurethane polyol derived from the castor (11). Chemical or biological stability, density, and appropriate weight, strength and elasticity, and low cost are essential qualities for the appointment of a biomaterial, but all these factors must be combined with the biocompatibility, which is the primary requirement Proposed Use of the Computer as a Tool to Aid Analysis of Properties of Materials in Fixators of Spine for a material that can enter into contact with living tissue without damaging it (12). 2. MATERIALS AND METHODS METHODS 2. M AT2.EMATERIALS R I ALS A N DAND M ET HODS 2. MATERIALS AND METHODS The modeling of the internal fixators of the spine 121 locked to prevent movement of the whole. Material Modulusofelasticity(GPa) CoefficientPoisson Table 1 Properties of Materials 1,37 Bone1 TableModulus 1 Properties Materials of of0,30 The modeling of the internal fixators of the spine (rods, shoes, Coefficient shoes, screws) andofwill bone structure (cylMaterial elasticity Modulus of 2 The modeling ofnuts, the internal fixators thebe spine (rods, nuts,(rods, screws) and bone structure (cylinder) made up inshoes, Table 1 Properties0,33 of Materials 103,4 Titanium Poisson Coefficient inder) will be made up in modeling software (Figure (GPa) Material elasticity modeling software (Figure 1).structure nuts, screws) and (cylinder) willspine be made in Modulus of The modeling ofbone the internal fixators of the (rods,upshoes, 0,7 0,37 Polyurethane3 Poisson Coefficient 1). (GPa) modeling software (Figure elasticity 1 Material nuts, screws) and bone 1). structure (cylinder) will be made up in Bone 1,37 0,30 Poisson Table1Properties of Materials (GPa) modeling software (Figure 1). Bone1 1,37 0,30 Titanium2 1 103,4 0,33 Bone 1,37 0,30 0,33 Polyurethane 0,7 103,4 0,37loads Table 2 Titanium shows3 2the different values of the to 3 2 Polyurethane 0,7 0,37 be applied in the internal fixation Titanium 103,4of the vertebral 0,33 [13]Literature valuesand Ko, 3C.C. et al. (1992) Polyurethane 0,7 castor) (13, 0,37 column (titanium polyurethane 14, [14]Literature values Clelland al. et (1991) [13]Literature values Ko, et C.C. al. (1992) 15). [14]Literature values Clelland etG.D. al. [12]Literature values Silvestre Filho, [13]Literature values Ko, C.C. et (1991) al.(2004) (1992) values Silvestre Filho, (2004) TESTS[12]Literature LOAD(N) [14]Literature values Clelland et al.G.D. (1991) [12]Literature values Silvestre Filho, G.D. (2004) Figure 1 – Fixators x Bone Structure Structure After modeling the whole,1the geometric data will be transferred Figure – Fixators x Bone Structure Figure1– Fixators Structure Figure 1 –x Bone Fixators x Bone After modeling the whole, the geometric data will be After modeling the whole, the geometric data transferred to the simulation software. The problem willwill be be divided following thesimulation steps for using the Finite Element Method thereby to After the software. The problem will be divided transferred to the simulation software. The problem modeling the whole, the geometric data will be transferred generating meshes for each of the components (nails, shoes, following the steps for using the Finite Element Method will be divided following the steps for using thedivided Fito the simulation software. The problem will bethereby bolts,nite screws sos,meshes bone structure) (Figure 2). generating forforeach ofthe theFinite components shoes, following the Method steps using Element (nails, Method thereby Element thereby generating meshes for bolts, screws sos, bone for structure) (Figure 2). generating meshes each of the components (nails, shoes, each of the components (nails, shoes, bolts, screws, bolts, screws sos,(Figure bone structure) (Figure 2). bone structure) 2). Figure 2 - Mesh Generation Figure 2 - Mesh Generation SILVESTRE FILHO [12], analyzed by means of tensile and Figure 2 - Mesh Generation Figure2–MeshGeneration bending mechanicalFILHO properties castor oilby polymer SILVESTRE [12],ofanalyzed means reinforced of tensile and bending mechanical properties of castor oil polymer by carbon fiber rods in(12), hip analyzed implants. Were also carried out and SILVESTRE FILHO [12], analyzed by means ofreinforced tensile and Silvestre Filho by means of tensile computer simulations of the stem, along with the test device by bending carbon fiber rods in hip implants. Were also carried out mechanical properties of castor oil polymer reinforced bending mechanical properties of castor oil polymer designed comparison with thehip experimental results. Intest their computer simulations of in stem, along with the deviceout byforcarbon fiber rods implants. Were also carried reinforced carbon fiber rods in hip implants. simulations were used as input the elastic designed for by comparison with experimental results. InWere their computer simulations of data thethestem, along modulus with the and test device also carried out computer simulations of the stem, simulations were used as input data the elastic modulus Poisson's ratio of materials used and also the use of the finite designed for comparison with the experimental results. Inand their element method. Poisson's ratiothe of materials anddata alsothe thefor usecomparison ofmodulus the finiteand along with test device designed simulations were used asused input elastic element method. with the experimental their Poisson's ratio of materialsresults. used andInalso the simulations use of the finite Figure 3 - Lateral Flexion tests and flexion-compression Figure3–LateralFlexion tests and flexion-compression Figure 3 - Lateral Flexion tests and flexion-compression 1 981Flexion tests and flexion-compression Figure 3 - Lateral Table 2 shows the different values of the loads to be applied in 2 1177 the internal fixationtheofdifferent the vertebral column (titanium and in Table 2 shows values of the loads to be applied 3 polyurethane 1373 castor). theTable internal fixation of the vertebral column (titanium and in 2 shows the different values of the loads to be applied polyurethane castor). 4 1569of the vertebral column (titanium and the internal fixation Table 2 - 1765 Values for load tests 5 polyurethane castor). Table 2 - Values forLOAD(N) load tests TESTS 6 1961 TESTS LOAD(N) Table 2 Values for load tests 1 981 7 2157 TESTS LOAD(N) 1 981 2 1177 Table2–Valuesfor load tests 981 3 2 1 13731177 1177 4 3 2 15691373 The system of fixation with titanium, 1569 commonly 5 4 3 1765 1373 implemented in patients, using screws 35 mm 1569 long 6 5 4 19611765 and 6 mm in diameter (Figure 4), which is applied 6 5 1765 21571961 at an angle of 760 degrees between the two captive 7 6 2157 1961 Literature [15] screws to thevalues vertebrae, and separate 10mm (16). 2157 Literature values7[15] element method. The were properties theinput materials in internal fixator of thePoisusedof as dataused the elastic modulus and spineson’s and properties bone are materials presented (Table 1). The of the internal fixator of the ratiostructure of materials usedused andinalso the use of the fispine and bone structure presented (Table 1). the fixator Literature [15] USSION The properties of theare materials used in internal of the 3. RESU LTS A Nvalues Dwith DISC nite element method. The properties of materials The system of fixation titanium, commonly implemented Model validation will structure be performed flexion-compression and spine bone (Table The controversy regarding the and methodology for used inand internal fixatorareofpresented the spine and1).bone strucin patients, using screws 35 mm titanium, long 6 mm in diameter The system of fixation with commonly implemented lateralModel bending progressive loading (Figureflexion-compression 3), all degrees of and validation will be performed conducting mechanical tests for the evaluation of ture are presented (Table 1). Model validation will be 4), which is of applied at 35 an angle of 60and degrees in The patients, using screws mm long 6 mmbetween inimplemented diameter freedom lessbending than theprogressive surface the bone(Figure structure lateral 3), (cylinder) all degrees ofand (Figure system fixation with titanium, commonly Model validation will of beloading performed flexion-compression (Figure 4), which is applied at an angle of 60 degrees between the two captive screws to the vertebrae, and separate 10mm orthopedic implants is basically the use of human performed fl exion-compression and lateral bending freedom less than the surface of the bone structure (cylinder) locked to prevent movement of the whole. in patients, using screws 35 mm long and 6 mm in diameter lateral bending progressive loading (Figure 3), all degrees of [16]. the two captive screws to the vertebrae, and separate bones and testing machines (17). To date not known progressive loading (Figure 3), all degrees of freedom locked to prevent movement of the whole. (Figure 4), which is applied at an angle of 60 degrees10mm between freedom less than the surface of the bone structure (cylinder) [16]. the twoimplant captive for screws andexperseparate 10mm ideal usetointhe thevertebrae, spine, and less thantothe surface of the structure (cylinder) stiffness locked prevent movement of bone the whole. [16]. ACTA INFORM MED. 2014 APR 22(2): 120-122 / ORIGINAL PAPER 122 Proposed Use of the Computer as a Tool to Aid Analysis of Properties of Materials in Fixators of Spine geometry of the object can geometry of the object can be modified through software bringing some savings bringing in waste materials. some savings in waste be m mate Figure 5–Points of maximum and minimum stress Figure 5 - Points of maximum and minimum stress Figure 4 - Components of Fixation System [16] 3. RESULTS AND DISCUSSION The controversy regardingof the methodology for conducting Figure 4–Components Fixation System [16] mechanical tests for the evaluation of orthopedic implants is basically the use of human bones and testing machines [17]. could replace the titanium material is expensive. 4. the CONCLUSION Some critical points in geometry of the object can be modified through software bringing some savings From the sum of the results obtained in carrying out the tests in waste materials. concluded that the simulation software proved efficient in Figure 5 - Points of maximum determining the values of compression and tension using the finite element method. The deformations of different materials 4.CONC LUSION were the compared andthe theresults necessary changes for improvements From sum of obtained in carrying couldtests be made on the same without the need of building out the concluded thatmodel the simulation software a new one. 4. CONCLU proved efficient in determining the values of comFrom the sum results obtain pression tension using finiteand element method. Basedand on the literature of thethe subject withofthethe collaboration imental and clinical investigations indicate that in- The ofdeformations of different materials were commedical professionals, the results of that this research serve concluded the will simulation sof creased mechanical stability of thefor system accelerates pared and the for improvements to deliver thenecessary application changes of polyurethane derived from castor To date not known stiffness ideal implant use in the spine, determining the values of compres Figure 4 - Components of Fixation System [16]could oil be in the design internal fixators of the spine. the need bone healing and the rate of pseudarthrosis, made onofthe same model without and experimental anddecrease clinical investigations indicate that method. The deforma increased mechanical of the accelerates and based on thisstability evidence thesystem spinal implantsbone have of building a new one.finite Based element on the literature of the REFERENCES healing decrease (18). the rate of pseudarthrosis, and based on been and developed subject and with the 5. collaboration of medical were compared andprofesthe necessary this evidence the spinalresults implantsare havestill beenfar developed The practical from [18]. ideal sur- sionals, the results of this research will serve to same decould the [1] Keller, T S.; Spengler, D be M ;made Carter, on D R. Geometric, model w gical solution to the problems of the spine, as com- liverelastic, the application of polyurethane derived from and strutural properties maturing rat femora. Journal The practical results are still far from ideal surgical solution to a new of one. 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Utilização da poliuretana da mamona nas formas compacta e pooil in the design ofRev internal fixators o are clear evidences that the poliaxial can 2. rosa and experimental and clinical investigations indicate that [3] Basile, JR R;deBARROS F°, TEP Lesões no preenchimento falha óssea: estudo experimental em da cães.coluna Bras vertebral Ortop. thethere problems related to the alignment of screws screws, and their use 2002; 37(5): 187-194. contribute significantly to address the problems renos esportes. Rev. Bras. Ortop., v. 34, p. 90-96, 1999. the side bars with adjustments, can system further aid accelerates in the increasedwith mechanical stability of the bone 3. Basile JR, Barros R, Tep F. Lesões da coluna vertebral nos esportes. Rev Bras Ortop. lated this to the screws, use with solution typealignment of problem. of It would be and very their difficult at the 1999; 34: 90-96. 4. Bolliger-Neto R, Rossi JDBA,R; Leivas TP, Basile-Junior Pereira CAM, Toledo CS. 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Dissertação – Mestrado – Interunidades em BioengenofCarlos/Faculdade Orthopaedic Research, the problems of the spine, as compared with reconstructive haria de Engenharia São de Medicina deIRibeirão Preto/ v. idea of the use of transverse rods, can perhaps [5] – Escola Ramos, M; deRotbande, I; Shehata, Estudo do 4, p. 57Through the simulation software loads werewhich applied inthe flexionInstituto de Química de São Carlos da Universidade de São Paulo, 2004. comportamento mecânico de sistemas de fixação externa. Rev. compression and lateral flexion to check the mechanical be improved in future or assist in the development of surgery of large joints such as hip and knee, which enable theFilho LA. Compressão axial de corpos vertebrais humanos ensaios com car8. Menezes gas lentas e progressivas, Doutorado – Faculdade de Medicina da Universidade Bras. Ortop., v. 34,Tese n.–8, p. 469-474, 1999. deformations the different alternative systems forstructures. spinal fixation de São Paulo, São Paulo, 1987. [2] Ignácio, H; Mazzer, N Utilização maintenance of ofthe movements takes[16].place even9. spinal Panjabi MM. Biomechanical evaluation of spinal fixation devices: A conceptual frameThrough the simulation software loads were apwork. 1988; 13:TP; 1129-1134. [6] Spine. Leivas, Arenas, EC; Targa, WHC Análise da nas formas compacta e porosa no pre The software for the simulation showed the points of high and arthrodesis andin removing movements in situations plied flexion-compression and lateral flexion to in10. which Brasil AVB, Coelho DG. Um método para medida de movimento em estudos biomecâniestabilidade de três montagens do fixador externo circular. Rev. low voltage (Figure 5) and the critical points occurring in the cos de coluna vertebral. Rev Bras Ortop. 1999; 34: 109-112. estudo experimental em cães. Rev. instruments to that segment ofdeformations the locomotor theMazzer N.v.32, check the of thesystem. differentWithin 11. Bonini Resposta à poliuretana derivada do óleo de mamona: Bras.S,Ortop., n.inflamatória 8, p. 611-614, 1997. geometry of themechanical object.. Estudo da migração e diferenciação de células no sítio inflamatório. Rev Odonto Ciênstructures. 187-194, 2002. scope ofThis theresearch current fixation systems, thereofare clear evidences project aims to contribute to fixators the spine, cia – Fac. Odonto/PUCRS. 2002; 35: 27-37. 12. Silvestre Filho GD. AM Comportamento Mecânicocomputadorizadas do Poliuretano derivado dede óleo fixadores de ma[7] Santos, Simulações for the simulation showed the points madeThe up software derived from castor oil, also show the efficiency of that the computational screws poliaxial can contribute significantly to address mona reforçado por fibra de carbono: contribuição para o projeto de haste de implante internos de coluna utilizando o método dos elementos finitos. methods for simulation of fasteners of high and low voltage (Figure 5) andand theanalyze critical de quadril, Dissertação – Mestrado – Escola de Engenharia de São Carlos da Universi[3]– Basile, JR em R;Bioengenharia BARROS -F°, TEP the problems related to inthe alignment screws, and theirdade use de São Paulo,– 2004. Dissertação Mestrado Interunidades thepoints mechanical behavior of materials and study occurring the geometry ofof thechanges object..in the 13. Ko CC, Chu CS. Effects of posts on dentin stress distribution in pulpless teeth. J ProsEscola de Engenharia de Sãoesportes. Carlos/ Faculdade Medicina de the material savings in time and cost. Dent. 1992; 68: 421-427. nos Rev.deBras. Ortop., v. 34 with thegeometry side bars with adjustments, can further the This of research project aims to contribute to fixatorsaid inthet Ribeirão Preto/ Instituto definite Química deanalysis Sãoin around Carlos 14. Clelland NL, Ismail YH. Three-dimensional element stress the da of the spine, made up derived from castor oil, also screw-vent implant. J Oral Maxillofac Implants. 1991; 6: 391-398. solution The thispolyurethane type of derived problem. It would very difficult atUniversidade theRCBS. Influência de São Paulo, 2004. from castor oil is abe cheap material dos componentes de um sistema de fixação vertebral na estashow the efficiency of computational methods for 15. Lerouge bilidade biomecânica, Dissertação – Mestrado–Interunidades em Bioengenharia–Escoand depending on the analysis structural could replace the [4] Bolliger-Neto, R; Rossi, JDBA. moment, to abandon the use of systems that use the longitudinal la de Engenharia de São Carlos/Faculdade de Medicina de Ribeirão Preto/ Instituto de simulation of is fasteners and analyze mechanical titanium material expensive. Some criticalthe points in the Química de São Carlos da Universidade de São Paulo, 2001. Pereira, CAM; Toledo, CS Estud rods to connect the implants, but many believe it is 16.valid toHLA, Shimano AC. EnsaiosR;mecânicos Defino de um sistema de fixação pedicular com behavior of materials and study changes in thethat geombarra transversal. Acta Ortop Bras. 2001; 9(4): 14-20. montagens dodefixador externo LIM-4 divulge the of the savings use ofin time transverse can etry idea of the material and cost.rods, which 17. Filho GRM, Reis FB. Avaliação biomecânica dos componentes um sistema de fixação intramedular bloqueado para tíbia. Rev Bras Ortop. 2004; 39(8): 433-447. The polyurethane derived from castor oil is a cheap torção. Hosp Med Sã perhaps be improved in future or assist in the development of A, Bergmann G, Graichen 18. Rohlmann F. Loads onRev internal spinal fixatorsClin measuredFac in different body positions. Spine J. 1999; 8: 354-359. material and depending on the analysis structural 3. RESULTS AND DISCUSSION 5. REFEREN alternative systems for spinal fixation [16]. 1998. ORIGINAL PAPER / ACTA INFORM MED. 2014were APR 22(2): 120-122in flexionThrough the simulation software loads applied compression and lateral flexion to check the mechanical [5] Ramos, M; Rotbande, I; comportamento mecânico de sistem