Davi Marco Lyra-Leite - Usc - University of Southern California

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Davi Marco Lyra-Leite - Usc - University of Southern California
Davi Marco Lyra-Leite
Contact
Information
Education
Laboratory for Living Systems Engineering
USC Viterbi School of Engineering
1042 Downey Way
University of Southern California (USC)
Los Angeles, CA 90089
Voice: (213) 821-0832
E-mail: [email protected]
Site: www-scf.usc.edu/∼leite
University of Southern California (USC), Los Angeles, CA, United States of America
Philosophy Doctor in Biomedical Engineering (in progress)
• Advisor: Megan L. McCain, PhD.
• Focus: Cellular and tissue engineering, disease modeling, precision medicine.
Master of Science in Biomedical Engineering (in progress)
• Focus: Cellular and tissue engineering, disease modeling.
Master of Science in Electrical Engineering (in progress)
• Focus: Signal processing and medical imaging.
Health, Technology and Engineering Certificate (in progress)
• Development of innovative technologies for the healthcare industry, analysis of healthcare systems and healthcare economics.
University of Brasilia (UnB), Brasilia, DF Brazil
Bachelors of Science in Electrical Engineering (graduation: July, 2012)
• Advisor: Joao Luiz Azevedo de Carvalho, PhD.
• Area of Study: Digital Image and Signal Processing - focus: Medical Imaging, Magnetic
Resonance Imaging.
Research
Projects
Laboratory for Living Systems Engineering, USC, Los Angeles, CA United States
Extracellular matrix regulation of mitochondria structure and function in engineered cardiac
tissues
MRI
June 2014 to Present
• Project under guidance of Professor Megan McCain, PhD.
• Comparison of the structure and function of mitochondria in engineered cardiac tissues
as a function of extracellular matrix stiffness and tissue alignment.
• Academic collaboration with Cedars-Sinai Metabolism and Mitochondrial Research
Core.
• Research conducted using tissue engineering, micro fabrication, microscopy, image processing, and data analysis.
Modeling diabetic cardiomyopathy in vitro
MRI
October 2015 to Present
• Project under guidance of Professor Megan McCain, PhD.
• Analysis of the functional and metabolic changes in cardiac myocytes due to diabetic
cardiomyopathy.
Optical mapping of whole mouse hearts
MRI
January 2015 to December 2015
• Collaboration project between the Laboratory for Living Systems Engineering and
Henry Sucov’s Laboratory.
• Development with Yukiko Yamaguchi of an optical mapping system of whole mouse
heart to study the effects of the presence of fat in the sinoatrial junction.
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Magnetic Resonance Engineering Laboratory, USC, Los Angeles, CA United States
Image Formation and Image Analysis for MRI Data
MRI
September 2012 to May 2014
• Project under guidance of Professor Krishna Nayak, PhD.
• Investigation of image analysis and image formation strategies focusing on registration,
segmentation and rapid imaging for MR data.
• Development of algorithms for image analysis and image formation using Matlab.
Toshiba Medical Research Institute USA, Inc, Vernon Hils, IL United States
Image Formation for non-contrast enhanced MR Angiography
MRI
May 2013 to August 2013
• Summer internship research project under guidance of Dr. Mitsue Miyazaki and Professor Krishna Nayak, PhD.
• Investigation of image formation algorithms to be used in accelerated non-contrast enhanced MR angiography.
• Development of algorithms for image formation using Matlab.
Medical Imaging and Signal Processing Research Group (GPSIM), UnB, Brasilia,
DF Brazil
Reconstruction of Magnetic Resonance Images of Flow using Parallel Imaging
MRI
June 2010 to November 2012
• Project under guidance of Professor Joao Luiz Carvalho, PhD.
• Investigation of the use of parallel imaging in order to increase the acceleration factor
of data acquisition from cardiovascular magnetic resonance of flow, obtained using the
spiral Fourier Velocity Encoding technique.
• Implementation of an image reconstruction algorithms using the iterative self-consistent
parallel imaging reconstruction — SPIRiT —, 3D SPIRiT, temporal acceleration schemes
and spiral Fourier velocity encoding.
• Investigation of the use of multi-dimensional decomposition schemes to reduce noise
and improve data reconstruction — under supervision of professor Joao Paulo Carvalho
Lustosa da Costa, Dr-Ing.
Department of Computer Science (CIC), UnB, Brasilia, DF Brazil
Indoor vs Outdoor Scene Classification
October to December 2009
• Project under the guidance of Professors Alexandre Zaghetto, Dsc., Bruno Luiggi Espinoza Macchiavello, DSc, and Dibio Leandro Borges, PhD.
• Development of a system to be used to identify the nature of an image, whether it was
taken in an indoor or outdoor environment, working with aspects of Artificial Intelligence
(AI) and Computational Photography.
Digital Image and Video Processing Group, UnB, Brasilia, DF Brazil
Color Calibration Between Monitors and Printers
Aug 2009 to September 2010
• Scientific Initiation Project of the Scientific Initiation Program at the University of
Brasilia (ProIC) under the guidance of Professor Ricardo Lopes de Queiroz, PhD, and
Professors Camilo Chang Dorea, PhD, and Alexandre Zaghetto, DSc.
• Development of a system to be used for color calibration between monitors and printers
using a digital camera.
Teaching
Experience
Department of Biomedical Engineering USC
January 2015 to May 2015
• Teaching assistant in the course BME 410 Introduction to Biomaterials and Tissue Engineering of 51 students.
IEEE Student Branch University of Brasilia (SB IEEE UnB)
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June 2012
• Taught a MATLAB course for undergraduate students and engineering professionals, total
of 28 students.
Department of Electrical Engineering UnB (ENE)
March 2011 to August 2011
• Teaching assistant and grader in the course ENE 169111 Theory of Communications of 20
students.
• Supported students during the course period with coursework assessment, and lecturing
review sessions.
• Aided the teachers in correcting the laboratory assignments and computational projects.
Department of Computer Science, UnB (CIC)
March 2010 to March 2011
• Teaching assistant in the course CIC 117242 Introduction to Digital Image Processing of
15 students over two semesters.
• Supported students during the course period, especially with assignments and final projects.
• Graded the student’s assignments for different course projects.
Dean of Extension, UnB (DEX)
April 2009 to February 2010
• Teaching assistant in the discipline DEX 200212 Construction of Social and Multidisciplinary Projects instructional team of 100 students over two semesters.
• Provided in-class and on-line support to students during the construction of workshops and
classes to be applied during the Rondon Project – a nationwide outreach activity focusing
on aiding deprived communities.
Professional
Experience
Toshiba Medical Research Institute USA, Inc., Vernon Hills, IL, USA
Clinical Research Intern
May to August 2013
• Clinical research intern in MRI, working under supervision of Dr. Mitsue Miyazaki.
Podion Preparatory Course and Instituto Tecnologico de Aprovacao, Brasilia, DF
Brazil
Tutor
April 2008 to Oct 2010, and Feb to August 2012
• Physics, Chemistry and Mathematics tutor in the High School and pre-admission test
levels.
Teacher
September 2009 to Oct 2010, and Apr to August 2012
• Taught review and advanced level lectures on Physics and Chemistry to students in
high school and pre-admission test levels, lecturing to more than 200 students over one
year and a half.
Extension and
Outreach
Activities
Mercado Popular
Columnist and Editor
January 2015 to present
• Writes articles related to public policy, science, education and healthcare.
• Edits the articles on public policy and economic welfare.
IEEE Student Branch University of Brasilia (SB IEEE UnB)
Events Committee
April 2011 to July 2012
• Organized seminars and courses promoted by the Student Branch of IEEE at the University of Brasilia.
• Elaborated documents to be used by the SB in projects and proposals submitted to the
University and to the IEEE.
Dean of Extension, University of Brasilia (DEX)
Projeto Rondon
September 2008 to February 2010
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• Visited three cities: Palmital de Minas and Cabeceira Grande, in Minas Gerais; and
Itaruma, in Goias, in order do conduct workshops and seminars.
• Workshops and seminars focused on: general topics of health (personal care, sexual
education, diabetes and hypertension); entrepreneurship (how to organize cooperatives
and associations); and techniques of recycling.
• Worked alongside students from different majors and universities in order to improve
life standard and to change social paradigms of the visited communities.
Alianca Pela Liberbedade - Student Association
Founding Member and Advisor
May 2009 to present
• Worked with students from different areas in the University of Brasilia student movement.
• Helped organizing seminars, guest lectures, workshops, and campaigns for Undergraduate Student Government (DCE) and students’ representation in the University’s superior
councils (CEPE, CAD, Consuni).
• Writes articles for the group’s website focusing on education and scientific research.
Journal Papers
LYRA-LEITE DM, da COSTA JPCL, CARVALHO JLA. Improved MRI reconstruction and
denoising using singular values decomposition approximation. Revista Ingenieria, Vol 17, No
2, Bogota, Colombia, 2012.
International
Conferences
LYRA-LEITE DM, NAYAK KS, CARVALHO JLA. Acceleration of spiral Fourier velocity
encoded MRI using 3D SPIRiT. Abstract 1352, presented at the 21st ISMRM Annual Meeting
& Exhibition and published in the conference proceedings, 2013.
LYRA-LEITE DM, CARVALHO JLA. Parallel imaging acceleration of spiral Fourier velocity encoded MRI using SPIRiT. Presented at the 34th Annual International Conference of the
IEEE Engineering in Medicine & Biology Society and published in the conference proceedings,
2012.
LYRA-LEITE DM, CARVALHO JLA. Accelerated spiral Fourier velocity encoded MRI using SPIRiT parallel imaging. Abstract 1820, presented at the 20th ISMRM Annual Meeting &
Exhibition and published in the conference proceedings, 2012.
LYRA-LEITE DM, da COSTA JPCL, CARVALHO JLA. Improved MRI reconstruction and
denoising using SVD-based low-rank approximation. Presented at the 2012 IEEE Workshop
on Engineering Applications and published in the conference proceedings, 2012.
MARINS AA, LYRA-LEITE DM, da COSTA JPCL. Simulations of a Dynamical System
Model for Electronic Circuits. Presented at the 2012 IEEE Workshop on Engineering Applications and published in the conference proceedings, 2012.
American
Conferences
ARIYASINGHE NR, PETERSEN AP, RECK C, HSU J, LYRA-LEITE DM, MCCAIN
ML. Extracellular Matrix Regulation of the Structure and Contractility of Engineered Cardiac
Tissues. Proceedings 25th Annual Meeting, Biomedical Engineering Society, 2015.
CHO N, HSU J, LYRA-LEITE DM, MCCAIN ML. Regulation of Cardiac Fibroblast Proliferation by Extracellular Matrix Elasticity. Proceedings 25th Annual Meeting, Biomedical
Engineering Society, 2015.
Brazilian
Conferences
LYRA-LEITE DM, CARVALHO JLA. Reconstrucao de Imagens de Ressonancia Magnetica
de Fluxo com Imageamento Paralelo II (Reconstruction of Magnetic Resonance Images of Flow
with Parallel Imaging II). Presented at the 9th Distrito Federal’s Scientific Initiation Congress,
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2012. (in Portuguese)
LYRA-LEITE DM, CARVALHO JLA. Aceleracao por imageamento paralelo de um exame
de ressonancia magnetica de fluxo cardiovascular. Presented at the XIII Brazilian Congress of
Biomedical Engineering, 2012. (in Portuguese)
LYRA-LEITE DM, da COSTA JPCL, CARVALHO JLA. Reconstrucao melhorada de dados
de ressonancia magnetica usando aproximacao de ordem baixa baseada em decomposicao por
valores singulares. Presented at the XIII Brazilian Congress of Biomedical Engineering, 2012.
(in Portuguese)
LYRA-LEITE DM, CARVALHO JLA. Reconstrucao de Imagens de Ressonancia Magnetica
de Fluxo com Imageamento Paralelo (Reconstruction of Magnetic Resonance Images of Flow
with Parallel Imaging). Presented at 8th Distrito Federal’s Scientific Initiation Congress, 2011.
(in Portuguese)
LEITE DML, de QUEIROZ RL. Calibracao de Cores entre Monitores e Impressoras (Colour
Calibration amongst Monitors and Printers). Presented at 7th Distrito Federal’s Scientific Initiation Congress, 2010. (in Portuguese)
LEITE DML, FARIA DO, de QUEIROZ RL, ZAGHETTO A, DOREA CC. Calibracao de
Dispositivos a Cores usando uma Camera Digital (Calibration of Color Devices using a Digital
Camera). Presented at the Workshop of the Post-Graduation in Computer Science from the
Department of Computer Science at UnB and published in the conference proceedings, 2009.
(in Portuguese)
Other
Publications
LYRA-LEITE DM, CHO N, ARIYASINGHE NR, HSU J, STRICKLAND J, MCCAIN
ML. Regulation of Mitochondrial Function by Tissue Architecture and Matrix Elasticity in
Engineered Cardiac Tissues. Presented at the 20th Fred S. Grodins Biomedical Engineering
Graduate Research Symposium and at the 2016 USC Stem Cell and Developmental Biology
Retreat, 2016.
PETERSEN AP, LYRA-LEITE DM, ARIYASINGHE NR, CHO N, KIM JY, STRICKLAND J, MCCAIN ML. Matrix Elasticity Regulates Conduction Velocity in Engineered Cardiac
Tissues. Presented at the 20th Fred S. Grodins Biomedical Engineering Graduate Research
Symposium and at the 2016 USC Stem Cell and Developmental Biology Retreat, 2016.
ARIYASINGHE NR, RECK CH, PETERSEN AP, LYRA-LEITE DM, HSU J, MCCAIN
ML. Extracellular Matrix Regulation of the Structure and Contractility of Engineered Cardiac
Tissues. Presented at the 20th Fred S. Grodins Biomedical Engineering Graduate Research
Symposium and at the 2016 USC Stem Cell and Developmental Biology Retreat, 2016.
LYRA-LEITE DM, ARIYASINGHE NR, HSU J, STRICKLAND J, MCCAIN ML. Extracellular matrix regulation of mitochondrial membrane potential in engineered cardiac tissues.
Presented at the USC-UCLA-UCSF Tri-Institutional Stem Cell Retreat, 2015.
CHO N, HSU J, LYRA-LEITE DM, MCCAIN ML. Regulation of Cardiac Fibroblast Proliferation by Extracellular Matrix Elasticity. Presented at the USC-UCLA-UCSF Tri-Institutional
Stem Cell Retreat, 2015.
ARIYASINGHE NR, HSU J, PETERSEN AP, RECK C, LYRA-LEITE DM, MCCAIN ML.
Extracellular Matrix Regulation of Engineered Cardiac Tissue Contractility. Presented at the
USC-UCLA-UCSF Tri-Institutional Stem Cell Retreat, 2015.
CHO N, HSU J, LYRA-LEITE DM, MCCAIN ML. Regulation of Cardiac Fibroblast Prolif-
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eration by Extracellular Matrix Elasticity. Presented at the 19th Fred S. Grodins Biomedical
Engineering Graduate Research Symposium, 2015.
ARIYASINGHE NR, HSU J, PETERSEN AP, RECK C, LYRA-LEITE DM, MCCAIN ML.
The Combined Effects of Matrix Composition and Elasticity on the Structure and Function of
Cardiomyocytes. Presented at the 19th Fred S. Grodins Biomedical Engineering Graduate Research Symposium, 2015.
LYRA-LEITE DM. Reconstrucao de Imagens de Ressonancia Magnetica com Imageamento
Paralelo (Reconstruction of Magnetic Resonance Images with Parallel Imaging). IEEE R9 Student Paper Contest. Brasilia, DF Brazil, 2011. (in Portuguese) (Awarded the 2nd Best Paper
in Electrical Engineering)
Awards and
Honors
USC Graduate School
• Annenberg PhD Fellowship, 2012-16.
Dean of Education and Undergraduate Studies (DEG) of UnB
• Travel Grant (ISMRM Annual Meeting and Exhibition), 2012.
International Society for Magnetic Resonance in Medicine
• Educational Stipend, 2012, 2013.
Institute of Electrical and Electronics Engineers Region 9
• 2nd Position, IEEE R9 Student Paper Contest (Electrical Engineering), 2011.
Dean of Research and Graduate Studies (DPP) of UnB
• Scientific Initiation Fellowship (Color Constancy and Calibration of Optical Devices), 2009.
• Scientific Initiation Fellowship (Reconstruction of Magnetic Resonance Images of Flow Using Parallel Imaging), 2010.
• Scientific Initiation Fellowship (Reconstruction of Magnetic Resonance Images of Flow Using Parallel Imaging II), 2011.
Conferences
and Workshops
2016 USC Stem Cell and Developmental Biology Retreat
Galen Center, Los Angeles, CA United States
San Diego
May 24th , 2016
20th Fred S. Grodins Biomedical Engineering Graduate Research Symposium
University of Southern California, Los Angeles, CA United States
San Diego
April 1st , 2016
USC-UCLA-UCSF Tri-Institutional Stem Cell Retreat
The Fess Parker, Santa Barbara, CA United States
San Diego
May 17 to 19th , 2015
4th Annual Ming Hsieh Department of Electrical Engineering Research Festival
University of Southern California, Los Angeles, CA United States
San Diego
October 11th , 2013
ISMRM 21st Annual Meeting and Exhibition
Salt Place Convention Center, Salt Lake City, Utah United States
Melbourne
April 20 to 26th , 2013
3rd Annual Ming Hsieh Department of Electrical Engineering Research Festival
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University of Southern California, Los Angeles, CA United States
San Diego
February 6th , 2013
34th Annual International Conference of the IEEE Engineering in Medicine &
Biology Society
Hilton San Diego Bayfront, San Diego, CA United States
San Diego
August 28 to September 1st , 2012
ISMRM 20th Annual Meeting and Exhibition
Melbourne Convention and Exposition Centre, Melbourne, VIC Australia
Melbourne
May 5 to 11th , 2012
10th Week of the Department of Electrical Engineering
October 3 to 7th , 2011
University of Brasilia, Brasilia, DF Brazil
• Member of organizing committee;
• Coordinator of the event’s press committee and social media (Facebook page and Twitter account);
• Editor and writer of the event’s official blog, which published reviews about the conferences and lectures that occurred during the Week.
8th Distrito Federal’s Scientific Initiation Congress
September 12 to 15th , 2011
University of Brasilia, Brasilia, DF Brazil
3rd National Forum on Innovation in Healthcare in Brazil
April 7th , 2011
Brazilian Institute of for Responsible Action, Brasilia, DF Brazil
1st Distrito Federal’s Seminar on Health Technologies Assessment
Health Technologies Assessment Nucleus, Distrito Federal’s Bases Hospital, Brasilia, DF
Brazil
February 28th , 2011
7th Distrito Federal’s Scientific Initiation Congress
University of Brasilia, Brasilia, DF Brazil
November 8 to 11th , 2010
Brazilian Symposium on Electrical Systems
Brazilian Automatic Society, Belem, PA Brazil
Related
Education
May 18 to 21th , 2010
Coursera, On-line Education
Stanford University
October 10th to December 19th , 2011
Machine Learning
Duke University
January 14th to March 18th , 2013
Image and Video Processing
University of Brasilia, Brasilia, DF Brazil
Electroencephalography with Tensors
Programming Course C/C++
Neural Networks and Fuzzy Logic
MATLAB Course – ENETEC
7 of 8
October 3 to 7th , 2011
February 22nd to March 5th , 2010
October 5 to 9th , 2009
October 7 to 28th , 2008
Professional
Societies
Student
Student
Student
Student
Student
Member,
Member,
Member,
Member,
Member,
American Heart Association
Biomedical Engineering Society (BMES)
the Institute Electrical and Electronics Engineers (IEEE)
IEEE Signal Processing Society
IEEE Engineering in Medicine and Biology Society
Languages
Portuguese (Native Language)
English (Fluent - Second Language)
Holds a Test of English as Foreign Language (TOEFL) internet based test (iBT) score of
108. Exam taken in September 2011.
Spanish (Advanced)
Fluent reading, excellent writing, listening and good speaking levels.
French (Advanced)
Finished the advanced level course at UnB Idiomas — University of Brasilia Language
School — in July 2012.
Catalan (Basics)
Good reading comprehension.
Technical Skills Matlab experience: image and signal processing, neural networks, Fourier transforms.
Matlab toolboxes: image processing, neural networks, signal processing, svmdecision, image
formation, image registration, SPIRiT, nuFFT.
Programming: C, C++, Pascal, VHDL, VRML, Matlab
Applications: TEX, LATEX, Autocad, ImageJ, CosmoWorlds, Hiperion, Multisim, Microsoft
Office, and other common productivity packages for Windows.
Operating Systems: Microsoft Windows, Mac OSX, Ubuntu, iOS and Android
Microscopy: Nikon wide-field and confocal.
Micro fabrication: photolitography, microcontact printing.
Tissue culture: maintenance of mammalian differentiated cells and cell lines, cell isolation from
tissue samples.
Last Update: May 27, 2016
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