Plenary sessions - Faculdade de Medicina da USP
Transcrição
Plenary sessions - Faculdade de Medicina da USP
SPSAS- Advances in Molecular Oncology: Translating Molecular Biology into Cancer Treatment Day 02/02/2013 Time 14:00 – 17:30 Check in, credentials, material distribution 07:30 – 08:45 Check in, credentials, material distribution 09:00 – 09:20 Opening Ceremony and Welcoming Remarks Prof Dr José Otávio Auler Prof Dr Giovanni Guido Cerri Prof Dr Marco Antônio Zago Prof Dr José Eluf Neto Prof Dr Roger Chammas Prof Dra Maria A Nagai Plenary sessions FMUSP Prof Dr Flavio Fava de Moraes Prof Dr Carlos Henrique de Brito Cruz Prof Dr Paulo Hoff 03/02/2013 Scientific Program 09:30 – 09:40 09:40 – 10:20 10:20 – 10:50 10:50 – 11:20 11:20 – 12:20 12:20 – 14:00 Director in Office of Medical School, University of São Paulo (FMUSP) Director of Medical School, University of São Paulo (FMUSP) Secretary of Health of the State of São Paulo Pro-Chancellor of Research of the University of São Paulo (USP) Executive Director of the Laboratories of Medical Investigation (LIMs) Director of Medical School Foundation (FFM) Scientific Director of Foundation for Research Support of São Paulo (FAPESP) Head of Clinical Oncology- Medical School, University of São Paulo and ICESP Clinical Diretor Head of Basic Oncology- Medical School, University of São Paulo (FMUSP) Associate Professor, Medical School, University of São Paulo (FMUSP) Paulo Hoff – Welcome Head of Clinical Oncology- Medical School, University of São Paulo and ICESP Clinical Diretor, São Paulo, Brazil Carlos Henrique de Brito Cruz Diretor científico FAPESP, São Paulo, Brazil Marco Antônio Zago – to be defined Pro-Chancellor of Research of the University of São Paulo (USP), São Paulo, Brazil Coffee break Opening conference Molecular Imaging and the tumor microenvironment Robert Gillies, Moffitt Cancer Center, Tampa, USA Brunch Chairs persons: José Eluf Neto 14:00 – 15:00 15:00 – 16:00 Epidemiology in the "omics" era: will the leaves hide the forest? Núria Malats, CNIO, Madrid, Spain Molecular Pathology in Breast Cancer as an example of translational cancer research Fernando Schmitt, IPATMUP, Porto, Portugal 16:00 – 16:30 Coffee break 16:30 – 17:30 Hepatocellular carcinoma – advances in the integration of morphological and molecular aspects, towards a new classification useful for clinical decisions Park YN, Yonsei University College of Medicine, Seoul, Korea 17:30 – 18:30 Role of biomarkers in cancer detection and patient management Michael J Duffy, School of Medicine & Medical Science, St Vincents University Hospital, Dublin, Ireland Welcome Cocktail 19:00 – 21:00 SPSAS- Advances in Molecular Oncology: Translating Molecular Biology into Cancer Treatment Day Time Room A MC1 - Immunology for the non-immunologist José Alexandre Barbuto, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil MC2 - Principles of Clinical Research in Oncology Room B Rachel Simoes Pimenta Riechelmann, ICESP, São Paulo, Brazil MC3 - 3D culture and mammary gland tumour engraftment as models Room C for studying the biology and therapeutics Bruce Elliott, Queen’s University, Canada Room A Chair persons: M Mitzi Brentani and Maria A Nagai Session 1: Breast cancer Mini-courses 8:00 – 8:45 09:00 – 09:50 Introduction to mammary gland biology and breast cancer Paraic Kenny,Albert Einstein College of Medicine, Bronx, NY,USA 09:50 – 10:30 A novel Src/ezrin pathway in breast cancer metastasis: a potential predictive marker Bruce Elliott, Queen’s University, Kingston, Canada 10:30 – 11:00 Coffee break 11:00 – 11:30 Transcriptional profile as prognostic and predictive factor in breast cancer Maria A K Folgueira, Medical School, University of São Paulo, São Paulo, Brazil Initiation and Progression of breast cancer: Insights from gene expression analysis Dirce M Carraro, A C Camargo Hospital, São Paulo, Brazil 11:30 – 12:00 12:00 – 12:30 The role of tumor markers for diagnosis, prognosis and evaluation of therapy response in breast cancer Vivian Barak, Associate Professor in Oncology, Hebrew University, Jerusalem, Israel Room B Chairs persons: Luisa L Villa and Anna R. Giuliano 09:00 – 09:50 Epidemiology of anogenital cancers. Anna R. Giuliano, H. Lee Moffitt Cancer & Center Research Institute, Tampa, USA Session 2: Anogenital tumors 09:00 – 12:30 Concurrent session - Molecular biology of cancer: an update ICESP 04/02/2013 Scientific Program 09:50 – 10:30 Carcinogenic role of HPV in anogenital tumors Enrique Boccardo, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil 10:30 – 11:00 Coffee break 11:00 – 11:30 Immune responses to HPV in normal tisssue and tumors of the uterine cervix. Ligia A. Pinto, National cancer Institute, Maryland, USA HPV vaccination for anogenital cancer prevention Luisa Lina Villa, Medical School, University of São Paulo, São Paulo, Brazil-ICESP 11:30 – 12:00 12:00 – 12:30 Anogenital Cancer Treatment Edmund Chada Baracat, Medical School, University of São Paulo, São Paulo, Brazil 12:30 – 14:00 Brunch and Poster Session SPSAS- Advances in Molecular Oncology: Translating Molecular Biology into Cancer Treatment Day Scientific Program Time Session 3: Gastric cancer Session 4: Hepatocellular and pancreatic tumors Concurrent session - Molecular biology of cancer: an update 04/02/2013 ICESP 14:00 – 17:30 Room A Chairs persons: Ulysses Ribeiro, Jr and Ivan Cecconello 14:00 – 14:50 Molecular and immunohistochemical markers of gastric carcinoma differentiation and progression. Maria de Fátima Machado Henriques Carneiro – IPATIMUP, Porto, Portugal 14:50 – 15:30 15:30 – 16:00 Familial gastric cancer: overview and guidelines for management. Osmar K. Yagi – Clinics Hospital-Medical School, University of São Paulo, São Paulo, Brazil Gastric stump carcinoma. An experimental model for gastric carcinogenesis? Adriana Vaz Safatle Ribeiro – Clinical Hospital-Medical School, University of São Paulo and ICESP, São Paulo, Brazil 16:00 – 16:30 Coffee break 16:30 – 17:00 Targeted therapy in gastric cancer. Renata de Almeida Coudry – Cancer Institute São of Paulo State ICESP Room B Chairs persons: Venancio Alves and Young N Park 14:00 – 14:50 Morphological and Molecular characterization of the vascular features of hepatocellular carcinoma from Dysplasia to Advanced Neoplasia Annette Gouw, University Medical Center Groningen, Groningen, Netherlands 14:50 – 15:30 Hypoxia and Hepatocarcinogenesis, emphasizing the putative role of monocarboxylate transporters Venancio Alves, Medical School, University of São Paulo/ICESP, São Paulo, Brazil A fibrous stromal component in hepatocellular carcinoma reveals a cholangiocarcinoma-like gene expression trait and EMT. Young N Park, Yonsei University College of Medicine Seodaemun, Seoul, Korea. 15:30 – 16:00 16:00 – 16:30 Coffee break 16:30 – 17:00 Cholangiocarcinoma and variants Evandro S Mello, Medical School, University of São Paulo, São Paulo, Brazil Room A 17:00 -17:30 Room B The PrimerBank database of human and mouse primer pairs for gene expression, detection and quantification Athanasia Spandidos - Medical School, University of Athens, Greece and Harvard Medical School, Boston, USA To be defined 17:00 -17:30 Conference 17:30 – 18:30 Chair person: Maria A Nagai Ras oncogene and human cancer Demetrios Spandidos, Medical School, University of Crete, Creta, Greece SPSAS- Advances in Molecular Oncology: Translating Molecular Biology into Cancer Treatment 8:00 – 8:45 Time Room A Room B MC1 - Immunology for the non-immunologist José Alexandre Barbuto, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil MC2 - Principles of Clinical Research in Oncology Rachel Simoes Pimenta Riechelmann, ICESP, São Paulo, Brazil MC3 - 3D culture and mammary gland tumour engraftment as models for studying the biology and therapeutics Bruce Elliott, Queen’s University, Canada Room A Chairs persons: Gilberto de Castro and …. Session 5: Head and Neck tumors Room C 09:00 – 09:50 Predictive biomarkers analysis using FISH in lung cancer MarileilaVarella-Garcia, School of Medicine, Division of Medical Oncology, University of Colorado Denver, Denver, USA 09:50 – 10:30 miRNAs as gene regulators in thyroid cancer Edna Teruko Kimura Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil 10:30 – 11:00 Coffee break 11:00 – 11:30 Epigenetic silencing: its role in upper aerodigestive tract carcinogenesis André Lopes Carvalho, Cancer Hospital of Barretos, Barretos, Brazil Molecular epidemiology of lung câncer Carlos Gil Ferreira, National Institute of Cancer, Rio de Janeiro, Brazil Cancer-stromal interactions in upper aerodigestive cancers Eloiza Helena Tajara da Silva, State of São Paulo University, São José do Rio Preto, Brazil 11:30 – 12:00 12:00 – 12:30 Room B Chairs persons: Eduardo Rego and Robert Gallagher Session 6: Hematopoietic tumors Concurrent session - Molecular biology of cancer: an update 09:00 – 12:30 05/02/2013 ICESP Mini-courses Day Scientific Program 09:00 – 09:50 ATRA-resistance in acute promyelocytic leukemia cells and its functional correlations. Robert Gallagher, Montefiore Medical Center, Albert Einstein Cancer Center, USA 09:50 – 10:30 Mitochondrias as targets for acute leukemia treatment Eduardo Rego, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil 10:30 – 11:00 Coffee break 11:00 – 11:30 Telomere length regulation in hematological malignancies Rodrigo Calado, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil Investigation of new targets in bone marrow cancers Sara T. O. Saad, University of Campinas, Campinas, Brazil Title to be defined Gisele Colleoni , Federal University of São Paulo, São Paulo, Brazil 11:30 – 12:00 12:00 – 12:30 12:30 – 14:00 Brunch and Poster Session SPSAS- Advances in Molecular Oncology: Translating Molecular Biology into Cancer Treatment Day Scientific Program Time Session 7: Prostate cancer 14:00 – 14:50 Molecular basis of targeted therapy in metastatic renal cancer Marc Garnick, Harvard Medical School, Boston, USA 14:50 – 15:30 Epigenetics in prostate cancer: biologic and clinical relevance. Katia Moreira Leite, Medical School, University of São Paulo, São Paulo, Brazil 15:30 – 16:00 Translational research in bladder cancer: from molecular pathogenesis to useful tissue biomarkers. Alberto Azoubel Antunes, Medical School, University of São Paulo, São Paulo, Brazil 16:00 – 16:30 Coffee break 16:30 – 17:00 Tumor banks: the cornerstone of basic research in urology. Sabrina Reis, Medical School, University of São Paulo, São Paulo, Brazil 17:00 – 17:30 Molecular alterations and drug development for metastatic castrationresistant prostate cancer. Marc Garnick, Harvard Medical School, Boston, USA Room B Chairs persons: Suely K Marie and Gregory Riggins Session 8: Central nervous system tumors Concurrent session - - Molecular biology of cancer: an update 05/02/2013 ICESP 09:00 – 12:30 Room A Chairs persons: Miguel Srougi and Katia Moreira Leite Conference 14:00 – 14:50 Translational cellular and animal models for glioblastoma therapeutic management Gregory Riggins, Ludwig Collaborative, Baltimore, USA 14:50 – 15:30 New and old approaches to search for anti-tumor targets of clinical relevance Mari Cleide Sogayar, NUCEL-Cell and Molecular Therapy Center, University of São Paulo, São Paulo, Brazil Immune panel access as a protection for the central nervous system Regina Pekelmann Markus, Institute of Bioscience, University of São Paulo, São Paulo, Brazil 15:30 – 16:00 16:00 – 16:30 Coffee break 16:30 – 17:00 The proteomic approach to search for new therapeutic targets Jose Cesar Rosa, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil 17:00 – 17:30 Stem cell markers of medulloblastoma as therapeutic targets Carlos Gilberto Carlotti, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil 17:30 – 18:30 Chair person- Roger Chammas New mouse models for in vivo imaging of tumor metastasis: application to gene discovery and drug response in melanoma María S Soengas, Centro Nacional de Investigaciones Oncológicas, Madrid, Spain SPSAS- Advances in Molecular Oncology: Translating Molecular Biology into Cancer Treatment 8:00 – 8:45 Time Room A Mini-courses Day Room B Room C 09:00 – 9:50 9:00 – 12:30 Plenary session MC1 - Immunology for the non-immunologist José Alexandre Barbuto, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil MC2 - Principles of Clinical Research in Oncology Rachel Simoes Pimenta Riechelmann, ICESP, São Paulo, Brazil MC3 - 3D culture and mammary gland tumour engraftment as models for studying the biology and therapeutics Bruce Elliott, Queen’s University, Canada Chairs persons: Paulo H Saldiva and ..... Environment and cancer Paulo H Saldiva, Medical School, University of São Paulo, São Paulo, Brazil Apoptosis: Extracellular Effects of the Tumor Suppressor Par-4 Vivek Rangnekar, Department of Radiation Medicine, University of Kentucky, Lexington, USA 10:30 – 11:10 Novel Therapeutic Strategies for Recurrent Prostate Cancer Anna Ferrari, NYU Cancer Institute, New York, USA 11:10 – 11:30 Coffee break 11:30 – 12:10 Abnormal O-glycosylation in cancer: from biology to clinical applications Eduardo Osinaga, Faculdad de Medicina, Universidad de la Republica, Montevideo, Uruguay 12:10 – 12:50 Molecular pathways leading to pancreatic cancer Francisco X. Real , CNIO, Madrid, Spain 12:50 – 14:00 Brunch 14:00 – 14:15 Oral presentation – selected papers 14:00 – 17:00 06/02/2013 ICESP 9:50 – 10:30 Conference Scientific Program 14:15 – 14:30 14:30 – 14:45 14:45 - 15:00 15:00 – 15;15 15:15 – 15:45 Coffee break 15:45 – 16:00 16:00 – 16:15 16:15 – 16:30 16:30 - 16:45 16:45 – 17:00 17:00 – 18:00 Chair person: Roger Chammas Tumor heterogeneity Francisco X. Real , CNIO, Madrid, Spain SPSAS- Advances in Molecular Oncology: Translating Molecular Biology into Cancer Treatment Day Scientific Program Time Inherited tumors: Plenary sessions FMUSP 8:00 – 12:30 Chair persons: Lois M Mulligan and Sergio A Toledo 08:00 – 09:00 DICER1 mutations result in a surprising array of phenotypes William D Foulkes, McGill University, Montreal, Canada 09:00 – 9:40 Ovarian cancer susceptibility genes Patricia Tonin, McGill University, Montreal, Canada 9:40 – 10:20 Coffee break 10:20 – 10:40 Mechanisms of RET Receptor Dysfunction Lois M Mulligan, Queen’s University, Kingston, Canada 10:40 – 11:20 Title to be defined Sergio A Toledo, Medical School, University of São Paulo, São Paulo, Brazil 11:20 – 12:00 Title to be defined Patricia Dahia, San Antonio Cancer Institute, San Antônio, Texas, USA 12:00 – 14:00 Brunch Advanced Technologies and cancer therapy 14:00 – 18:30 Plenary sessions1 07/02/2013 Chair persons: Roger Chammas and Francisco Real 14:00 – 15:00 Advances in Nanomedicine and Nanotoxicology: Manipulation of Nanomaterials for Diagnostic and Therapy Valtencir Zucolotto Institute of Phisic, University of São Paulo, São Carlos, Brazil 15:00 – 16:00 Targeted nanoparticles for non-invasive hyperthermia in malignant disease Steven A Curley, MD Anderson Cancer Center in Houston, Texas, USA 16:00 – 16:30 Coffee break 16:30 – 17:30 Identification of subtype-specific breast cancer targets using 3D culture models Paraic Kenny, Albert Einstein College of Medicine, New York,USA 17:30 – 18:30 Reverse engineering multiple myeloma: putting numbers to faces Ariosto Silva, Moffitt Cancer Center, Tampa, FL, USA SPSAS- Advances in Molecular Oncology: Translating Molecular Biology into Cancer Treatment Day Scientific Program Time Chair persons: Roger Chammas and Maria A Nagai Plenary sessions FMUSP 08:00 – 13:00 08:00 – 09:00 Standards for biomarkers and the role of the NCI on global cancer research Jorge Gomez, National Cancer Institute, Bethesda, USA 09:00 – 10:00 The EGFR/HER2 system as therapeutic targets for cancer treatment Michael J Duffy, School of Medicine & Medical Science, St Vincents University Hospital, Dublin, Ireland 10:00 – 10:30 Coffee break 10:30 – 11:20 Biomarkers for prediction of Metastasis in Melanoma Vivian Barak, Associate Professor in Oncology, Hebrew University, Jerusalem, Israel 11:20 – 12:00 Publishing in Biomedical Sciences". 08/02/2013 Demetrios Spandidos, Medical School, University of Crete, Creta, Greece 12:00 – 13:00 Closing Remarks (Roger Chammas; Jorge Gomez; Vivek Rangnekar; Michael J Duffy) and Departure Cancer Institute of São Paulo State Supervised visit: 14:30 – 17:30 Medical School of the University of São Paulo Center of Nuclear Medicine