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Babylon Anti-Aging The first 4000 Years Mankind´s oldest literary Document: The Gilgamesh Epos When the Gods created man, they attributed him mortality as part of his destiny. Eternal life they kept for themselves. B. Kleine-Gunk, Fürth Mesopotamia Ca. 2600 B. C. PreAge PreAge Ancient Egypt The Papyrus Ebers and the Aging Male Syndrome Babylon Gilgamesh and Enkidu Fighting against the Gods in the quest for immortality. How to turn an old (man) into a young one Ca. 1500 B. C. PreAge Ancient Egypt Early Specialisation PreAge Ancient Egypt Learning from the Bees … Propolis Gelée Royale Nr Phit Guardian of the Anal Orifice Frequent enema as common antiaging treatment PreAge PreAge 1 Ancient Egypt Imhotep Ancient Egypt Cleopatra Architect Writer Physician Female Pharao Beauty Icone Author of a Textbook on Cosmetics The first known by name universal genius in the history of mankind 69 B. C. - 30. B. C. Ca. 2700 B. C. PreAge The Bible King David and the Aging Male Syndrome PreAge Ancient Greece The Tithonos Trauma When King David was old and well advanced in years, he could not keep warm even when they put covers over him. So his servants said to him, „Let us look for a young virgin to attend the king and take care of him. She can lie beside him so that our lord the king may keep warm“. Then they searched throughout Israel for a beautiful girl and found Abishag, a Shunammite, and brought her to the king. The girl was very beautiful… (I, Kings1-3) PreAge Ancient Greece Hippocrates: The first Universal Theory of Aging Humoral Pathology (Doctrine of the four essential liquids) Aging as a process of continuous dehydration and loss of internal warmth An example of immortality turning dreadfully wrong PreAge Ancient Greece Hippocrates: Father of Medical Cosmetics Treaty on Female Medicine Collection of prescriptions „to smoothe wrinkles“ „to give the face a nicer appearance“ Ca. 460-377 B. Chr. PreAge PreAge 2 Ancient Rome Cicero: A lawyer in defense of Aging Ancient Rome Galenos of Pergamon Founder of „Galenics“ The first blockbuster in medical cosmetics Unguentum refrigerans („Cold Cream“) Ca. 129-199 A C 106 BC. - 43 BC. PreAge Ancient Rome Sanitas per Aquam PreAge Ancient China Taoism The first Anti-Aging Religion The Invention of Wellness Lao Tse, Ca. 500 BC. PreAge Ancient China Taoism The first Anti-ging Religion - The right Breathing - The right Eating - The right Exercise - The right Sexual Techniques - The right State of Mind PreAge PreAge Ancient China Taoist Sexual Techniques Coitus reservatus as an important Anti-Aging Method „Those who succeed to perform this coitus several times during one single day or night without loosing their essence will be healed of all illness and will prolong their life. By doing so with different women the advantage will be even bigger. If you manage to change your partner more than ten times during the night - this is very excellent.“ PreAge 3 Ancient China´s first Emperor A Victim of Anti-Aging Medicine The Middle Ages Alchemism The Quest for the Secret of Gold and Eternal Life Qin Shi Huang Di 259 - 210 BC. PreAge PreAge The Middle Ages Humoral Pathology The Middle Ages Roger Bacon Restauration of Youth by Inhaling the Breath of Virgins 1214-1292 PreAge Early Renaissance Paracelsus: From Alchemia to Pharmacia The Middle Ages Alchemism: The Elixir of Life - PreAge The Quinta Essencia: High-proof alcohol Liquid like water, yet inflamable Cooling to the skin, yet warming to mouth and stomach A solvent for mineral substances, yet a preservative for organic material Opus magnum „De vita longa“, 1526 Philipus Theophrastus Bombastus von Hohenheim, 1493 - 1541 PreAge Central Thesis Due to the new possibilities in medicine and pharmacotherapy the life expectancy will soon rise to 1000 years PreAge 4 Renaissance Luigi Cornaro: The Father of Caloric Restriction Luigi Cornaro 1475 - 1566 Renaissance Ponce de Leon: In Search of the Fountain of Youth 1460-1521 La vita sobria PreAge The 18th Century Hufeland: The Leading Figure of Vitalism PreAge The 18th Century Hufeland: Makrobiotik. Die Kunst, das menschliche Leben zu verlängern Jena 1796 Strengthening of the „Vital Force“ is the key to longevity An international Anti-Aging bestseller Christoph Wilhelm Hufeland (1762-1836) PreAge The 18th Century J.W. Goethe: Hufeland´s most prominent Patient PreAge The 19th Century Brown-Séquard: The Founder of Modern Endocrinology An example of Lecture „On some effects, shown in men by the subcutaneous injection of watery extracts of dog and guinea pig testicles“ Paris, 1. Juni 1889 „successfull aging“ Johann Wolfgang von Goethe 1749 - 1832 Charles-Eduard Brown-Séquard (1817-1894) PreAge PreAge 5 The 19th Century The first Hormonal Anti-Aging Hype The 19th Century Empress Elisabeth: Austrian Idol of Beauty Sisi: An early Case of Eating Disorder and Anti-Aging Paranoia? „It beats Brown-Sequard – Tanner‘s infallible elixir of life for pension grabbers only“. Karikatur von Louis Dalrymple, 1889 (1837-1898) PreAge The 20th Century The Testicle Transplanters I PreAge The 20th Century The Testicle Transplanters I Worldwide transplantations of monkey testicles Serge Voronoff (1866-1951) Before After PreAge PreAge The 20th Century The Testicle Transplanters II The 20th Century Monkey glands for Millionaires John Romulus Brinkley 1885 - 1942 PreAge PreAge 6 The 20th Century Eugen Steinach: A Viennise Pioneer The 20th Century A blockbuster Ufa – Production, 1922 The ligature of the Ductus deferens as an Anti-Aging therapy Eugen Steinach (1861-1944) PreAge The 20th Century Ilja Mechnikov: The Founder of Probiotic Research PreAge The 20th Century Paul Niehans: The Founder of the“Living Cell Therapy“ Father of Stem Cell Therapy or Voodoo-Doctor? Ilja Iljitsch Mechnikov (1845-1916) Yogurt, sour milk and kefir as longevity substances Paul Niehans (1882-1971) PreAge The 20th Century The Pope: Niehan‘s most prominent patient PreAge Anti-Aging Wilhelm Christoph Hufeland on the Art of Life Extension This problem has always attracted the brightest minds , is a playground for daydreamers, and the biggest temptation for crooks and quacks. Pope Pius XII (1876-1958) Hufeland: Makrobiotik, Jena 1796 PreAge PreAge 7 Prophets of „Radical Life Extension“ Anti-Aging-Medicine What´´s up for the future? Aubrey de Grey, Cambridge „Aging is a treatable disease“ PreAge PreAge Prophets of „Radical Life Extension“ Ray Kurzweil, New York „If you manage to survive the next 30 years, you wont have to die anymore“ PreAge PreAge Ray Kurzweil Vordenker des Transhumanismus Vorlesungen Leçon sur les maladies des villards et les maladies chroniques Paris, 1868 Jean-Martin Charcot (1825-1893) Ist Altern eine Krankheit an sich? Senectus ipsa morbus (Terenz) PreAge PreAge 8 Transhumanismus Transhumanismus Der Mensch nimmt seine Evulotion selbst in die Hand PreAge Wie human wird der Transhumanismus? PreAge „Wenn man sich denkt, wie wenig ein Naturmensch auf den Südseeinseln von Krankheiten weiß, und dagegen nun ein europäisches pathologisches Kompendium hält, wo sie regimenter- und kompanienweise aufmarschieren, und ihre Zahl sich auf viele Tausende beläuft, so erschrickt man davor, was durch Luxus, Sittenverderbnis, unnatürliche Lebensart und Ausschweifungen möglich geworden ist. Viele, ja wirklich die meisten dieser Krankheiten sind unsere eigene Schuld.“ Ch. W. Hufeland Makrobiotik. Die Kunst, das menschliche Leben zu verlängern Jena 1796 PreAge PreAge Radical Life Extension Audrey de Grey Arzt & Prävention April 2007 Ending Aging:„Wie wir 1000 Jahre alt werden können“ PreAge 9