List of all Publications

Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
Veröffentlichungen
2015
Zapf-Gottwick, R., Koch, M., Fischer, K., Schwerdt, F., Hamann, L., Kranert, M., Metzger, J.
W. and Werner, J. H. (2015): Leaching Hazardous Substances out of Photovoltaic Modules.
International Journal of Advanced Applied Physics Research, cosmos Scholars Publishing
House 2(2): 7-14.
Gerbersdorf, S., Cimatoribus, C., Class, H., Engesser, K.-H., Helbich, S., Hollert, H., Lange,
C., Kranert, M., Metzger, J. W., Nowak, W., Seiler, T.-B., Steger, K., Steinmetz, H. and
Wieprecht, S. (2015): Anthropogenic Trace Componounds (ATCs) in aquatic habitats –
Research needs on sources, fate, detection and toxicity to ensure timely elimination
strategies and risk management. Environment International 79(2015): 85-105.
http://dx.doi.org/110.1016/j.envint2015.1003.1011.
2014
Lange, C., B. Kuch and J. W. Metzger (2014). "Occurence and fate of synthetic musk
fragrances in a small German river." Hazardous Materials:
http://dx.doi.org/10.1016/j.jhazmat.2014.1006.1027.
Lange, C.; Kuch, B.; Metzger, J. W. (2014): Estrogenic activity of constituents of underarm
deodorants determined by E-Screen assay. Chemosphere 108 (August 2014), 101-106.
http://dx.doi.org/10.1016/j.chemosphere.2014.02.082.
Lange, C.; Kuch, B.; Metzger, J. W. (2014): Determination of the Occurrence and Elimination
of Endocrine Disrupting Compounds (EDCs) in Municipal Wastewater Treatment Plants
(WWTP). Computational Water, Energy, and Environmental Engineering, 3, 1-7 (Published
Online January 2014).
Launay, M., Kuch, B., Lange, C., Schlichtig, B., Dittmer, U., Metzger, J. W. and Steinmetz,
H. (2014): Anwendung von Leitparametern zur Abschätzung des Verhaltens organischer
Spurenstoffe in einem urban geprägten Gewässer. KA – Korrespondenz Abwasser, Abfall,
(61): Nr.11, 1013-1018, DOI: 1010.3242/kae2014.1011.1005.
2013
Sasu, S. ; Metzger, J. W.; Kranert, M.; Kümmerer, K. (2013): Biodegradation of the
Antituberculosis Drug Isoniazid in the Aquatic Environment. CLEAN - Air Water and Soil,
Accepted Article. Online ISSN: 1863-0669.
Lange, C.; Kuch, B.; Metzger, J. W. (2013): Untersuchung von Mineralwässern auf
estrogene Wirkung mittels E-Screen-Assay. GWF-Wasser/Abwasser, 09/2013 (154), 982987.
Lange, C.; Kuch, B.; Metzger, J. W. (2013): Determination of the occurrence and elimination
of endocrine disrupting compounds (EDCs) in municipal wastewater treatment plants
1
Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
(WWTP). Istanbul International Solid Waste, Water And Wastewater Congress,Turkey,
Istanbul, 22.-24.05.2013, Book of Abstracts.
Lange, C.; Kuch, B.; Pfeiffer, J. A.; Podlipsky-Sanchez, J.; Hetzenauer, H.; Schroeder, H.;
Metzger, J. W. (2013): Biomonitoring of Polybrominated Diphenyl Ethers and Polychlorinated
Biphenyls in Fishes of Lake Constance, Germany. 14th EuCheMS International Conference
on Chemistry and the Environment, Spain, Barcelona, 25.-28.06.2013, Book of Abstracts,
514.
Triebskorn, Rita; Amler, Klaus; Blaha, Ludek; Gallert, Claudia; Giebner, Sabrina; Güde,
Hans; Henneberg, Anja; Hess, Stefanie; Hetzenauer, Harald; Jedele, Klaus; Jung, RalphMichael; Kneipp, Sven; Köhler, Heinz-R; Krais, Stefanie; Kuch, Bertram; Lange, Claudia;
Löffler, Herbert; Maier, Diana; Metzger, Jörg W.; Müller, Michael; Oehlmann, Jörg;
Osterauer, Raphaela; Peschke, Katharina; Raizner, Jürgen; Rey, Peter; Rault, Magali;
Richter, Doreen; Sacher, Frank; Scheurer, Marco; Schneider-Rapp, Jutta; Seifan, Merav;
Spieth, Markus; Vogel, Hans-Joachim; Weyhmüller, Michael; Winter, Josef; Wurm, Karl
(2013): SchussenAktivplus: reduction of micropollutants and of potentially pathogenic
bacteria for further water quality improvement of the river Schussen, a tributary of Lake
Constance, Germany. Environmental Science Europe 25(2), doi:10.1186/2190-4715-25-2.
2012
Metzger, J. W.; Amaral, K.; Erthal, L. A. V. (2012): Análise do uso de osmose reversa em
uma indústria automotiva. Hydro No 74, 24-29.
2009
Kuch, Bertram; Kern, Frieder; Metzger, Jörg W.; Trenck, Karl Theo von der (2009): Effectrelated monitoring: estrogen-like substances in groundwater. chemical and biological
environmental monitoring.
2008
Klaus, Cornelia; Metzger, Jörg W. (2008): Hormone im Abwasser - Untersuchungen zum
Vorkommen und der Elimination von estrogenen aktiven Substanzen während der
Kläranlagenpassagen
mit
dem
E-Screen-Assay.
KAKorrespondenz
Abwasser/Abfall.(vorraussichtlich im II. Quartal 2008).
Metzger, Jörg W. (2008): Anthropogene Spurenstoffe im Wasserkreislauf - Gefahr für die
Wasserversorgung? Stuttgarter Berichte der Siedlungswasserwirtschaft Band 192, 41-47.
Pfeiffer, Jörg; Kuch, Bertram; Hetzenauer, Harald; Löffler, Herbert; Metzger, Jörg W. (2008):
Organische Schadstoffe im Bodensee. Labor Praxis 4, 30-32.
Stäb, Jessica; Kuch, Bertram; Rupp, Silke; Fischer, Klaus; Kranert, Martin; Metzger, Jörg W.
(2008): Determination of Organic Contaminants in Compost and Digestates in BadenWürttemberg, South-West Germany. Proceedings of the international congress Codis 2008,
73-77.
2
Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
Trautwein, Christoph; Kümmerer, Klaus; Metzger, Jörg W. (2008): Aerobic biodegradability
of the calcium channel antagonist verapamil and identification of a microbial dead-end
transformation product studied by LC-MS/MS. Chemosphere 72, 442-450.
2006
Metzger, Jörg W. (2006): Organische Spurenstoffe im Wasserkreislauf - (K)ein Problem für
das Trinkwasser? Begleitband der Vortragsreihe Stiftung für Lebensmittelsicherheit und
Verbraucherschutz, 26-29.
2005
Rupp, Silke; Metzger, Jörg W. (2005): Brominated-chlorinated diphenylethers formed by
thermolysis of polybrominated diphenyl ethers at low temperatures. Chemosphere 60(11),
1644-1651.
2004
Mößmer, P.; Kuch, Bertram; Spengler, Peter; Willems, M.; Metzger, Jörg; Janke, H. D.
(2004): Residual concentration of estrogenic compounds in the effluent of two different
activated sludge plants. GWF, Wasser/Abwasser 145(4), 251-262.
Mößmer, P.; Kuch, Bertram; Spengler, Peter; Willems, M.; Metzger, Jörg; Janke, H. D.
(2004): Untersuchungen zum Restgehalt an estrogen wirkenden Substanzen (EWS) im
gereinigten Ablauf von zwei funktionell unterschidlichen kommunalen Belebungsanlagen.
GWF, Wasser/Abwasser 145(4), 251-262.
Schultis, Tanja; Kuch, Bertram; Kern, Andrea; Metzger, Jörg W. (2004): Potential
accumulation of estrogenic substances in biofilms and aquatic plants collected in sewage
treatment plant (STP) and receiving water. Organohalogen Compounds 66, 3004-3008.
Schultis, Tanja; Metzger, Jörg W. (2004): Determination of estrogenic activity by LYESassay (yeast estrogen screen-assya assisted by enzymatic digestion with lyticase).
Chemosphere 57, 1649-1655.
Spengler, Peter; Metzger, Jörg (2004): Analysis of hormonally active agents in sewage
treatment plant effluents, influents amd in surface waters. Analytical Workshop on Endocrine
Disruptors. P. Werner B. Bilitewski, D. Weltin: Dresden University of Technology. 18: 53-73.
Wurst, Friedrich Martin; Wiesbeck, Gerhard A.; Metzger, Jörg W.; Weinmann, Wolfgang;
Graf, Marc (2004): On sensitivity, specificity, and the influence of various parameters on
ethyl glucuronide levels in urine-results from the WHO/ISBRA study. Alcoholism: Clinical and
Experimental Research 28(8), 1220-1228.
2003
3
Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
Baumeister, F., König, A., Ender, O., Metzger, J. W. (2003): Bewertung eines neuen
Nitrifikationshemmtests durch Vergleich mit der Methode nach DIN EN ISO 9509.
Korrespondenz Abwasser 50(1), 39-44.
Giger, W.; Field, J.A.; Reinhard, M.; Schultz, M.; Barofsky, D.; Metzger, J. W.; Kuch, B.;
Keppler, F. (2003): Focal point: Environmental analytical chemistry: Emerging contaminants
and water analysis. CHIMIA, r+d in life sciense 57(1-2), 22-34.
Metzger, Jörg W. (2003): Klärschlamm als Düngemittel - Drei Beiträge in der Buchreihe
VOM WASSER im Rückblick - Sewage Sludge as Fertilizer - Looking Back at three
Contributions in the Book Series VOM WASSER. Vom Wasser 101, 69-76.
Metzger, Jörg W.; Kuch, Bertram (2003): Organic Flame Retardants in Wastewater
Treatment Plants. CHIMIA, r+d in life sciense 57(1/2), 24-26.
Spengler, Peter; Böhmer, Jürgen; Schlichtig, Birgit; Metzger, Jörg; Rott, Ulrich (2003):
Hormonelle Belastungen von Schönungsteichen. Wasser - Abwasser - GWF 144(12), 834842.
Spengler, Peter; Scholz-Muramatsu, Heidrun; Gaiser, Suse; Metzger, Jörg W. (2003): The
fate of some xenoestrogenic substances in wastewater treatment plants. GWF,
Wasser/Abwasser 4(144), 284-291.
Spengler, Peter; Scholz-Muramatsu, Heidrun; Gaiser, Suse; Metzger, Jörg W. (2003):
Verbleib ausgewählter Xenoestrogene in der Kläranlage - The fate of some xenoestrogenic
substances in wastewater treatment plants. Wasser - Abwasser - GWF 144(4), 284-291.
2002
Baumeister, F., König, A., Metzger, J. W. (2002): Drei Testsysteme zur Bestimmung der
Nitrifikationshemmung in Abwässern - Vergleichende Untersuchungen mit einem
Respirometer, einem Biosensor und der Methode nach EN ISO 9509. Korrespondenz
Abwasser 49(8), 1086-1095.
Bolz, Ulrike; Kuch, Bertram; Metzger, Jörg W.; Körner, Wolfgang (2002): Eintrag/AustragBilanzierung der estrogenen Gesamtaktivität in Kläranlagen mit unterschiedlicher
technischer Ausstattung mittels eines Bioassays. Vom Wasser 98, 81-90.
Feurle, Gerhard E.; Metzger, Jörg W.; Grudinki, Alexandra; Hamscher, Gerd (2002):
Interaction of xenin with the neurotensin receptor of guinea pig enteral smooth muscles.
Peptides 23(3), 523-529.
Feurle, Gerhard E.; Metzger, Jörg W.; Grudinki, Alexandra; Hamscher, Gerd (2002):
Interaction of xenin with the neurotensin receptor of guinea pig enteral smooth muscles.
Peptides 23(8), 1519-1525.
4
Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
Hegemann, Werner; Busch, Kerstin; Spengler, Peter; Metzger, Jörg W. (2002): Einfluss der
Verfahrenstechnik auf die Eliminierung ausgewählter Estrogene und Xenoestrogen in
Kläranlagen - ein BMBF Verbundprojekt - Ergebnisse von Stufenbeprobungen auf
kommunalen Kläranlagen. Wasser - Abwasser - GWF 145(5), 422-428.
Link, Andreas; Spengler, Peter; Metzger, Jörg W. (2002): Bildung von 4Nonylphenoxyessigsäure (NP1EC) aus 4-Nonylphenolpolyethoxylaten (NPnEO) im
Abwasser - on-line-Kopplung eines Belebtschlamm-Batchreaktors mit HPLC-MS/MS. Vom
Wasser 98, 13-28.
Metzger, Jörg W.; Schneider, Carmen; Schullerer, Susanne; Spengler, Peter; Körner,
Wolfgang; Bolz, Ulrike; Kuch, Bertram; Brauch, Heinz-Jürgen; Lange, Frank Th.; Sacher,
Frank (2002): Bestimmung endokrin wirksamer Substanzen und Pharmaka in der
aquatischen Umwelt. KTBL-Schrift 404, 117-130.
Schmid, Dietmar; Behnke, Beate; Metzger, Jörg W.; Kuhn, Reinhard (2002): Nano-HPLCmass spectrometry and MEKC for the analysis of oligosaccarides from human milk.
Biochemical Chromatography 16, 151-156.
Schullerer, Susanne; Spengler, Peter; Metzger, Jörg W. (2002): Einfluss unterschiedlicher
Reinigungstechniken in der Abwasserbehandlung auf die Konzentration von Estrogenen im
Abwasser. Vom Wasser 98, 65-80.
Schultis, Tanja; Spengler, Peter; König, Andreas; Metzger, Jörg Wolfgang (2002):
Bestimmung der östrogenen Aktivität von Umweltproben mittels Rezeptorbindung
(Östrogenrezeptoren ER-alpha und ER-beta) und Fluoreszenzpolarimetrie. Vom Wasser 98,
1-12.
Wurst, Friedrich Martin; Metzger, Jörg W. (2002): The ethanol conjugate ethyl glucuronide is
a useful marker of recent alcohol consumption. Alcoholism: Clinical and Experimental
Research 26(7), 1114-1119.
2001
Knoche, G., Graf, I., Joas, G., König, A. und J.W. Metzger (2001): Vergleich von drei
Testverfahren zur Bestimmung des Biochemischen Sauerstoffbedarfs in wässrigen Proben.
Vom Wasser 97, 51-62.
Koch, M., Metzger. J.W. (2001): Festlegung von Vorgabewerten bei Ringversuchen zur
Eignungsprüfung von Laboratorien. Vom Wasser 96, 55-62.
Koch, Michael; Metzger, Jörg W. (2001): Definition of assigned values for proficiency tests in
water analysis. Accred. Qual. Assur. 6, 181-185.
Körner, Wolfgang; Spengler, Peter; Bolz, Ulrike; Schuller, Winfried; Hanf, Volker; Metzger,
Jörg W. (2001): Substances with estrogenic activity in effluents of sewage treatment plants
5
Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
in southwestern Germany. Part I: Chemical analysis. Environ. Toxicol. Chem. 20(10), 21332141.
Körner, Wolfgang; Spengler, Peter; Bolz, Ulrike; Schuller, Winfried; Hanf, Volker; Metzger,
Jörg W. (2001): Substances with estrogenic activity in effluents of sewage treatment plants
in southwestern Germany. Part II: Biological analysis. Environ. Toxicol. Chem. 20(10), 21422151.
Möhle, Edda; Metzger, Jörg (2001): Drugs in municipal sewage effluents: Screening and
biodegradation studies. ACS Symposium Series 791, 192-205.
Schmid, Dietmar G.; Behnke, Beate; Kempter, Christoph; Metzger, Jörg W.; Kuhn, Reinhard
(2001): Nano-HPLC of Oligosaccarides - Method Development and Optimization.
Mikrochimica Acta 137, 111-118.
Schneider, C.; Möhle, E.; Stenz, G.; Krauß, P.; Metzger, J. W. (2001): Arzneimittel in
Siedlungsabfällen und in Deponiesickerwässern. Müll und Abfall 6, 362 - 369.
Spengler, Peter; Körner, Wolfgang; Metzger, Jörg Wolfgang (2001): Substances with
estrogenic activity in effluents of sewage treatment plants in southwest Germany. Part I:
Chemical Analysis. Environmental Toxicology and Chemistry 20(10), 2133-2141.
Süßmuth, Roderich D.; Metzger, Jörg W.; Jung, Günther (2001): Structure elucidation and
chemical
synthesis
of
microbial
metabolites.
Sonderdruck:
Deutsche
Forschungsgemeinschaft-DFG-Microbial Fundamentals of Biotechnology, 318-342.
2000
Möhle, Edda; Metzger, Jörg (2000): Drugs in municipal sewage effluents: Screening and
biodegradation studies. ACS Division of Environmental Chemistry Preprints 40(1), 114-116.
Schmid, Markus; Twachtmann, Ulf; Klein, Michael; Strous, Marc; Juretschko, Stefan; Jetten,
Mike; Metzger, Jörg W.; Schleifer, Karl-Heinz; Wagner, Michael (2000): Molecular evidence
for genus level diversity of bacteria capable of catalyzing anaerobic ammonium oxidation.
Systematic and applied microbiology 23, 93-106.
Wurst, Friedrich Martin; Kempter, Christoph; Metzger, Jörg W.; Seidl, Stephan; Alt, Andreas
(2000): Ethyl glucuronide: a marker of recent alcohol consumption with clinical and forensic
implications. Elsevier - Alcohol 20, 111-116.
Wurst, Friedrich Martin; Seidl, Stephan; Alt, Andreas; Metzger, Jörg W. (2000): Der direkte
Ethanolmetabolit Ethylglucuronid. Psychiatrische Praxis 27, 367-371.
1999
Behnke, Beate; Metzger, Jörg W. (1999): Tryptic digest mapping by gradient capillary
electrochromatography. Electrophoresis 20, 80-83.
6
Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
König, A.; Bachmann, T.T.; Metzger, J.W.; Schmid, R.D. (1999): Disposable sensor for
measuring the biochemical oxygen demand for nitrification and inhibition of nitrification in
wastewater. Appl. Microbiol. Biotechnol. 51, 112-117.
Körner, Wolfgang; Hanf, Volker; Schuller, Winfried; Kempter, Christoph; Metzger, Jörg;
Hagenmaier, Hanspaul (1999): Development of a sensitive E-screen assay for quantitative
analysis of estrogenic activity in municipal sewage plant effluents. Sci. Total Environ. 225,
33-48.
Körner, Wolfgang; Spengler, Peter; Bolz, Ulrike; Hagenmaier, Hanspaul; Metzger, Jörg
(1999): Monitoring of estrogenic substances in sewage plant effluents by biological and
chemical analysis. Organohalogen Compounds 42, 29-32.
Möhle, Edda; Kempter, Christoph; Kern, Andrea; Metzger, Jörg (1999): Untersuchungen
zum Abbau von Pharmaka in kommunalen Kläranlagen mit HPLC- ElektosprayMassenspektrometrie. - Examination of the degradation of drugs in municipal sewage plants
using liquid chromatographa- electospray mass spectrometry. Acta Hydrochemica et
Hydrobiologica 27(6), 430-436.
1998
Heidrich, Christoph; Pag, Ulrike; Michaele, Josten; Metzger, Jörg; Jack, Ralph. W.;
Bierbaum, Gabriele; Jung, Günther; Sahl, Hans-Georg (1998): Isolation, Characterization,
and Heterologous Expression of the Novel Lantibiotic Epicidin 280 and Analysis of Its
Biosynthetic Gene Cluster. Applied and Environmental Microbiology 64(9), 3140-3146.
Höltzel, Alexandra; Kempter, Christoph; Metzger, Jörg W.; Jung, Günther; Groth, Ingrid;
Fritz, Thomas; Fiedler, Hans-Peter (1998): Spirofungin, a new antifungal antibiotic from
Streptomyces violaceusniger Tü 4113. J. Antibiotics 51(8), 699-707.
König, Andreas; Riedel, Klaus; Metzger, Jörg W. (1998): A microbial sensor for detecting
inhibitors of nitrification in wastewater. Biosensors & Bioelectronics 13, 869-874.
Schönharting, Barbara; Ruxandra, Rehner; Jörg W., Metzger; Krauth, Karlheinz; Rizzi,
Manfred (1998): Release of nitrous oxide (N2O) from denitrifying activated sludge caused by
H2S-containing wastewater: quantification
and application of a new mathematical model. Water Science and Technology 38(1), 237–
246.
1997
Haap, Wolfgang J.; Metzger, Jörg W.; Kempter, Christoph; Jung, Günther (1997):
Composition and purity of combinatorial aryl ether collections analyzed by electrospray mass
spectrometry. Mol. Diversity 3, 29-41.
7
Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
Huber, Alexander; Merz, Wolfgang; Metzger, Jörg W. (1997): Quantitative recoveries of
organically bound sulfur adsorbed on active carbon (AOS) obtained by a new combustion
technique. GIT Laborfachzeitschrift Special Edition (4/99), 102-104.
Kempter, C.; Kaiser, D.; Haag, S.; Nicholson, G.; Gnau, V.; Walk, T.; Gierling, K.H.; Decker,
H.; Zähner, H.; Jung, G.; Metzger, J.W. (1997): CDA: Calcium-Dependent Peptide
Antibiotics from Streptomyces coelicolor A3(2) Containing Unusual Residues. Angew.Chem.
36(5), 498-501.
Kienle, S.; Wiesmüller, K.-H.; Brünjes, J.; Metzger, J.W.; Jung, G. (1997): MS-Pep: a
computer program for the interpretation of mass spectra of peptide libraries. Fresenius J.
Anal. Chem. 359, 10-14.
König, Andreas; Secker, Jutta; Riedel, Klaus; Metzger, Jörg W. (1997): A microbial sensor
for measuring inhibitors and substrates for nitrification in wastewater. Amer. Lab. 29(24), 1221.
Subramaniam-Niehaus, Bhavani; Schneider, Thomas; Metzger, Jörg W.; Wohlleben,
Wolfgang (1997): Isolation and analysis of moenomycin and its biosynthetic intermediates
from Streptomyces ghanaensis (ATCC 14672) wildtype and selected mutants. Zeitschrift für
Naturforschung Section C- Journal of Biosciences 52c(3-4), 217-226.
1996
Feurle, G.E.; Klein, A.; Hamscher, G.; Metzger, J.W.; Schuurkes, A.J. (1996): Neurokinetic
and myokinetic effects of the peptide xenin on the motility of the small and large intestine of
Guinea pig. J. of Pharmacology and Experimental Therapeutics 278(2), 654-661.
Fiedler, H.-P.; Nega, Mulugeta; Pfefferle, C.; Groth, I.; Kempter, C.; Stephan, H.; Metzger,
J.W. (1996): Kanchanamycins, new polyol macrolide antibiotics produced by Streptomyces
olivaceus Tü 4018 I. Taxonomy, fermentation, isolation and biological activities. J.
Antibiotics 49(8), 758-764.
Kempter, Christoph; Kupke, T.; Kaiser, D.; Metzger, J. W.; Jung, . G. (1996): Thioenols from
Peptidyl Cysteines: Oxidative Decarboxylation of a laC-Labeled Substrate. Angewandte
Chemie (International Edition in English) 35(18), 2104-2107.
Kuipers, O.P.; Bierbaum, G.; Ottenwälder, B.; Dodd, H.M.; Horn, N, .; Metzger, J.; Kupke, T.;
Gnau, V.; Bongers, R.; van den Bogaard, P.; Kosters, H.; Rollema, H.S.; de Vos, W.M.;
Siezen, R.J.; Jung, G.; Götz, F.; Sahl, H.-G.; Gasson, M.J. (1996): Protein engineering of
lantibiotics. Antonie van Leeuwenhoek 69, 161-170.
Ness, A.; Metzger, J.W.; Schmidt, P.C. (1996): Isolation, identification and stability of 8desacetylmatricine, a new degradation product of matricine. Pharma. Acta Helv. 71, 265271.
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Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
Pfefferle, C.; Kempter, C.; Metzger, J.W.; Fiedler, H.-P. (1996): (E)-4-Oxonon-2-enoic acid,
an antibiotically active fatty acid produced by Streptomyces olivaceus Tü 4018. J. Antibiotics
49(8), 826-828.
Rollema, H.S.; Metzger, J.W.; Both, P.; Kuipers, O.P.; Siezen, R.J. (1996): Structure and
biological activity of chemically modified nisin A species. Eur. J. Biochem. 241, 716-722.
Schliemann, W.; Joy, R.W.; Komamine, A.; Metzger, J.; Nimitz, M.; Wray, V.; Strack, D.
(1996): Betacyanins from plants and cell cultures of Phytolacca Americana. Phytochemistry
42(4), 1039-1046.
Stephan, H.; Kempter, C.; Metzger, J.W.; Jung, G.; Potterat, O.; Pfefferle, C.; Fiedler, H.-P.
(1996): Kanchanamycins, new polyol macrolide antibiotics produced by Streptomyces
olivaceus Tü 4018 II. Structure elucidation. J. Antibiotics 49(8), 765-769.
1995
Blum, S.; Fiedler, H.-P.; Groth, I.; Kempter, C.; Stephan, H.; Nicholson, G.; Metzger, J.W.;
Jung, G. (1995): Biosynthetic capacities of actimomycetes. 4. Echinoserine, a new member
of the quinoxaline group, produced by streptomyces tendae. J. Antibiotics 48(7), 619-625.
Dornberger, K.; Ihn, W.; Ritzau, M.; Gräfe, U.; Schlegel, B.; Fleck, W.F.; Metzger, J.W.
(1995): Chrysospermins, new peptaibol antibiotics from Apiocrea chrysosperma Ap101. J.
Antibiotics 48(9), 977-989.
Ettner, N.; Metzger, J.W.; Lederer, T.; Hulmes, J.D.; Kisker, C.; Hinrichs, W.; Ellestad, G.A.;
Hillen, W. (1995): Proximity mapping of the Tet repressor-tetracycline-Fe2+ complex by
hydrogen peroxide mediated protein cleavage. Biochemistry 34, 22-31.
Hamscher, G.; Meyer, H.E.; Metzger, J.W.; Feurle, G.E. (1995): Distribution, formation, and
molecular forms of the peptide xenin in various animals. Peptides 16, 791-797.
Metzger, J.W.; Beck-Sickinger, A.G.; Loleit, M.; Eckert, M.; Bessler, W.G.; Jung, G. (1995):
-terminus of the
cytochrome-subunit of the photoreaction centre of Rhodopeudomonas viridis enhance
murine splenocyte proliferation. J. Peptide Sci. 3, 184-190.
Ottenwälder, Birgit; Kupke, Thomas; Brecht, Susan; Gnau, Volker; Metzger, Jörg; Jung,
Günther; Götz, Friedrich (1995): Isolation and characterization of genetically engineered
gallidermin and epidermin analogs. J. Appl. Environm. Microbiol. 61, 3894-3903.
Singh, D.G.; Lomako, J.; Lomako, W.M.; William, J.W.; Meyer, H.E.; Serwe, M.; Metzger, J.
-Glucosylarginine: a new glucose-protein bond in a self-glucosylating protein from
sweet corn. FEBS Letters 376, 61-64.
van de Kamp, M.; Horstink, L.M.; van den Hooven, H.W.; Konings, R.N.H.; Hilbers, C.W.;
Frey, A.; Sahl, H.-G.; Metzger, J.W.; van de Ven, F.J.M. (1995): Sequence analysis by NMR
9
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Prof. Dr. rer. nat. habil. Jörg W. Metzger
spectroscopy of the peptide lantibiotic epilancin K7 from Staphylococcus epidermis K7. Eur.
J. Biochem. 227, 757-771.
Zimmermann, N.; Metzger, J.W.; Jung, G. (1995): The tetracyclic lantibiotic actagardine: 1H
and 13C-NMR assignments and revised primary structure. Eur. J. Biochem. 228, 786-797.
1994
Baker, D.C.; Dougall, D.K.; Gläßgen, W.E.; Johnson, S.C.; Metzger, J.W.; Rose, A.; Seitz,
H.U. (1994): Effects of supplied cinnamic acids and biosynthetic intermediates on the
anthocyanins accumulated by wild carrot suspension cultures. Plant Cell Tiss. Org. Cult. 39,
79-91.
Heuer, S.; S., Richter; Metzger, J.W.; Wray, V.; Nimitz, M.; Strack, D. (1994): Betacyanins
from bracts of Bougainvillea glabra. Phytochemistry 37, 761-767.
Jack, R.W.; Carne, A.; Metzger, J.; Stefanovic, S.; Sahl, H.-G.; Jung, G.; Tagg, J. (1994):
Elucidation of the structure of SA-FF22, a lanthionine-containing antibacterial peptide
produced by Streptococcus pyogenes strain FF22. Eur. J. Biochem. 220, 455-462.
Kleine, B.; Rapp, W.; Wiesmüller, K.-H.; Edinger, M.; Beck, W.; Metzger, J.; Ataulakhanov,
R (1994): Lipopeptide-polyoxyethylene conjugates as mitogens and adjuvants. Immunobiol.
190, 53-66.
Metzger, Jörg W. (1994): Ladder sequencing of peptides and proteins - Acombination of
Edman degradation and mass spectrometry. Angewandte Chemie (International Edition in
English) 33(7), 723-725.
Metzger, J.W.; Kempter, C.; Wiesmüller, K.-H.; Jung, G. (1994): Electrospray mass
spectrometry and tandem mass spectrometry of synthetic multi-component peptide mixtures:
determination of composition and purity. Analytical Biochemistry 219(2), 261-277.
Metzger, J.W.; Stevanovic, S.; Brünjes, J.; Wiesmüller, K.-H.; Jung, G. (1994): Electrospray
mass spectrometry and multiple sequence analysis of synthetic peptide libraries. Methods: A
Companion to Methods in Enzymology 6, 425-431.
Meyer, H.E.; Heber, M.; Eisermann, B.; Korte, H.; Metzger, J.W.; Jung, G. (1994): Sequence
analysis of lantibiotics: novel derivatization procedures allow a fast access to complete
Edman degradation. Anal. Biochem. 223, 185-190.
Potterat, O.; Stephan, H.; Metzger, J.W.; Gnau, V.; Zähner, H.; Jung, G. (1994): Aborycin - a
tricyclic 21-peptide antibiotic isolated from Streptomyces griseoflavus. Liebigs Ann. Chem.,
741-743.
Potterat, O.; Zähner, H.; Metzger, J.W.; Freund, S. (1994): Metabolic products of
microorganisms, part 269. 5-Phenylpentadienoic-acid derivatives from Streptomyces sp.
Helv. Chim. Acta 77(2), 569-574.
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Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
1993
Bessalle, R.; Gorea, A.; Shalit, I.; Metzger, J.W.; Dass, C.; Desiderio, D.M.; Fridkin, M.
(1993): Structure-function studies of amphiphilic antibacterial peptides. J. Med. Chem. 36,
1203-1209.
Glässgen, W.E.; Metzger, J.W.; Heuer, S.; Strack, D. (1993): Betacyanins from fruits of
Basella rubra. Phytochemistry 33, 1525-1527.
Kupke, T.; Stevanovic, S.; Ottenwälder, B.; Metzger, J.W.; Jung, G.; Götz, F. (1993):
Purification and characterization of EpiA, the peptide substrate for post-translational
modification involved in epidermin biosynthesis. FEMS Microbiol. Lett. 112, 43-48.
Metzger, J.W.; Sawyer, W.H.; Wille, B.; Biesert, L.; Bessler, W.G.; Jung, G. (1993):
Interaction of immunologically active lipopeptides with membranes. Biochim. Biophys. Acta
1149, 29-39.
Metzger, Jörg W.; Wiesmüller, K.-H.; Gnau, V.; Brünjes, J.; Jung, . G. (1993): Ion-spray
mass spectrometry an high performance liquid chromatography - Mass spectrometry of
synthetic peptide libraries. Angewandte Chemie (International Edition in English) 32(6), 894896.
Mock, H.-P.; Wray, V.; Beck, W.; Metzger, J.W.; Strack, D. (1993): Coumaroylaspartate
from cell suspension cultures of Arabidopsis thaliana. Phytochemistry 34, 157-159.
Petersen, F.; Zähner, H.; Metzger, J.W.; Freund, S.; Hummel, R.-P. (1993): Germicidin, an
autoregulative germination inhibitor of Streptomyces viridochromogenes NRRL B-1551. J.
Antibiotics 46, 1126-1138.
Petersen, M.; Metzger, J.W. (1993): Identification of the reaction products of rosmarinic acid
synthase from cell cultures of Coleus blumei by ion-spray mass spectrometry and tandem
mass spectrometry. Phytochemical Anal. 4, 131-134.
Stevanovic, S.; Wiesmüller, K.-H.; Metzger, J.; Beck-Sickinger, A.G.; Jung, G. (1993):
Natural and synthetic peptide pools: characterization by sequencing and electrospray mass
spectrometry. Bioorg. Med. Chem. Lett. 3, 431-436.
1992
Feurle, G.E.; Hamscher, G.; Kusiek, R.; Meyer, H.E.; Metzger, J.W. (1992): Identification of
xenin, a xenopsin-related peptide, in the human gastric mucosa and its effect on exocrine
pancreatic secretion. J. Biol. Chem. 267, 22305-22309.
Gläßgen, W.E.; Seitz, H.U.; Metzger, J.W. (1992): High-performance liquid chromatography
- ion spray mass spectrometry and tandem mass spectrometry of anthocyanins from plant
tissues and cell cultures of Daucus carota L. Biol. Mass Spectrom. 21, 271-277.
11
Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
Gläßgen, W.E.; Wray, V.; Strack, D.; Metzger, J.W.; Seitz, H.U. (1992): Anthocyanins from
cell suspension cultures of Daucus carota. Phytochemistry 31, 1593-1601.
Heilmeyer, Jr., L.M.G.; Serwe, M.; Weber, C.; Metzger, J.; Hoffmann-Posorske, E.; Meyer,
muscle phosphorylase kinase: localization by conversion to S-ethylcysteine and by tandem
mass spectrometry. Proc. Natl. Acad. Sci. 89, 9554-9558.
Heuer, S.; Wray, V.; Metzger, J.W.; Strack, D. (1992): Betycyanins from flowers of
Gomphrena globosa. Phytochemistry 31, 1801-1807.
Metzger, Jörg W.; Beck, W.; Jung, . G. (1992): Ion-spray mass spectrometry of lipopeptide
vaccines. Angewandte Chemie (International Edition in English) 31(2), 226-228.
Offermanns, S.; Seifert, R.; Metzger, J.W.; Jung, G.; Lieberknecht, A.; Schmidt, U.; Schultz,
G. (1992): Lipopeptides are effective stimulators of tyrosine phosphorylation in human
myeloid cells. Biochem. J. 282, 551-557.
Seifert, R.; Serke, S.; Huhn, D.; Bessler, W.G.; Hauschildt, S.; Metzger, J.; Wiesmüller, K.H.; Jung, G. (1992): Incomplete functional differentiation of HL-60 leukemic cells by synthetic
lipopeptides. Partial inhibition by pertussis toxin of enhanced superoxide formation. Eur. J.
Biochem. 203, 143-151.
Strack, D.; Wray, V.; Metzger, J.W.; Grosse, W. (1992): Two anthocyanins acylated with
gallic acid from the leaves of Victoria amazonica,. Phytochemistry 31, 989-991.
1991
Beck-Sickinger, A.G.; Schnorrenberg, G.; Metzger, J.; Jung, G. (1991): Sulfonation of
arginine residues as side reaction in Fmoc-peptide synthesis. Int. J. Peptide Prot. Res. 38,
25-31.
Berner, I.; Greiner, M.; Metzger, J.; Jung, G.; Winkelmann, G. (1991): Identification of
enterobactin and linear dihydroxybenzoylserine compounds by HPLC. Biol. Metals 4, 113118.
Drechsel, H.; Metzger, J.; Freund, S.; Jung, G.; Boelaert, J.R.; Winkelmann, G. (1991):
Rhizoferrin - a novel siderophore from the fungus Rhizopus microsporus
var.
rhizopodiformis. Biol. Metals 4, 238-243.
Falk, K.; Rötzschke, O.; Deres, K.; Metzger, J.; Jung, G.; Rammensee, H.G. (1991):
Identification of naturally processed viral nonapeptides allows their quantification in infected
cells and suggests an allele-specific T cell epitope forecast. J. Exp. Med. 174, 425-434.
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Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
Heuer, S.; Wray, V.; Metzger, J.; Strack, D. (1991): Modern spectroscopic methods in the
structural elucidation of betacyanins from Gomphrena globosa. Planta Medica 57(2), A121A122.
Metzger, J.; Jung, G.; Bessler, W.G.; Hoffmann, P.; Strecker, M.; Lieberknecht, A.; Schmidt,
U. (1991): Lipopeptides containing 2-palmitoyl-6,7-bis(palmitoyloxy)-heptanoic acid:
synthesis, stereospecific stimulation of B-lymphocytes and macrophages, and adjuvanticity
in vivo and in vitro. J. Med. Chem. 34, 1969-1974.
Metzger, J.; Wiesmüller, K.-H.; Schaude, R.; Bessler, W.G.; Jung, G. (1991): Synthesis of
novel immunologically active tripalmitoyl-S-glycerylcysteinyl lipopeptides as useful
intermediates for immonogen preparations. Int. J. Peptide Prot. Res. 37, 46-57.
Metzger, J.W.; Jung, M.; Schmalzing, D.; Bayer, E.; Schurig, V. (1991): Analysis of
cyclomalto-oligosaccharides (cyclodextrins) and derivatives by ion spray mass spectrometry.
Carbohydrate Res. 222, 23-35.
Metzger, J.W.; Wiesmüller, K.-Fmoc protected
derivatives of S-(2,3-dihydroxypropyl)-cysteine and their application in peptide synthesis. Int.
J. Peptide Prot. Res. 38, 545-554.
Schmidt, U.; Lieberknecht, A.; Kazmaier, U.; Griesser, H.; Jung, G.; Metzger, J. (1991):
Amino acids and peptides; 75. Synthesis of di- and trihydroxyamino acids - construction of
lipophilic tripalmitoyldihydroxy- -amino acids. Synthesis, 49-55.
Uhl, B.; Wolf, B.; Schwinde, A.; Metzger, J.; Jung, G.; Bessler, W.G.; Hauschildt, S. (1991):
Intracellular localization of a lipopeptide macrophage activator: immunocytochemical
investigations and EELS analysis on ultrathin cryosections of bone marrow-derived
macrophages. J. Leukocyyte Biol. 50, 10-18.
1990
Bessler, W.G.; Kleine, B.; Martinez Alonso, C.; Biesert, L.; Strecker, M.; Wiesmüller, K.-H.;
Metzger, J.; Jung, G. (1990): Biological activity of bacterial surface components: bacterial
extracts and defined bacterial cell wall components as immunomodulators. Lung Suppl:,
707-715.
Hoffmann, P.; Jimenez-Diaz, M.; Loleit, M.; Tröger, W.; Wiesmüller, K.-H.; Metzger, J.; Jung,
G.; I., Kaiser; Stöcklin, S.; Lenzner, S.; Peters, J.H.; Grimm, R.; Schäfer, E.; Bessler, W.G.
(1990): Preparation of human and murine monoclonal antibodies: antigens combined with or
conjugated to lipopeptides constitute potent immonogens for in vitro and in vivo
immunizations. Hum. Antibod. Hybridomas 1, 137-144.
Rötzschke, O.; Falk, K.; Deres, K.; Schild, H.; Norda, M.; Metzger, J.; Jung, G.;
Rammensee, H.-G. (1990): Isolation and analysis of naturally processed viral peptides as
recognized by cytotoxic T cells. Nature 348, 252-254.
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Veröffentlichungen
Prof. Dr. rer. nat. habil. Jörg W. Metzger
Schneider, C.H.; Rolli, H.; Metzger, J.; Jung, G. (1990): Anaphylactic properties of
monohaptenic dinitrophenylated tripalmitoyl-S-glyceryl-cysteinyl-lipopeptides. Mol. Immunol.
27, 241-245.
Seifert, R.; Schultz, G.; Richter-Freund, M.; Metzger, J.; Wiesmüller, K.-H.; Jung, G.;
Bessler, W.G.; Hauschildt, S. (1990): Activation of superoxide formation and lysozyme
release in human neutrophils by the synthetic lipopeptide Pam3Cys-Ser-(Lys)4. Biochem. J.
267, 795-802.
Weil, H.-P.; Beck-Sickinger, A.G.; Metzger, J.; Stevanovic; Josten, M.; Jung, G.; Sahl, H.-G.
(1990): Biosynthesis of the lantibiotic Pep5. Isolation and characterization of a prepeptide
containing dehydroamino acids. Eur. J. Biochem. 194, 217-223.
1989
Hoffmann, P.; Wiesmüller, K.-H.; Metzger, J.; Jung, . G.; Bessler, W.G. (1989): Induction of
tumor cytotoxicity in murine bone marrow-derived macrophages by two synthetic lipopeptide
analogues. Biol. Chem. Hoppe-Seyler 370, 575-582.
Reitermann, A.; Metzger, J.; Wiesmüller, K.-H.; Jung, G.; Bessler, W.G. (1989): Lipopeptide
derivates of bacterial lipoprotein constitute potent immune adjuvants combined or covalently
coupled to antigen or hapten. Biol. Chem. Hoppe-Seyler 370, 343-352.
Wolf, B.; Hauschildt, S.; Uhl, B.; J., Metzger; Jung, G.; Bessler, W.G. (1989): Localization of
the cell activator lipopeptide in bone marrow-derived macrophages by electron energy loss
spectroscopy (EELS). Immunol. Lett. 20, 121-126.
Wolf, B.; Uhl, B.; Hauschildt, S.; Metzger, J.; Jung, G.; Bessler, W. (1989): Interaction of the
lymphoid cell line BCL1 with lipopeptide analogues of bacterial lipoprotein: electron energy
loss spectroscopy (EELS) as a novel method to detect the distribution of the activator within
the cells. Immunobiol. 180, 93-100.
1987
Metzger, J.; G., Jung (1987): Elucidation of a side reaction during acylation of primary
amines with fatty acid chlorides. Liebigs Ann. Chem., 895-899.
Metzger, J.; Jung, G. (1987): Mycoloylpeptides and other lipopeptide adjuvants from higher
aldoketene dimers. Angew. Chem. Int. Ed. Engl. 26, 336-338.
Metzger, J.; Olma, A.; Leplawy, M.T.; Jung, G. (1987): Synthesis of a B-lymphocyte
-methylserine containing lipopentapeptide. Z. Naturfosch. 42 b, 1195-1201.
14