14513-Biostatistics statement - World Journal of Gastroenterology

NCT | Im Neuenheimer Feld 460 | D-69120 Heidelberg
Dr. med. Georg Martin Haag
Funktionsoberarzt
Medizinische Onkologie im NCT
Im Neuenheimer Feld 460
D-69120 Heidelberg
Telefon +49 6221 56-37630
Telefax +49 6221 56-33853
[email protected]
Editorial Board
World Journal of Gastroenterology
Heidelberg, 01.10.2014
Manuscript:
Palliative Chemotherapy for Gastroesophageal Cancer in Old and Very Old
Patients: A Retrospective Cohort Study at the National Center for Tumor
Diseases Heidelberg
Dear Editorial Board,
Please find enclosed our annotations concerning the statistical
analysis:
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Categorical data are presented in contingency tables with
frequencies and percentages.
Continuous data are summarized with at least the following: median,
minimum and maximum. Continuous data are compared using the
nonparametric Mann–Whitney U test. Frequency differences are
compared using the chi-squared test or Fisher’s exact test where
appropriate.
Progression free survival (PFS) is defined as time from the start of
palliative first-line treatment to documented tumor progression or
death. Overall survival (OS) is defined as the time from the start of
palliative first-line treatment to death. Residual survival (RS) is
defined as the time from the day of documented disease
progression to death.
Time-to event data are analyzed using standard methods, including
Kaplan-Meier product-limit estimate. Differences between the
actuarial estimates are tested using the log rank test.
Nationales Centrum für
Tumorerkrankungen Heidelberg
Im Neuenheimer Feld 460
D-69120 Heidelberg
www.nct-heidelberg.de
[email protected]
Interdisziplinäre Ambulanz
Telefon +49 6221 56-4801
Telefax +49 6221 56-8815
[email protected]
Onkologische Sprechstunden
Allgemeine Onkologie
CUP (Cancer of Unknown Primary)
Dermatologische Tumoren
Gastrointestinale Tumoren
Gynäkologische Tumoren
Gynäkologisch-genetische Sprechstd.
Kopf-Hals Tumoren
Kinderonkologie
Leukämie
Lymphome
Myelome
Neuroendokrine Tumoren
Neuroonkologie
Radioonkologie
Sarkome
Thorakale Tumoren
Urologische Tumoren
Beratungen
Krebsinformationsdienst (KID)
Ernährung
Psychoonkologie
Sozialdienst
Direktorium
Christof von Kalle, Prof. Dr.
Translationale Onkologie
Jürgen Debus, Prof. Dr.
Radioonkologie
Dirk Jäger, Prof. Dr.
Medizinische Onkologie
Peter Krammer, Prof. Dr.
Tumor Immunologie
Cornelia Ulrich, Prof. Dr.
Präventive Onkologie
Wolfgang Wick, Prof. Dr.
Neuroonkologie
Seite 2
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Cox Regression is used as a model for analyzing the effect of
several risk factors on survival.
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All statistical tests are two-tailored. Differences are considered
significant when p < 0.05.
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Statistical analyses were performed using SPSS statistical software,
Version 21.
Yours sincerely,
Georg Martin Haag,