Malignent pilo*tvryx,*i X

8rn. isu a,l6n'..*j**,$*i**,,;SG,,F*t€ logile Vete rln arla, Iora rls Z$OZ
!.hllgnlnt piloaratrieo*e {pi}om*trix,cercinomrl in a otd Engli*h
theepdog with pelric limb paralysie
Larrafti;
A. P.1', Voll,
#, &iwtn,F. lic.3
**. F*jal
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Bbrl , Fed t niv Rb Grte Sut(UFRGS),
Ategre,
!ath:,.Dept.
-sj{*VJ!
Dgryrtmgnt
d
Aninsl
Liledicite
Fed.
"-q
univ.
Rio GCe Sut (UFRGS}, porro n$re, nS, Atlzil
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porto
W.,'74,.{,,,4i;,}WtE44,Sq{a {t F$M},'$arrtc
LORETTlUFnGSveragd.wn
Maria, RS, brazil
lntroductiQn: Malignant $brmtricorna (pilgmatrix carcinoma) is a metastratic foilicular
fumor with exclusi@
tlffiiatkm. These maiignant hrmors arB \rery
Uf{$mmtrr a*d
.1.,@, seX lreed or site predilaction are ecarse-
m**d
inftn*i@;::
Malignent pilo*tvryx,*i
kmb paralysis is deecribcd ttere.
ffi
Hatertat anU t*ethoe: An eighl-pard mab
English Sheepdq rlas rebrred to a
brazilian unirrersity veterinary trcspffi on July 2oo2 with a history of lameness of fre
gagres*ing ro pehric timb paratysis.
{ght f{nd liryb
$ignalrnent,'hir$t9ry,
rrele r6trieveg ftrr lh6 reeiring
,:,6,,ti*tte*,*nd the brAin rlpre fixed in n{o
veterinarian,
brmalin, proessed br lrgtrt mrcrsspy ard siained with HE.
of
cliii.;'
Aftgr
;t.
X
Rmults: At palpation, a rrldrdffi grur4fr gf ro{Ehly 10 cm diameter was detected in the
dghf hip ioint Radlryraphic erarnketkxr dtf," pet*s reveatad oststytic and @rretive
lasi*l at d,Te right iliac eietfi.,A t€ry@ie $€rm6h of pnmary,o€teersartrrra'infttrding
the sciatis nerw rilas *gg€,,&*af*ai-s1s+,71aci,a,,r'rjli,+ircunserib€d, firm, *ig+based;
non-ulgrated mass of sFrexlryret ,,:15 c*r* oJ diamder bcatiad in the subqutanequs
tissua of the cervical regidr. The animal nes euthanized at orlnre/s request At
necropsy, ths ceMcel iumar frad *r:
cut surfafe wfth,sma[[, draity wtrite
bi, st&divlded by fria fanecslss, e*d,a-#l€ine. c.atet tit*e area filled udth yelknr,
crumbly matprial""Hisrnbgic6$y,
,*rsis[d of hry_o distirilct d]:twesl:
basalold cells and shadow celts; Extensive cell prolifuration of basophilic cells urere
obqar-ved at tho poriphery of the neoplasn w*Sr dtular atypia and 2 mim{io figures HPF.
Tfie cEnhl aresE of the tumer hd a rupt Sfiereflliatior to Any keratinized eosinsphilic
ghost ell* furmirg larW hem cysts. Caleif;catbn and bone meteplasia weslalso
sb$sv€d, $imilar bsions $rqe obstrvd :infilb*ti*g,fie ilium and adjoining lumbar,and
sacral wrteblag, $rie in€gisa gl &e lErtebrat eial, and the tungs. Thde pulrnonary
fiodul€g $6r$ randomly distrib{,ted,and had 0.Fi cm in diamet&. The diignosie ol
malignent,pilomatricoma wi$ metastasb tr,Forme and lungs uas flade on hietoloOic
*wnryrs
,*ta
examination.
...:.
Fhqfgpio$
Malignant pilematricoma should be di*tinguished forn it, benign
eountergart:Fiffi both have sirnilar morphological appearance, Di&r€nHion be(tiqen
pri*gry bone nm$esia and,,rsdoqndary metastatic tumors ehwld also be osnsider€d,
The Old Errylish Sheepd€ i;ie, one of the canine breede ,at risk of developing
pilomatricomas of benign behaviour.
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