Plenary sessions - Faculdade de Medicina da USP

Plenary sessions - Faculdade de Medicina da USP

SPSAS- Advances in Molecular Oncology:
Translating Molecular Biology into Cancer Treatment
Day
02/02/2013
Time
14:00 – 17:30
Check in, credentials, material distribution
07:30 – 08:45
Check in, credentials, material distribution
09:00 – 09:20
Opening Ceremony and Welcoming Remarks
Prof Dr José Otávio
Auler
Prof Dr Giovanni Guido
Cerri
Prof Dr Marco Antônio
Zago
Prof Dr José Eluf Neto
Prof Dr Roger Chammas
Prof Dra Maria A Nagai
Plenary sessions
FMUSP
Prof Dr Flavio Fava de
Moraes
Prof Dr Carlos Henrique
de Brito Cruz
Prof Dr Paulo Hoff
03/02/2013
Scientific Program
09:30 – 09:40
09:40 – 10:20
10:20 – 10:50
10:50 – 11:20
11:20 – 12:20
12:20 – 14:00
Director in Office of Medical School,
University of São Paulo (FMUSP)
Director of Medical School, University of
São Paulo (FMUSP)
Secretary of Health of the State of São Paulo
Pro-Chancellor of Research of the
University of São Paulo (USP)
Executive Director of the Laboratories of
Medical Investigation (LIMs)
Director of Medical School Foundation (FFM)
Scientific Director of Foundation for
Research Support of São Paulo (FAPESP)
Head of Clinical Oncology- Medical School,
University of São Paulo and ICESP Clinical
Diretor
Head of Basic Oncology- Medical School,
University of São Paulo (FMUSP)
Associate Professor, Medical School,
University of São Paulo (FMUSP)
Paulo Hoff – Welcome
Head of Clinical Oncology- Medical School, University of São
Paulo and ICESP Clinical Diretor, São Paulo, Brazil
Carlos Henrique de Brito Cruz
Diretor científico FAPESP, São Paulo, Brazil
Marco Antônio Zago – to be defined
Pro-Chancellor of Research of the University of São Paulo (USP), São
Paulo, Brazil
Coffee break
Opening conference
Molecular Imaging and the tumor microenvironment
Robert Gillies, Moffitt Cancer Center, Tampa, USA
Brunch
Chairs persons: José Eluf Neto
14:00 – 15:00
15:00 – 16:00
Epidemiology in the "omics" era: will the leaves hide the forest?
Núria Malats, CNIO, Madrid, Spain
Molecular Pathology in Breast Cancer as an example of
translational cancer research
Fernando Schmitt, IPATMUP, Porto, Portugal
16:00 – 16:30
Coffee break
16:30 – 17:30
Hepatocellular carcinoma – advances in the integration of
morphological and molecular aspects, towards a new classification
useful for clinical decisions
Park YN, Yonsei University College of Medicine, Seoul, Korea
17:30 – 18:30
Role of biomarkers in cancer detection and patient management
Michael J Duffy, School of Medicine & Medical Science, St
Vincents University Hospital, Dublin, Ireland
Welcome Cocktail
19:00 – 21:00
SPSAS- Advances in Molecular Oncology:
Translating Molecular Biology into Cancer Treatment
Day
Time
Room A
MC1 - Immunology for the non-immunologist
José Alexandre Barbuto, Biomedical Sciences Institute, University of
São Paulo, São Paulo, Brazil
MC2 - Principles of Clinical Research in Oncology
Room B
Rachel Simoes Pimenta Riechelmann, ICESP, São Paulo, Brazil
MC3 - 3D culture and mammary gland tumour engraftment as models
Room C
for studying the biology and therapeutics
Bruce Elliott, Queen’s University, Canada
Room A Chair persons: M Mitzi Brentani and Maria A Nagai
Session 1: Breast cancer
Mini-courses
8:00 – 8:45
09:00 – 09:50
Introduction to mammary gland biology and breast cancer
Paraic Kenny,Albert Einstein College of Medicine, Bronx, NY,USA
09:50 – 10:30
A novel Src/ezrin pathway in breast cancer metastasis: a potential
predictive marker
Bruce Elliott, Queen’s University, Kingston, Canada
10:30 – 11:00
Coffee break
11:00 – 11:30
Transcriptional profile as prognostic and predictive factor in breast
cancer
Maria A K Folgueira, Medical School, University of São Paulo, São
Paulo, Brazil
Initiation and Progression of breast cancer: Insights from gene
expression analysis
Dirce M Carraro, A C Camargo Hospital, São Paulo, Brazil
11:30 – 12:00
12:00 – 12:30
The role of tumor markers for diagnosis, prognosis and evaluation of
therapy response in breast cancer
Vivian Barak, Associate Professor in Oncology, Hebrew University,
Jerusalem, Israel
Room B Chairs persons: Luisa L Villa and Anna R. Giuliano
09:00 – 09:50 Epidemiology of anogenital cancers.
Anna R. Giuliano, H. Lee Moffitt Cancer & Center Research Institute,
Tampa, USA
Session 2: Anogenital tumors
09:00 – 12:30
Concurrent session - Molecular biology of cancer: an update
ICESP
04/02/2013
Scientific Program
09:50 – 10:30
Carcinogenic role of HPV in anogenital tumors
Enrique Boccardo, Biomedical Sciences Institute, University of São
Paulo, São Paulo, Brazil
10:30 – 11:00
Coffee break
11:00 – 11:30
Immune responses to HPV in normal tisssue and tumors of the uterine
cervix.
Ligia A. Pinto, National cancer Institute, Maryland, USA
HPV vaccination for anogenital cancer prevention
Luisa Lina Villa, Medical School, University of São Paulo, São Paulo,
Brazil-ICESP
11:30 – 12:00
12:00 – 12:30
Anogenital Cancer Treatment
Edmund Chada Baracat, Medical School, University of São Paulo, São
Paulo, Brazil
12:30 – 14:00 Brunch and Poster Session
SPSAS- Advances in Molecular Oncology:
Translating Molecular Biology into Cancer Treatment
Day
Scientific Program
Time
Session 3: Gastric cancer
Session 4: Hepatocellular and pancreatic tumors
Concurrent session - Molecular biology of cancer: an update
04/02/2013
ICESP
14:00 – 17:30
Room A Chairs persons: Ulysses Ribeiro, Jr and Ivan Cecconello
14:00 – 14:50
Molecular and immunohistochemical markers of gastric carcinoma
differentiation and progression.
Maria de Fátima Machado Henriques Carneiro – IPATIMUP, Porto,
Portugal
14:50 – 15:30
15:30 – 16:00
Familial gastric cancer: overview and guidelines for management.
Osmar K. Yagi – Clinics Hospital-Medical School, University of São
Paulo, São Paulo, Brazil
Gastric stump carcinoma. An experimental model for gastric
carcinogenesis?
Adriana Vaz Safatle Ribeiro – Clinical Hospital-Medical School,
University of São Paulo and ICESP, São Paulo, Brazil
16:00 – 16:30
Coffee break
16:30 – 17:00
Targeted therapy in gastric cancer.
Renata de Almeida Coudry – Cancer Institute São of Paulo State
ICESP
Room B Chairs persons: Venancio Alves and Young N Park
14:00 – 14:50
Morphological and Molecular characterization of the vascular features
of hepatocellular carcinoma from Dysplasia to Advanced Neoplasia
Annette Gouw, University Medical Center Groningen, Groningen,
Netherlands
14:50 – 15:30
Hypoxia and Hepatocarcinogenesis, emphasizing the putative role
of monocarboxylate transporters
Venancio Alves, Medical School, University of São Paulo/ICESP, São
Paulo, Brazil
A fibrous stromal component in hepatocellular carcinoma reveals a
cholangiocarcinoma-like gene expression trait and EMT.
Young N Park, Yonsei University College of Medicine Seodaemun,
Seoul, Korea.
15:30 – 16:00
16:00 – 16:30
Coffee break
16:30 – 17:00
Cholangiocarcinoma and variants
Evandro S Mello, Medical School, University of São Paulo, São
Paulo, Brazil
Room A
17:00 -17:30
Room B
The PrimerBank database of human and mouse primer pairs for gene
expression, detection and quantification
Athanasia Spandidos - Medical School, University of Athens, Greece
and Harvard Medical School, Boston, USA
To be defined
17:00 -17:30
Conference
17:30 – 18:30
Chair person: Maria A Nagai
Ras oncogene and human cancer
Demetrios Spandidos, Medical School, University of Crete, Creta, Greece
SPSAS- Advances in Molecular Oncology:
Translating Molecular Biology into Cancer Treatment
8:00 – 8:45
Time
Room A
Room B
MC1 - Immunology for the non-immunologist
José Alexandre Barbuto, Biomedical Sciences Institute, University of
São Paulo, São Paulo, Brazil
MC2 - Principles of Clinical Research in Oncology
Rachel Simoes Pimenta Riechelmann, ICESP, São Paulo, Brazil
MC3 - 3D culture and mammary gland tumour engraftment as
models for studying the biology and therapeutics
Bruce Elliott, Queen’s University, Canada
Room A Chairs persons: Gilberto de Castro and ….
Session 5: Head and Neck tumors
Room C
09:00 – 09:50
Predictive biomarkers analysis using FISH in lung cancer
MarileilaVarella-Garcia, School of Medicine, Division of Medical
Oncology, University of Colorado Denver, Denver, USA
09:50 – 10:30
miRNAs as gene regulators in thyroid cancer
Edna Teruko Kimura Biomedical Sciences Institute, University of
São Paulo, São Paulo, Brazil
10:30 – 11:00
Coffee break
11:00 – 11:30
Epigenetic silencing: its role in upper aerodigestive tract
carcinogenesis
André Lopes Carvalho, Cancer Hospital of Barretos, Barretos, Brazil
Molecular epidemiology of lung câncer
Carlos Gil Ferreira, National Institute of Cancer, Rio de Janeiro,
Brazil
Cancer-stromal interactions in upper aerodigestive cancers
Eloiza Helena Tajara da Silva, State of São Paulo University, São
José do Rio Preto, Brazil
11:30 – 12:00
12:00 – 12:30
Room B Chairs persons: Eduardo Rego and Robert Gallagher
Session 6: Hematopoietic tumors
Concurrent session - Molecular biology of cancer: an update 09:00 – 12:30
05/02/2013
ICESP
Mini-courses
Day
Scientific Program
09:00 – 09:50
ATRA-resistance in acute promyelocytic leukemia cells and its
functional correlations.
Robert Gallagher, Montefiore Medical Center, Albert Einstein
Cancer Center, USA
09:50 – 10:30
Mitochondrias as targets for acute leukemia treatment
Eduardo Rego, Medical School of Ribeirão Preto, University of São
Paulo, Ribeirão Preto, Brazil
10:30 – 11:00
Coffee break
11:00 – 11:30
Telomere length regulation in hematological malignancies
Rodrigo Calado, Medical School of Ribeirão Preto, University of São
Paulo, Ribeirão Preto, Brazil
Investigation of new targets in bone marrow cancers
Sara T. O. Saad, University of Campinas, Campinas, Brazil
Title to be defined
Gisele Colleoni , Federal University of São Paulo, São Paulo, Brazil
11:30 – 12:00
12:00 – 12:30
12:30 – 14:00
Brunch and Poster Session
SPSAS- Advances in Molecular Oncology:
Translating Molecular Biology into Cancer Treatment
Day
Scientific Program
Time
Session 7: Prostate cancer
14:00 – 14:50
Molecular basis of targeted therapy in metastatic renal cancer
Marc Garnick, Harvard Medical School, Boston, USA
14:50 – 15:30
Epigenetics in prostate cancer: biologic and clinical relevance.
Katia Moreira Leite, Medical School, University of São Paulo, São
Paulo, Brazil
15:30 – 16:00
Translational research in bladder cancer: from molecular
pathogenesis to useful tissue biomarkers.
Alberto Azoubel Antunes, Medical School, University of São Paulo,
São Paulo, Brazil
16:00 – 16:30
Coffee break
16:30 – 17:00
Tumor banks: the cornerstone of basic research in urology.
Sabrina Reis, Medical School, University of São Paulo, São Paulo,
Brazil
17:00 – 17:30
Molecular alterations and drug development for metastatic castrationresistant prostate cancer.
Marc Garnick, Harvard Medical School, Boston, USA
Room B Chairs persons: Suely K Marie and Gregory Riggins
Session 8: Central nervous system tumors
Concurrent session - - Molecular biology of cancer: an update
05/02/2013
ICESP
09:00 – 12:30
Room A Chairs persons: Miguel Srougi and Katia Moreira Leite
Conference
14:00 – 14:50
Translational cellular and animal models for glioblastoma therapeutic
management
Gregory Riggins, Ludwig Collaborative, Baltimore, USA
14:50 – 15:30
New and old approaches to search for anti-tumor targets of clinical
relevance
Mari Cleide Sogayar, NUCEL-Cell and Molecular Therapy Center,
University of São Paulo, São Paulo, Brazil
Immune panel access as a protection for the central nervous system
Regina Pekelmann Markus, Institute of Bioscience, University of São
Paulo, São Paulo, Brazil
15:30 – 16:00
16:00 – 16:30
Coffee break
16:30 – 17:00
The proteomic approach to search for new therapeutic targets
Jose Cesar Rosa, Medical School of Ribeirão Preto, University of
São Paulo, Ribeirão Preto, Brazil
17:00 – 17:30
Stem cell markers of medulloblastoma as therapeutic targets
Carlos Gilberto Carlotti, Medical School of Ribeirão Preto,
University of São Paulo, Ribeirão Preto, Brazil
17:30 – 18:30
Chair person- Roger Chammas
New mouse models for in vivo imaging of tumor metastasis:
application to gene discovery and drug response in melanoma
María S Soengas, Centro Nacional de Investigaciones Oncológicas,
Madrid, Spain
SPSAS- Advances in Molecular Oncology:
Translating Molecular Biology into Cancer Treatment
8:00 – 8:45
Time
Room A
Mini-courses
Day
Room B
Room C
09:00 – 9:50
9:00 – 12:30
Plenary session
MC1 - Immunology for the non-immunologist
José Alexandre Barbuto, Biomedical Sciences Institute, University of
São Paulo, São Paulo, Brazil
MC2 - Principles of Clinical Research in Oncology
Rachel Simoes Pimenta Riechelmann, ICESP, São Paulo, Brazil
MC3 - 3D culture and mammary gland tumour engraftment as
models for studying the biology and therapeutics
Bruce Elliott, Queen’s University, Canada
Chairs persons: Paulo H Saldiva and .....
Environment and cancer
Paulo H Saldiva, Medical School, University of São Paulo, São
Paulo, Brazil
Apoptosis: Extracellular Effects of the Tumor Suppressor Par-4
Vivek Rangnekar, Department of Radiation Medicine, University of
Kentucky, Lexington, USA
10:30 – 11:10
Novel Therapeutic Strategies for Recurrent Prostate Cancer
Anna Ferrari, NYU Cancer Institute, New York, USA
11:10 – 11:30
Coffee break
11:30 – 12:10
Abnormal O-glycosylation in cancer: from biology to clinical
applications
Eduardo Osinaga, Faculdad de Medicina, Universidad de la
Republica, Montevideo, Uruguay
12:10 – 12:50
Molecular pathways leading to pancreatic cancer
Francisco X. Real , CNIO, Madrid, Spain
12:50 – 14:00
Brunch
14:00 – 14:15
Oral presentation – selected papers
14:00 – 17:00
06/02/2013
ICESP
9:50 – 10:30
Conference
Scientific Program
14:15 – 14:30
14:30 – 14:45
14:45 - 15:00
15:00 – 15;15
15:15 – 15:45
Coffee break
15:45 – 16:00
16:00 – 16:15
16:15 – 16:30
16:30 - 16:45
16:45 – 17:00
17:00 – 18:00
Chair person: Roger Chammas
Tumor heterogeneity
Francisco X. Real , CNIO, Madrid, Spain
SPSAS- Advances in Molecular Oncology:
Translating Molecular Biology into Cancer Treatment
Day
Scientific Program
Time
Inherited tumors:
Plenary sessions
FMUSP
8:00 – 12:30
Chair persons: Lois M Mulligan and Sergio A Toledo
08:00 – 09:00
DICER1 mutations result in a surprising array of phenotypes
William D Foulkes, McGill University, Montreal, Canada
09:00 – 9:40
Ovarian cancer susceptibility genes
Patricia Tonin, McGill University, Montreal, Canada
9:40 – 10:20
Coffee break
10:20 – 10:40
Mechanisms of RET Receptor Dysfunction
Lois M Mulligan, Queen’s University, Kingston, Canada
10:40 – 11:20
Title to be defined
Sergio A Toledo, Medical School, University of São Paulo, São Paulo,
Brazil
11:20 – 12:00
Title to be defined
Patricia Dahia, San Antonio Cancer Institute, San Antônio, Texas,
USA
12:00 – 14:00
Brunch
Advanced Technologies and cancer therapy
14:00 – 18:30
Plenary sessions1
07/02/2013
Chair persons: Roger Chammas and Francisco Real
14:00 – 15:00
Advances in Nanomedicine and Nanotoxicology: Manipulation of
Nanomaterials for Diagnostic and Therapy
Valtencir Zucolotto Institute of Phisic, University of São Paulo, São
Carlos, Brazil
15:00 – 16:00
Targeted nanoparticles for non-invasive hyperthermia in malignant
disease
Steven A Curley, MD Anderson Cancer Center in Houston, Texas,
USA
16:00 – 16:30
Coffee break
16:30 – 17:30
Identification of subtype-specific breast cancer targets using 3D
culture models
Paraic Kenny, Albert Einstein College of Medicine, New York,USA
17:30 – 18:30
Reverse engineering multiple myeloma: putting numbers to faces
Ariosto Silva, Moffitt Cancer Center, Tampa, FL, USA
SPSAS- Advances in Molecular Oncology:
Translating Molecular Biology into Cancer Treatment
Day
Scientific Program
Time
Chair persons: Roger Chammas and Maria A Nagai
Plenary sessions
FMUSP
08:00 – 13:00
08:00 – 09:00
Standards for biomarkers and the role of the NCI on global cancer
research
Jorge Gomez, National Cancer Institute, Bethesda, USA
09:00 – 10:00
The EGFR/HER2 system as therapeutic targets for cancer
treatment
Michael J Duffy, School of Medicine & Medical Science, St
Vincents University Hospital, Dublin, Ireland
10:00 – 10:30
Coffee break
10:30 – 11:20
Biomarkers for prediction of Metastasis in Melanoma
Vivian Barak, Associate Professor in Oncology, Hebrew
University, Jerusalem, Israel
11:20 – 12:00
Publishing in Biomedical Sciences".
08/02/2013
Demetrios Spandidos, Medical School, University of Crete, Creta,
Greece
12:00 – 13:00
Closing Remarks (Roger Chammas; Jorge Gomez; Vivek
Rangnekar; Michael J Duffy) and Departure
Cancer Institute of São Paulo State
Supervised visit:
14:30 – 17:30
Medical School of the University of São Paulo
Center of Nuclear Medicine