full programme

Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Thursday: Symposium I / Session I
Symposium I: Immune cell regulation (in memoriam Walter Knapp)
Thursday,
Dec 2nd
Chair: Dietrich Kraft, Othmar Förster
L-1
TGF-β induces Foxp3 expression in CD4+CD25- naive T cells.
Wanjun CHEN
L-2
Development of regulatory CD4 T cells.
09:15 10:35
A. Y. RUDENSKY.
Session I: Overview of Austrian research in allergology and
immunology
Chair: Wilfried Ellmeier, Otto Scheiner
S-1
Studies of the IgE antigen receptor by the use of chimaeric IgEIgG1 “knock-in”-mice. Gertrude ACHATZ-STRAUSSBERGER, Nadja
ZABORSKY, Alexander KARNOWSKY, Marinus LAMERS and Gernot ACHATZ
S-2
Allergic disorders in elderly are underdiagnosed: First epidemiologic
study in elderly people. Noemi BAKOS, Isabella SCHÖLL, Krisztina SZALAI,
Eva UNTERSMAYR, Erika JENSEN-JAROLIM
S-3
Routine production of safety-optimized anti-allergic DNA vaccines
by forced ubiquitination. Richard WEISS, Sandra SCHEIBLHOFER,
Max GABLER, Roman BAUER, Tatjana STEPANOSKA, Arnulf HARTL, Josef
THALHAMER
S-4
Identification of a BTB/POZ domain-containing DNA binding
factor that modulates chromatin remodeling . Ivan BILIC, Christina
KÖSTERS, Arnulf HERTWECK, Romana MASCHEK and Wilfried ELLMEIER
S-5
Dendritic cell maturation by TLR and CD40-ligand is selectively
modulated by oxidized phospholipids. Stefan BLÜML, Stefanie
KIRCHBERGER, Valery N. BOCHKOV , Gerhard KRÖNKE, Karl M.
STUHLMEIER, Otto MAJDIC, Gerhard J. ZLABINGER, Walter KNAPP, Bernd
R. BINDER, Norbert LEITINGER, Johannes STÖCKL
S-6
Influence of gastro-intestinal digestion of the major peanut
allergen Ara h1 on allergen-specific response. Thomas EIWEGGER,
Neil RIGBY, Lucie MONDOULET, Maria KRAUTH, Alexandra BOEHM, Eleonora
DEHLINK, Clare MILLS, Jean M. WAL, Peter VALENT, Radvan URBANEK,
Zsolt SÉPFALUSI
S-7
Fetal skin contains Langerhans cell precursors. S. CHANGRODRIGUEZ, W. HOETZENECKER, C. SCHWÄRZLER, T. BIEDERMAN, S.
SAELAND, A. ELBE-BÜRGER
S-8
Pre-clinical examination of interleukin-12 secreting semi-mature
dendritic cells and application in a cancer vaccine trial. Sabine
K BREUER, Volker WITT, Wolfgang HOLTER, Helmut GADNER, Thomas
FELZMANN
S-9
Evidence for structurally oriented IgE recognition of a highly
allergenic domain on major timothy grass pollen allergen, Phl p 1.
Sabine FLICKER, Peter STEINBERGER, Marie-Theres KRAUTH, Tanja BALL,
Petra VERDINO, Peter VALENT and Rudolf VALENTA
11:00 12:30
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Thursday: Symposium II / Special Lecture / Session II
Thursday,
Dec 2nd
Symposium II: Genetic immune dysregulation syndromes
Chair: Hermann Wolf, Gerhard Zlabinger
13:30 14:50
16:20 17:00
L-3
Genetic basis of Familial Hemophagocytic Lymphohistiocytosis
syndromes. Geneviève DE SAINT BASILE
L-4
APECED- a single-gene defect causing a human autoimmune
disease. Pärt PETERSON
Special Lecture: Mouse models of skin autoimmunity and peripheral
tolerance. Steve KATZ
Chair: Georg Stingl
17:00 18:40
Session II: Overview of Austrian research in allergology and
immunology
Chair: Thomas Stulnig, Rudolf Valenta
S-10
Protection from IgE production and pathological alterations in the
lung by vaccination with a low-dose replicon-based DNA vaccine
encoding Phl p 5. Maximilian GABLER, Richard WEISS, Wolfgang W.
LEITNER, Kerstin KERN, Cornelia HAUSER-KRONBERGER, Beate ALINGER,
Rudolf VALENTA, Josef THALHAMER, Sandra SCHEIBLHOFER
S-11
The influence of membrane IgM on membrane IgD mediated signaling in
B-lymphocytes. Roland GEISBERGER, Stefan FEICHTNER and Gernot ACHATZ
S-12
CCL18 is selectively expressed in atopic dermatitis and mediates
skin homing of human memory T cells. Claudia GÜNTHER, Tamara
KOPP, Concha BELLO-FERNANDEZ, Julia KUND, Nicole CARBALLIDO-PERRIG,
Sonja HINTEREGGER, Sandra FASSL, Christoph SCHWÄRZLER, Günther
LAMETSCHWANDTNER, Georg STINGL, Tilo BIEDERMANN and José CARBALLIDO
S-13
Factor VIII (FVIII)-specific memory B cells but not memory T cells
are inhibited by supra-physiological concentrations of FVIII. Christina
HAUSL, Rafi U AHMAD, Maria SASGARY, Christopher B DOERING, Pete LOLLAR,
Günter RICHTER, Hans Peter SCHWARZ, Peter L TURECEK and Birgit M REIPERT
S-14
CD4+CD25+ Regulatory T cells are protective in Experimental antiGBM Glomerulonephritis in Mice. Kathrin HOCHEGGER, Dominik WOLF,
Anna M. WOLF, Eberhard GUNSILIUS, Alexander R. ROSENKRANZ
S-15
HLA-DRB1*01 is clearly associated with antigen-presentation of
the single immunodominant T cell epitope of Art v 1, the major
mugwort pollen allergen. Beatrice JAHN-SCHMID, Gottfried F. FISCHER,
Barbara BOHLE, Ingrid FAE, Gabriele GADERMAIER, Azra DEDIC, Fatima
FERREIRA and Christof EBNER
S-16
Immunization with a multiepitope peptide vaccine and coadministration of IL-12 prevent tumor growth in Her-2/neu
transgenic mice. J.JASINSKA , S.WAGNER , H.BREITENEDER ,
H.PEHAMBERGER , O.SCHEINER , C.C. ZIELINSKI , U. WIEDERMANN
S-17
Conditional activation of MAPK kinase 6 in immature dendritic
cells. Almut JÖRGL, Bernhard HÖCHER and Herbert STROBL
S-18
The balance between NF-kappaB and JNK/AP-1 activity controls
dendritic cell life and death. Ernst KRIEHUBER, Wolfgang BAUER, AnneSophie CHARBONNIER, Dorian WINTER, Georg STINGL and Dieter MAURER
S-19
Automated calculation of wheal-size of skin prick tests. Stefan
WÖHRL, Kornelia VIGL, Georg STINGL, Michael PRINZ
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Friday: Symposium III / Session III
Symposium III: 100 years autoimmunity by Karl Landsteiner
Chair: Hannes Stockinger, Beatrix Grubeck-Loebenstein
L-5
B cell signaling pathways underlying pathogenic autoimmunity.
Moncef ZOUALI
L-6
Innate response cytokines as therapeutic targets in inflammatory
arthritis? Iain B. McINNES
Session III: Overview of Austrian research in allergology and
immunology
Chair: Winfried Pickl, Ursula Wiedermann
S-20
Costimulation blockade inhibits allergic sensitization but not IgE
memory responses in a murine allergy model. Birgit LINHART, Sinda
BIGENZAHN, Arnulf HARTL, Josef THALHAMER, Rudolf VALENTA and
Thomas WEKERLE
S-21
Amplified serial TCR triggering in naïve and memory T cells by
dendritic cell-displayed peptide-MHC class II complexes. Paul
MERANER, Vaclav HOREJSI, Alois WÖLPL, Gottfried FISCHER, Georg
STINGL, Dieter MAURER
S-22
IL-4 induces CCL23 expression by human monocytes in a STAT6
dependent fashion. Maximilian WOISETSCHLÄGER, Hermann NOVAK,
Nathalie HARRER and Anke MÜLLER
S-23
Visualization of Lck activation in T cell receptor signalling using
GFP-reporters by Fluorescence Resonance Energy Transfer (FRET)
microscopy. Wolfgang PASTER, Christian PAAR, Max SONNLEITNER, Karel
DRBAL, Sabine SWOBODA, Alois SONNLEITNER and Hannes STOCKINGER
S-24
Structure of the food allergen Pru av 2. Yuliya DALL‘ANTONIA, Tea
PAVKOV, Heidemarie FUCHS, Heimo BREITENEDER, Walter KELLER
S-25
The antirheumatic drug leflunomide blocks T cell adhesion to
ICAM-1 and fibronectin independently of de novo pyrimidine
synthesis. Marko POGLITSCH, Maximilian ZEYDA, René GEYEREGGER,
Walter W. HÖRL, Thomas M. STULNIG and Marcus D. SÄEMANN
S-26
C-type Lectin independent interaction of opsonized HIV with
monocyte-derived dendritic cells. Monika PRUENSTER, Doris
WILFINGSEDER, Zoltan BANKI, Christoph G. AMMANN, Martina MEYER,
Manfred P. DIERICH and Heribert STOIBER
S-27
Tryptase-mediated termination of allergen-induced mast cell
degranulation by cleavage of IgE. I. RAUTER, M.T. KRAUTH, S.
FLICKER, H. SEMPER, N. BALIC, S. SPITZAUER, J. HUSS-MARP, U.
DARSOW, K. BROCKOW, H. BEHRENDT, J. RING, P. VALENT, R. VALENTA
S-28
Regulation of cell migration by the Mannose 6-Phosphate/Insulinlike growth factor 2 receptor: The molecular mechanism and
physiological relevance. Vladimir LEKSA, Herbert SCHILLER, Katarina
SLEZAKOVA, Johannes BREUSS, Bernd BINDER, Hannes STOCKINGER
Friday,
Dec 3rd
09:00 10:20
sponsored
by Szabo
Scandic
11:00 12:30
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Friday: Symposium IV / Session IV
Friday,
Dec 3rd
Symposium IV: Molecular allergology
Chair: Barbara Bohle, Karin Hoffmann-Sommergruber
13:30 14:50
16:20 18:00
L-7
T regulatory cells in allergic and healthy immune response.
Mübeccel AKDIS
L-8
Molecular basis of IgE cross-reactions. Ronald VAN REE
Session IV: Overview of Austrian research in allergology and
immunology
Chair: Fátima Ferreira-Briza, Nikolaus Romani
ÖGAI
General
Assembly
18:00 19:30
S-29
Dimerization of the major birch pollen allergen Bet v 1 is a
precondition for crosslinking murine IgE. Isabella SCHÖLL, Narayana
KALKURA, Yuliya SHEDZIANKOVA, Alexander BERGMANN, Petra VERDINO,
Brigitte HANTUSCH, George BOLTZ-NITULESCU, Christian BETZEL, Karsten
DIERKS, Walter KELLER, and Erika JENSEN-JAROLIM
S-30
Identification and characterization of pDC-like cells in normal mouse
skin and melanomas treatedwith Imiquimod. Francesca PALAMARA, Simone
MEINDL, Martin HOLCMANN, Petra LÜHRS, Georg STINGL and Maria SIBILIA
S-31
Thymocytes of the nonobese mouse model of autoimmune diabetes are
resitant to Glucocorticoid-induced Apoptosis in vivo but not in vitro.
Ilona STEC, Günther BÖCK, Hermann DIETRICH, Georg WICK, Jan WIEGERS
S-32
B7-DC (PD-L2) inhibits activation of human T cells. Katharina
PFISTERSHAMMER, Christoph KLAUSER, Winfried F. PICKL, Johannes
STOECKL, Gerhard ZLABINGER, Otto MAJDIC, Peter STEINBERGER
S-33
Can Langerhans cells crosspresent exogenous antigen on MHCclass I molecules?. Patrizia STOITZNER, N. ROMANI
S-34
A functional genetic screen reveals GATA-1 as inhibitor of vitamin
D3 induced differentiation of U937 cells. S. TASCHNER, M. KUMERZ,
B. PLATZER, L. HEINZ and H. STROBL
S-35
Role of Tec family kinases in macrophages. Bernd UNGER, Martin
MELCHER, Iiro A RAJANTIE, Niklas EKMAN, Kari ALITALO and Wilfried
ELLMEIER
S-36
Early activation of sphingosine kinase in mast cells and recruitment
to Fc(epsilon)RI is mediated by its interaction with Lyn kinase.
Nicole URTZ, Ana OLIVERA, Elisa BOFILL-CARDONA, Robert CSONGA,
Andreas BILLICH, Diana MECHTCHERIAKOVA, Frederic BORNANCIN, Max
WOISETSCHLÄGER, Juan RIVERA, and Thomas BAUMRUKER
S-37
Tamm-Horsfall Glycoprotein (THP) activates professional antigen
presenting cells and THP-specific humoral immunity via a
Toll-like receptor 4-mechanism. Thomas WEICHHART, Marcus D.
SÄEMANN, Maximilian ZEYDA, Günther STAFFLER, Michael SCHUNN, Karl
M. STUHLMEIER, Yuri SOBANOV, Thomas M. STULNIG, Uwe VON AHSEN,
Walter H. HÖRL, Alexander VON GABAIN, Gerhard J. ZLABINGER
S-38
Simultaneous TGF-beta, IL-10 and Foxp3 expression in CD4+ T
cells depends on the conformation of the antigen in a model of
mucosal tolerance induction. Birgit WINKLER, Karin HUFNAGL, Andreas
SPITTLER, Susanne VRTALA, Rudolf VALENTA, Ursula WIEDERMANN
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Wiener Allergiegespräche
Wiener Allergiegespräche
Eröffnung
Saturday,
Dec 4th
08:55
Vorsitz: E. Jensen-Jarolim
L-9
Allergien im Kindesalter. Zsolt SZEPFALUSI
L-10
Asthmatherapie im Kindesalter. T. NÜSSLEIN
09:00 10:30
Zur spezifischen Immuntherapie mit Allergoiden - wo stehen wir?
P. SCHMID-GRENDELMEIER
Vorsitz: W. Hemmer
L-11
Nahrungsmittelallergien. B. BALLMER-WEBER
L-12
Antacida und Nahrungsmittelallergien. E. UNTERSMAYR
11:00 12:30
Neurodermitis. M. BINDER
Vorsitz: R. Jarisch
L-13
Allergie und Schock. R. PUMPHREY
Fälle aus der Praxis (Case reports)
13:30 14:00
14:00 15:00
Anaphylaxis to Resonance Contrast Media due to Type I allergy
against meglumine. C. EGGER, N. REIDER
Allergie gegen Copaone. C. EBNER
Allergie gegen Mais. K. TÖRÖK
Kartoffelallergie. W. HEMMER
Anaphylaktische Reaktion auf Broccoli. B. ZAHEL
L-14
Allergiequiz. B. KRÄNKE
Schlussworte
15:00
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Poster Workshops I - IV: Thursday
Room 1
PIAFFE
Poster Workshop I: Allergy diagnostics
Chair: Margarete Focke-Tejkl, Felix Wantke
Thursday,
Dec 2nd
14:50 16:20
P-1
The profile of IgE- and IgA-reactive wheat antigens varies in
different wheat breeds and is differentially regulated during
seed maturation. Claudia CONSTANTIN, Wolf D. HUBER, Gerhard
GRANDITSCH, Santiago QUIRCE, Alisher TOURAEV, Rudolf VALENTA
P-2
Recombinant Production of Single-Chain Fv Antibody Fragments
Specific for Arabinose Residues of theArt v 1 Glycan. Petra
GRUBER, Azra DEDIC, Gabriele GADERMAIER, Stefan WAGNER, Heimo
BREITENEDER, Renaud LEONARD, Friedrich ALTMANN, Fatima FERREIRA
P-3
Identification by Immunoblot of Venom Glycoproteins Displaying
IgE-binding N-glycans as Cross-reactive Allergens in Honeybee
and Yellow Jacket Venom. Wolfgang HEMMER, Margarete FOCKE, Daniel
KOLARICH, Ingrid WEISSMANN, Manfred GÖTZ, Reinhart JARISCH
P-4
Flow cytometry based analysis of bronchoalveolar lavage in a
mouse model of allergy. Kerstin KERN, Cornelia HAUSER-KRONBERGER,
Beate ALINGER, Maximilian GABLER, Sandra SCHEIBLHOFER, Josef
THALHAMER, Richard WEISS
P-5
Development of a dipstick assay for the determination of traces of
peanut and hazelnut proteins in food employing chicken egg yolk
antibodies (IgY). I. LEITZENBERGER, E. DRS, S. BAUMGARTNER, R.
KRSKA, M. BREMER, A. KEMMERS-VONCKEN, N. SMITS, W. HAASNOOT, J.
BANKS, P. REECE, C. DANKS, V. TOMKIES, U. IMMER, K. SCHMITT
P-6
Fine specificities of patients’ IgE binding to the major cat allergen
Fel d 1 revealed bytwo-dimensional immunoblotting. Alexander D.
LINDEMEIER, Ines SWOBODA, Renate REININGER, Margarete FOCKE,
Hans GRONLUND, Marianne van HAGE-HAMSTEN, Helmut RUMPOLD,
Rudolf VALENTA and Susanne SPITZAUER
P-7
A highly sensitive assay for the detection of immune complexes
consisting of major birch pollen allergen Bet v 1 and Bet v
1-specific human IgE. J. REISINGER, B. BOHLE, R. VALENTA, V.
NIEDERBERGER
P-8
Microarray-based improvement of diagnosis forlatex allergy. Stefan
WAGNER, Christian HARWANEGG, Birgit WAGNER, Christine HAFNER,
Adriano MARI, Christof EBNER, Reinhard HILLER, Otto SCHEINER, Heimo
BREITENEDER
P-9
Variability of IgE reactivity profiles to house dust mite allergens
in European populations revealed with purified natural and
recombinant allergens. Margit WEGHOFER, Wayne R. THOMAS,
Marianne VAN HAGE-HAMSTEN, Adriano MARI, Gabrielle PAULI, Friedrich
A. HORAK, Rudolf VALENTA, Susanne VRTALA
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Poster Workshops I - IV: Thursday
Poster Workshop II: Molecular Allergology
Room 2
LEVADE
Chair: Gernot Achatz, Susanna Vrtala
P-10
Stability of Act c 2, a thaumatin-like protein and a major allergen
of kiwi to heating and gastrointestinal digestion. M. BUBLIN, E.N.C.
MILLS, F. HUSBEND, N.M. RIGBY, K. HOFFMANN-SOMMERGRUBER, C.
RADAUER, O. SCHEINER, H. BREITENEDER
P-11
Isoforms of Art v 1, the major mugwort pollen allergen. Azra DEDIC,
Gabriele GADERMAIER, Roman BAUER, Lothar VOGEL, Josef THALHAMER,
Christof EBNER, Stefan VIETHS, Fatima FERREIRA
P-12
Art v 1, the Major Mugwort Allergen, Cross-reacts with Proteins
Originating from Compositae and Grass Pollen. Matthias EGGER,
Nicole WOPFNER, Martin HIMLY, Azra DEDIC, Roman BAUER, Adriano MARI,
Ronald VAN REE, Arnulf HARTL, Josef THALHAMER, Fatima FERREIRA
P-13
Physico-chemical properties of Pru av 2, an important allergen
from cherry. Heidemarie FUCHS, Merima BUBLIN, Clare MILLS, Otto
SCHEINER, Heimo BREITENEDER
P-14
Biochemical and biophysical characterisation of natural and
recombinant major allergens of birch, grass and olive pollen. G
GADERMAIER , M WALLNER , M SUSANI , R MONSALVE , H FIEBIG , W.M.
BECKER , M VILLALBA , R van REE , F FERREIRA and the CREATE CONSORTIUM
P-15
Small-angle x-ray scattering for determination of molecular size,
shape, and aggregation state of natural and recombinant allergens
in solution. Martin HIMLY, Gerhard FRITZ, Otto GLATTER, Ronald VAN
REE, Fátima FERREIRA and the CREATE CONSORTIUM
P-16
Towards the structure of thaumatin-like kiwi food allergen. Marija
JANKOVIC, Tea PAVKOV, Merima BUBLIN, Heimo BREITENEDER, Walter
KELLER
P-17
Different apple cultivars showing a markedly different content
in Mal d1. G. MARZBAN, R. DEY, Y. MA, R. ASERO, A. MARTINELLI, M.
ZACCHARINI, M. LAIMER
P-18
Cloning, expression and purification of biotinylated Bet v 1a
designed for enhanced specific uptake by human B cells. Sonja
MUTSCHLECHNER, Barbara BOHLE, Beatrice JAHN-SCHMID, Christof
EBNER, Martin HIMLY, Fatima FERREIRA
P-19
Different IgE binding activity of Mal d 1 isoforms, the major apple
allergen. Christina OBERHUBER, Yan MA, Irene LEITZENBERGER, Barbara
BOHLE, Christian RADAUER, Helene PÜHRINGER, Margit LAIMER, Otto
SCHEINER, Karin HOFFMANN-SOMMERGRUBER
P-20
Characterization and purification of a vacuolar serine protease of
Cladosporium herbarum. Verena PÖLL, Thomas HAWRANEK, Horng-Der SHEN,
Michael BREITENBACH, Birgit SIMON-NOBBE
P-21
Identification of a dog allergen which cross-reacts with the major
cat allergen, Fel d 1. Renate REININGER, Eva Maria VARGA, Nadja
BALIC, Alexander D. LINDEMEIER, Ines SWOBODA, Hans GRÖNLUND,
Marianne VAN HAGE-HAMSTEN, Helmut RUMPOLD, Rudolf VALENTA,
Susanne SPITZAUER
Thursday,
Dec 2nd
14:50 16:20
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Poster Workshops I - IV: Thursday
Room 2
LEVADE
P-22
Cloning of the Major Cedar Pollen Allergens Jun a 1 and Cry j 1
and Expression of Recombinant Proteins. Georg SCHMIDT and Fatima
FERREIRA
Thursday,
Dec 2nd
P-23
Occupational allergy to ribosome-inactivating proteins (RIPs) in
researchers. Krisztina SZALAI, Isabella SCHÖLL, Angelika B RIEMER,
Elisabeth FÖRSTER-WALDL, Georg BOLTZ-NICULESCU, Letizia POLITO,
Andrea BOLOGNESI, Fiorenzo STIRPE, Erika JENSEN-JAROLIM
P-24
Polygalacturonases as grass pollen-specific marker allergens
and potential elicitors of bronchial asthma. Ines SWOBODA, Monika
GROTE, Petra VERDINO, Walter KELLER, Mohan B. SINGH, Nicole DE
WEERD, Wolfgang SPERR, Peter VALENT, Nadja BALIC, Rudolf REICHELT,
Roland SUCK, Helmut FIEBIG, Rudolf VALENTA and Susanne SPITZAUER
P-25
Structural characterization of natural and recombinant
preparations of house dust mite allergens. Michael WALLNER, Gabriele
GADERMAIER, Lisa D. VAILES, Martin CHAPMAN, Ronald VAN REE, Fátima
FERREIRA and the CREATE CONSORTIUM
P-26
Immunological characterization of a novel house dust mite
(Dermatophagoides pteronyssinus) allergen. Margit WEGHOFER,
Maria-Theresa KRAUTH, Peter VALENT, Rudolf VALENTA, Susanne VRTALA
14:50 16:20
Room 3
COURBETTE
Poster Workshop III: Dendritic cells
Chair: Johannes Stöckl, Christine Heufler-Tiefenthaler
14:50 16:20
P-27
Molecular analysis of epithelial Langerhans cell differentiation.
Leonhard HEINZ, Bernhard HÖCHER and Herbert STROBL
P-28
Migration of Langerhans cell precursors intotape-stripped
epidermis. Sandra HOLZMANN, Christoph H. TRIPP, Franz KOCH, Patrizia
STOITZNER, Nikolaus ROMANI
P-29
The maturation and migration capacity of antigen presenting cells
of the skin remains unchanged after treatment with pimecrolimus.
W. HOETZENECKER, J.G. MEINGASSNER, G. STINGL, A. STUETZ, A. ELBEBÜRGER
P-30
Phases in a dendritic cell´s life determine T cell activation and
polarization. S. KIRCHBERGER, O. MAJDIC, K. PFISTERSHAMMER, P.
STEINBERGER, G. ZLABINGER, W. KNAPP, J. STÖCKL
P-31
Leflunomide potently interferes with dendritic cell function.
Bernhard KIRSCH, Maximilian ZEYDA, Karl STUHLMEIER, Johannes
GRISAR, Josef SMOLEN, Thomas M. STULNIG, Gerhard J. ZLABINGER,
Bruno WATSCHINGER, Walter H. HÖRL, Marcus D. SÄEMANN
P-32
Identification of a Transcription Factor that negatively regulates
dendritic cell differentiation and maturation. Christina KÖSTERS,
Bernd UNGER, Stefanie KIRCHBERGER, Johannes STÖCKL, Martin
SCHREIBER and Wilfried ELLMEIER
P-33
Lectin-like Receptors of the human NK Gene complex expressed
on dendritic cells. Hormas GHADIALLY, Susanne SATTLER, Irene MICHL,
Manuela KROPIK, Frank KALTHOFF and Erhard HOFER
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Poster Workshops I - IV: Thursday
P-34
The neonatal and adult murine dermis harbours cells with in vitro
clonogenic potential: characterization and enrichment strategies.
Simone MEINDL and Adelheid ELBE-BÜRGER
Room 3
COURBETTE
P-35
RelB regulates human dendritic cell subset development by promoting
Monocyte intermediates. PLATZER B., JORGL A., TASCHNER S., HOCHER B.
and STROBL H.
Thursday,
Dec 2nd
P-36
Profiling changes in protein expression during polarized
dendritic cell differentiation with immunoproteomics. Elisabeth
TRAXLER, Stefan BLÜML, Hannes ZWICKL, Stefanie KIRCHBERGER, Nina
GUNDACKER, Otto MAJDIC, Johannes STÖCKL and Christopher GERNER
14:50 16:20
P-37
A NF-kappaB independent block of dendritic cell activation and
function mediated bypolyunsaturated fatty acids. Maximilian ZEYDA,
Marcus D. SÄEMANN, Karl M. STUHLMEIER, Gerhard J. ZLABINGER, Werner
WALDHÄUSL and Thomas STULNIG
Poster Workshop IV: T cells
Chair: Herbert Strobl, Achim Schneeberger
P-38
Costimulatory effects of TNF-RII on TCR stimulation are IL-2
dependent whereas inhibitory effects are not. R.M. ASPALTER, M.M.
EIBL, H.M. WOLF
P-39
Immunosomes: Towards in vivo application of a novel T cell
stimulation tool box. Sophia V. DERDAK, Hans-Joerg KUENG, Victoria
LEB, Edith BIELEK, Otto MAJDIC, Walter KNAPP, Brian SEED and Winfried F.
PICKL
P-40
Calcineurin inbibitors and corticosteroids interfere with formation
of the immunological synapse. René GEYEREGGER, M D SÄEMANN, M.
ZEYDA, W. WALDÄUSL and T. M. STULNIG
P-41
Analysis of the molecular mechanisms of T cell inhibition
underlying CD 147 triggering. Christa HOLZHAUSER, Birgit RICHTER,
Vaclav HOREJSI, Hannes STOCKINGER
P-42
Naive T cells show different reorganization dynamics of lipid rafts
after TCR/CD3 triggering visible by single molecule microscopy.
Karel DRBAL, Manuel MÖRTELMAIER, Ivan GOMEZ, Gerhard SCHÜTZ,
Hannes STOCKINGER
P-43
Age-related loss of naïve T cells and dysregulation of T cell/B
cell interactions in human lymph nodes. Lutfan LAZUARDI, Brigitte
JENEWEIN, Anna Maria WOLF, Gerald PFISTER, Alexandar TZANKOV &
Beatrix GRUBECK-LOEBENSTEIN
P-44
Influencing the allergen-specific immune response at the level
of antigen presentation:ANERGOSOMES for antigen-specific
anergisation. Victoria LEB, Sophia V. DERDAK, Hans-Joerg KUENG,
Barbara BOHLE, Beatrice JAHN-SCHMID, Gottfried F. FISCHER, Otto
MAJDIC, Walter KNAPP, Brian SEED and Winfried F. PICKL
Room 4
CAPRIOLE
14:50 16:20
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Poster Workshops I - IV: Thursday
Room 4
CAPRIOLE
P-45
Thursday,
Dec 2nd
CD63, an activation-linked T cell costimulatory element. Katharina
PFISTERSHAMMER, Otto MAJDIC, Johannes STOECKL, Gerhard
ZLABINGER, Stefanie KIRCHBERGER, Peter STEINBERGER and Walter
KNAPP
P-46
14:50 16:20
The influence of thymectomy in early childhood on the immune
function later in life. Martina PRELOG, Michael KELLER, Ulrich
SCHWEIGMANN, Beatrix GRUBECK-LOEBENSTEIN, Ralf GEIGER
P-47
Selective inhibition of T cell subsets via CD147. Birgit RICHTER,
Andreas SZEKERES, Gerhard ZLABINGER, Vaclav HOREJSI and Hannes
STOCKINGER
P-48
4-Amino tetrahydrobiopterin attenuates dendritic cell induced T
cell priming independently from inducible nitric oxide synthase.
Guntram THOENI, Patrizia STOITZNER, Gerald BRANDACHER, Nikolaus
ROMANI, Christine HEUFLER, Gabriele WERNER-FELMAYER and Ernst R.
WERNER
P-49
The role of Tec and Itk kinases in CD8+ T cells. Benjamin VIGL,
Nicoleb BOUCHERON, Petra LUHRS, Achim SCHNEEBERGER, Wilfried
ELLMEIER
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Poster Workshops V - VIII: Friday
Poster Workshop V: Allergy therapy
Room 1
PIAFFE
Chair: Thomas Baumruker, Heimo Breiteneder
P-50
Vaccination character of Dermatophagoides pteronys-sinus
allergoid injection immunotherapy revealed with recombinant
allergens and allergen fragments. Kuan-Wei CHEN, Margit WEGHOFER,
Susanne SEIBERLER, Wayne THOMAS, Friedrich HORAK, Petra
ZIEGLMAYER, Alexander KAVINA, Huub KLEINJANS, Rudolf VALENTA,
Susanne VRTALA
P-51
Generation and evaluation of hypoallergenic derivatives of the
major mite allergen Der p 2,for specific immunotherapy. KuanWei CHEN, Gudrun PITTNER, Marija JANKOVIC, Walter KELLER, Rudolf
VALENTA, Susanne VRTALA
P-52
Hydrocortisone enhances total IgE production by cord blood
mononuclear cells from preterm and term deliveries in vitro.
Eleonora DEHLINK, Hedwig DUFFING, Peter CIZNAR, Marianne
GERSTMAYR, Marianne GERSTMAYR, Elke KAMPL, Christine LOIBICHLER,
Radvan URBANEK and Zsolt SZÉPFALUSI
P-53
Preventive allergy vaccination with non-anaphylactic surfaceexposed peptides of the major birch pollen allergen, Bet v 1.
Margarete FOCKE, Birgit LINHART, Arnulf HARTL, Josef THALHAMER,
Dietrich KRAFT and Rudolf VALENTA
P-54
Effects of the Allergen-S-Layer Fusion Protein, rSbsC-Bet v1,
on Human Dendritic Cells (DC). Marianne GERSTMAYR, Andreas
BREITWIESER, Bettina ZWOELFER, Astrid RADAKOVICS, Beatrice JAHNSCHMID, Margit SARA, Christof EBNER, Barbara BOHLE
P-55
A model system to dissect allergen-induced basophil activation. Anna
GIERAS, Margit FOCKE, Arnulf HARTL, Josef THALHAMER and Rudolf VALENTA
P-56
Production of recombinant human interleukin 10 in a bacterial
expression system for immunomodulation of type I allergy. Ulrike
GRIESMEIER, Birgit WAGNER, Marianne GERSTMAYR, Barbara BOHLE, Otto
SCHEINER, Heimo BREITENEDER
P-57
Targeting membranous cells: A novel approach for oral allergen
immunotherapy. Franziska ROTH-WALTER, Isabella SCHÖLL, Eva
UNTERSMAYR, David BRAYDEN, George BOLTZ-NITULESCU, Otto
SCHEINER, Franz GABOR, Erika JENSEN-JAROLIM
P-58
Escherichia coli expression of a single chain variable fragment
(ScFv) with specificity for human IgE. Christian LUPINEK, Sylvia
LAFFER, Tanja BALL, Hakan ENGLUND, Rudolf VALENTA
P-59
Modulation Of The IgE Response By Blocking Membrane-IgE.
Daniela INFÜHR, Eva MURAUER, Gernot ACHATZ
P-60
Vaccination with genetically engineered allergens prevents
progression of allergic disease. V. NIEDERBERGER, F. HORAK, S.
VRTALA, S. SPITZAUER, M.-T. KRAUTH, P. VALENT, J. REISINGER, M. VAN
HAGE-HAMSTEN, G. PAULI, O. CROMWELL, R. VALENTA
Friday,
Dec 3rd
14:50 16:20
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Poster Workshops V - VIII: Friday
Room 1
PIAFFE
Friday,
Dec 3rd
P-61
DNA vaccination with the allergen mimotope F1 of Phl p 5 induces
a Th1-biased immune response against the native allergen. Martina
PRÖLL, Brigitte HANTUSCH, Theresa THALHAMER, Tatjana STEPANOSKA,
Angelika RIEMER, Erika JENSEN-JAROLIM, Josef THALHAMER, Arnulf HARTL
P-62
Vaccine-induced allergen-specific IgG antibodies in nasal
secretions are associated with reduced nasal allergen sensitivity.
Jürgen REISINGER, Friedrich HORAK, Oliver CROMWELL, Gabrielle PAULI,
Marianne VAN HAGE-HAMSTEN, Rudolf VALENTA, Verena NIEDERBERGER
P-63
Characterization of DNA vaccines encoding genes created by family
gene shuffling of Bet v1 homologues. Theresa THALHAMER, Martina
PRÖLL, Tatjana STEPANOSKA, Michael WALLNER, Angelika STÖCKLINGER,
Peter HAMMERL, Fatima FERREIRA, Josef THALHAMER, Arnulf HARTL
P-64
Oligomerization of hypoallergenic fragments of the major birch
pollen allergen, Bet v 1, increases immunogenicity. Susanne VRTALA,
Monika FOHR, Birgit LINHART, Rudolf VALENTA
P-65
Production of a fusion between the B subunit of the cholera
toxin of Vibrio Cholerae and the major birch pollen allergen Bet
v 1 as immunomodulator. Birgit WAGNER, Merima BUBLIN, Christian
RADAUER, Stefan WAGNER, Dorothee ALLWARDT, Otto SCHEINER, Heimo
BREITENEDER
P-66
A “tail-to-head” - derivative from timothy grass pollen profilin
for allergy vaccination. Kerstin WESTRITSCHNIG, Margit FOCKE, Tanja
BALL, Adriano MARI, Arnulf HARTL, Josef THALHAMER, Alexandra BÖHM,
Peter VALENT and Rudolf VALENTA
P-67
Use of an Allergen chimer for mucosal tolerance induction in
polysensitized mice. Carmen WILD, Karin HUFNAGL, Michael WALLNER,
Heidemarie FUCHS, Karin HOFFMANN-SOMMERGRUBER, Heimo
BREITENEDER, Fatima FERREIRA and Ursula WIEDERMANN
14:50 16:20
Room 2
LEVADE
14:50 16:20
Poster Workshop VI: Innate Immunity
Chair: Heribert Stoiber, Adelheid Elbe-Bürger
P-68
Defence against complement attack:a general mechanism for
enveloped viruses? Christoph G. AMMANN, Monika PRÜNSTER, Brigitte
MÜLLAUER, Zoltan BÁNKI, Manfred P. DIERICH and Heribert STOIBER
P-69
Complement Dependent Trapping of Infectious HIV on Human
Lymphoid Tissues. Zoltán BÁNKI, Laco KACANI, Peter RUSERT, Monika
PRÜNSTER, Doris WILFLINGSEDER, Barbara FALKENSAMMER, Hans-Jürgen
STELBRINK, Jan van LUNZEN, Alexandra TRKOLA, Manfred P. DIERICH,
Heribert STOIBER
P-70
Oxidative stress-induced necrosis is causally related to PARP
activation and energy depletion in HUVEC cells. Adam CSORDAS,
Georg WICK, David BERNHARD
P-71
Help or handicap - The effect of C3d fused to genetic vaccines
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Poster Workshops V - VIII: Friday
depends on the nature of the antigen. Maximilian GABLER, Sandra
SCHEIBLHOFER, Elke S. BERGMANN-LEITNER, Richard WEISS, Thomas
JACOBS, Elizabeth H. DUNCAN, Wolfgang W. LEITNER, Defeng CHEN,
Evelina ANGOV, Farhat KHAN, Jackie L. WILLIAMS, David B. WINTER, Josef
THALHAMER, Jeffrey LYON
P-72
Involvement of protein kinase C in phagocytosis of human retinal
pigment epithelial cells and induction of matrix metalloproteinase
secretion. Gertrud HAAS, Josef TROGER, Florian ÜBERALL, Wolfgang
GÖTTINGER, Hartwig P. HUEMER, Eveline U. IRSCHICK
P-73
Role of Perforin, Granzyme A and Granzyme B in PhagocytosisInduced Cell Death of Human Polymorphonuclear Neutrophils.
Kathrin HOCHEGGER, Philipp ELLER, Gerhard J. ZLABINGER, Alexander R.
ROSENKRANZ
P-74
Long-term Exposure to Bacterial Pathogen-Associated Molecular
Patterns (PAMPs): Role of Toll-like Receptors (TLR)2, 4 and
Transcription Factor NFkB. Reinhard B. RAGGAM, Barbara KLEINHAPPL,
Bernd HEINRICH, Andrea ZAUNER, Sonja BARTH and Egon MARTH
P-75
HIV-1-induced migration of monocyte-derived dendritic cells is
associated with differential activation of MAPK pathways. Doris
WILFLINGSEDER, Brigitte MÜLLAUER, Herbert SCHRAMEK, Zoltan BANKI,
Monika PRUENSTER, Manfred P. DIERICH and Heribert STOIBER
P-76
Comparison of replicase-based DNA vaccines using different
alphaviral replicons. Thomas ZÖGG, Roman BAUER, Maximilian GABLER,
Sandra SCHEIBLHOFER, Wolfgang W. LEITNER, Josef THALHAMER, Richard
WEISS
Poster Workshop VII: Mechanism of allergic diseases
Chair: Beatrix Jahn-Schmidt, Zsolt Szépfalusi
P-77
Serum IgE-autoantibodies of atopic dermatitis patients target
keratinocytes in the skin. Sabine ALTRICHTER, Ernst KRIEHUBER,
Sebastian GRAFFI, Rudolf VALENTA, Tamara KOPP, Georg STINGL
P-78
Outstanding Affinity of IgE: Comparison of Antibody Affinities
towards Phl p 5a and Bet v 1 Using Surface Plasmon Resonance.
Brigitte HANTUSCH, Isabella SCHÖLL, Christian HARWANEGG, Sigurd
KRIEGER, Wolf-Meinhard BECKER, Susanne SPITZAUER, George BOLTZNITEULESCU, Erika JENSEN-JAROLIM
P-79
IL-4 and IL-13 induced Eotaxin-3 expression is inhibited by
SOCS-1 and SOCS-3. Daniel HEBENSTREIT, Petra LUFT, Angela
SCHMIEDLECHNER, Albert DUSCHL and Jutta HOREJS-HOECK
P-80
Intranasal treatment with poly-peptides prevents allergic polysensitization and lung inflammation in mice. Karin HUFNAGL, Birgit
WINKLER, Margit FOCKE, Rudolf VALENTA, Otto SCHEINER, Ursula WIEDERMANN
P-81
Construction of a chimeric mIgE antigen receptor. Stefan B. LENZ,
Gernot ACHATZ
P-82
Allergen Specific IgG and IgA Memory B Cells In Atopic And NonAtopic Individuals. E Luger, G Achatz, A Radbruch, C Berek
Room 2
LEVADE
Friday,
Dec 3rd
14:50 16:20
Room 3
COURBETTE
14:50 16:20
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Poster Workshops V - VIII: Friday
Room 3
COURBETTE
Friday,
Dec 3rd
14:50 16:20
Room 4
CAPRIOLE
14:50 16:20
P-83
Allergen-specific IgE VH genes show a broad usage of VH families
and contain somatic mutations. Katharina MARTH, Margarete FOCKETEJKL and Rudolf VALENTA
P-84
Hom s 2, an IgE-reactive autoantigen induces Th1-activation and
IFN-gamma-mediated disintegration of respiratory epithelial cell
layers. Irene MITTERMANN, Renate REININGER, Karl J. AICHBERGER,
Jürgen REISINGER, Verena NIEDERBERGER, Barbara BOHLE, Peter
VALENT, Ernst KÜCHLER and Rudolf VALENTA
P-85
The cradle of IgE autoreactivity lies in early infancy. Nadine
MOTHES, Tobias HAGEMANN, Stephan WEIDINGER, Rudolf VALENTA, Bodo
NIGGEMANN, Thomas BIEBER, Natalija NOVAK
P-86
Indications for the existence of an isotype-specific signal
transduction via the cytoplasmic tail of membrane bound IgE. Iris
OBERNDORFER, Doris SCHMID, Reto CRAMERI and Gernot ACHATZ
P-87
IgE autoreactivity to human milk allergens due to auto- and crosssensitisation to cow’s milk.Ulrike SCHULMEISTER, Ines SWOBODA,
Santiago QUIRCE, Markus OLLERT, Gabrielle PAULI, Rudolph VALENTA and
Susanne SPITZAUER
P-88
Dendritic Cells In Atopic Dermatitis:Expression of FcepsilonRI on
two distinct inflammation-associated subsets. Georg STARY, Christine
BANGERT, Georg STINGL and Tamara KOPP
P-89
A DNA-based multivaccine against 17kD cross reacting allergens
protects against IgE induction in a mouse model of allergy. Tatjana
STEPANOSKA, Theresa THALHAMER, Martina PRÖLL, Fatima FERREIRA,
Josef THALHAMER, Arnulf HARTL
P-90
CH3 mouse strains are antibody non-responder to the celery allergen
Api g 1 after DNA but not after protein immunization. Angelika
STÖCKLINGER, Romana HOCHREITER, Katharina DOBIAS, Verena FALTIS,
Tatjana STEPANOSKA, Arnulf HARTL, Josef THALHAMER and Peter HAMMERL
Poster Workshop VIII: Immunopathology
Chair: Konrad Schauenstein, Roswitha Sgonc
P-91
Associated Genetic Diseases: Severe Combined Immunodeficiency
and Cystic Fibrosis. Maria CUCURUZ, Maria POP, Estera BOERIU, Margit
SERBAN
P-92
Generation and structural analysis of peptide mimotopes for the
disialoganglioside GD 2,a neuroblastoma tumor antigen. Elisabeth
FÖRSTER-WALDL, Angelika B. RIEMER, Kira BRÄMSWIG, Anna Katherina
DEHOF, Dirk NEUMANN, Georg BOLTZ-NITULESCU, Hubert PEHAMBERGER,
Christoph C. ZIELINSKI, Otto SCHEINER, Arnold POLLAK, Holger LODE
P-93
Injection of CpG motifs and retinoic acid affects the development
of 1-methyl-1-nitrosourea-induced adenocarcinomas. Martin
GAISBERGER, Renata SANOVIC, Sven MOSTBÖCK, Julius BRTKO, Josef
THALHAMER
P-94
A functional screen for molecules that inhibit CD40L induced
apoptosis. F. GÖBEL, L. HEINZ, S. TASCHNER, H. STROBL
Austrian Society for Allergology and Immunology
ÖGAI Annual Meeting, Vienna, Dec. 2 - 4, 2004
Poster Workshops V - VIII: Friday
P-95
STRO-1 Mesenchymal Precursor Cells located in Synovial
Surface Projections of Patients with OA. A. GIUREA, B. RÜGER, D.
HOLLEMANN, G. YANAGIDA, M.B. FISCHER
Room 4
CAPRIOLE
P-96
Induction of OVA expression in the skin under homeostatic
conditions. Martin HOLCMANN, Georg STINGL and Maria SIBILIA
Friday,
Dec 3rd
P-97
Treatment with CD4-specific antibodies amplifies tumor-specific
CD8 responses. P. LÜHRS, R. KUTIL, G. STINGL, A. SCHNEEBERGER
P-98
Atherosclerosis research from past to present – On the track of two
pathologists with opposing views, Carl von Rokitansky and Rudolf
Virchow. Christina MAYERL, Melanie LUKASSER, Roland SEDIVY, Harald
NIEDEREGGER, Ruediger SEILER, Georg WICK
P-99
Possible trigger mechanisms in Behçet’s disease: Comparison
between PCR and antibody findings. Sebastian PHILIPP, Fereydoun
DAVATCHI, Michael SCHIRMER, F. SHAHRAM, M. SEDIGH, N. ZIAEE, Christoph
GASSNER, Harald SCHENNACH,Martina MEYER, Clara LARCHER Dieter
SCHÖNITZER, Wolfgang GÖTTINGER, Hartwig P. HUEMER, Eveline U. IRSCHICK
P-100 Intravenous immunoglobulin (IVIG) in patients with RelapsingRemitting Multiple Sclerosis – towards a better understanding of
the mechanisms of action. Nadine PIGARD, Hanna KUUSISTO, Irina
ELOVAARA, Paalavuo RAIJA, Klaus ZIMMERMANN, Hans-Peter SCHWARZ,
Birgit REIPERT
P-101 The role of TGF-beta 2 in the development offibrosis in UCD-200
chickens, an animal modelfor systemic sclerosis. Martina PRELOG,
Paul SCHEIDEGGER, Georg WICK and Roswitha SGONC
P-102 Matching of trastuzumab (Herceptin®) mimotopes onto the surface
of Her-2/neu – a new means of epitope definition. Angelika B. RIEMER,
Georg KRAML, Otto SCHEINER, Christoph C. ZIELINSKI, Erika JENSEN-JAROLIM
P-103 Alternative splicing of chicken Interleukin-15 and its role in
spontaneous autoimmune thyroiditis. Lisa ROTHWELL, Dusan
VASICEK, Karel HALA, Pete KAISER
P-104 Cytokine Signal Regulators (SOCS) expressed in Precursor Cells
in the Synovial Tissue of Patients with RA and OA. B. RÜGER, A.
GIUREA, AH. WANIVENHAUS, D. HOLLEMANN, G. YANAGIDA, M. GRÖGER,
P. PETZELBAUER, MB. FISCHER
P-105 T cell infiltration in the myelin-degenerative CNS. Roland
GRUNDTNER, Klaus DORNMAIR, Hartmut WEKERLE, Hans LASSMANN and
Monika BRADL
P-106 The differentiation of dendritic cells from mixed glia cultures:
GM-CSF/IL-4 and Flt3-L recruits different subpopulations of cells.
Manuel ZEITELHOFER, Hans LASSMANN and Monika BRADL
P-107 The effects of neuregulin on T cell infiltration in the myelindegenerative CNS. Beate HARTINGER, Manuel ZEITELHOFER, Hans
LASSMANN, and Monika BRADL
P-108 Complementary contribution of CD4 and CD8 T cells to immune
surveillance and the immune response to degeneration in the
spinal cord. Monika BRADL, Jan BAUER, Alexander FLUEGEL, Hartmut
WEKERLE and Hans LASSMANN
14:50 16:20