Imunogenética - Universidade Federal do Paraná
Transcrição
Imunogenética - Universidade Federal do Paraná
MINISTÉRIO DA EDUCAÇÃO UNIVERSIDADE FEDERAL DO PARANÁ SETOR DE CIÊNCIAS BIOLÓGICAS PROGRAMA DE PÓS-GRADUAÇÃO EM GENÉTICA DISCIPLINA: Imunogenética EMENTA: Estruturas dos principais genes e produtos gênicos de importância nas respostas imunes. Diversidade genética e mecanismos (somáticos, evolutivos) que resultam nessa diversidade. Controle genético das respostas imunes. Base(imuno)genética das doenças multifatoriais. REFERÊNCIAS BIBLIOGRÁFICAS: Abbas AK, Lichtman AH, Pober JS. CELLULAR AND MOLECULAR IMMUNOLOGY. 6a edição. Saunders-Elsevier, Philadelphia, 2007. Janeway CA, Travers P, Walport M, Shlomchik M. IMMUNOBIOLOGIA. 6ª edição. Artmed, Porto Alegre. 2007. (Original em inglês: Garland, 2005) Petzl-Erler ML. Genetics of the immune responses and disease susceptibility. Ciência e Cultura 51(3-4):199-211, 1999. Petzl-Erler M. L., Gorodezky C., Layrisse Z., et al. Anthropology Component Report for Region Latin-America: Amerindian and Admixed Populations. In: Charron, D. (Ed.) GENETIC DIVERSITY OF HLA. FUNCTIONAL AND MEDICAL IMPLICATIONS. EDK, Sèvres, França, pp. 337-345, 1997. Uhrberg M. Shaping the human NK cell repertoire: an epigenetic glance at KIR gene regulation. Mol Immunol. 2005 Feb;42(4):471-5. Parham P. MHC class I molecules and KIRs in human history, health and survival. Nat Rev Immunol. 2005 Mar;5(3):201-14. Kim S, Sunwoo JB, Yang L, Choi T, Song YJ, French AR, Vlahiotis A, Piccirillo JF, Cella M, Colonna M, Mohanakumar T, Hsu KC, Dupont B, Yokoyama WM.HLA alleles determine differences in human natural killer cell responsiveness and potency.Proc Natl Acad Sci U S A. 2008; 105(8):3053-8 Rajalingam R, Du Z, Meenagh A, Luo L, Kavitha VJ, Pavithra-Arulvani R, Vidhyalakshmi A, Sharma SK, Balazs I, Reed EF, Pitchappan RM, Middleton D. Distinct diversity of KIR genes in three southern Indian populations: comparison with world populations revealed a link between KIR gene content and pre-historic human migrations. Immunogenetics. 2008; 60(5):207-17. Martin AM, Kulski JK, Gaudieri S, Witt CS, Freitas EM, Trowsdale J, Christiansen FT. Comparative genomic analysis, diversity and evolution of two KIR haplotypes A and B. Gene. 2004 Jun 23;335:121-31. Hsu KC, Chida S, Geraghty DE, Dupont B. The killer cell immunoglobulin-like receptor (KIR) genomic region: gene-order, haplotypes and allelic polymorphism. Immunol Rev. 2002 Dec;190:40-52. Rioux JD, Abbas AK. Paths to understanding the genetic basis of autoimmune disease. Nature. 2005 Jun 2;435(7042):584-9. McClelland EE, Penn DJ, Potts WK. Major histocompatibility complex heterozygote superiority during coinfection. Infect Immun. 2003 Apr;71(4):2079-86. Ziegler A, Kentenich H, Uchanska-Ziegler B. Female choice and the MHC. Trends Immunol. 2005 Sep;26(9):496-502. Review. Tsuneto LT, Probst CM, Hutz MH, Salzano FM, Rodriguez-Delfin LA, Zago MA, Hill K, Hurtado AM, Ribeiro-dos-Santos AK, Petzl-Erler ML. HLA class II diversity in seven CENTRO POLITÉCNICO - JARDIM DAS AMÉRICAS - CAIXA POSTAL 19071 - CEP 81531-990 - CURITIBA, BRASIL 41 3361 1587 [email protected] MINISTÉRIO DA EDUCAÇÃO UNIVERSIDADE FEDERAL DO PARANÁ SETOR DE CIÊNCIAS BIOLÓGICAS PROGRAMA DE PÓS-GRADUAÇÃO EM GENÉTICA Amerindian populations. Clues about the origins of the Ache. Tissue Antigens. 2003 Dec;62(6):512-26. Probst CM, Bompeixe EP, Pereira NF, de O Dalalio MM, Visentainer JE, Tsuneto LT, Petzl-Erler ML. HLA polymorphism and evaluation of European, African, and Amerindian contribution to the white and mulatto populations from Parana, Brazil. Hum Biol. 2000 Aug;72(4):597-617. Braun-Prado K, Vieira Mion AL, Farah Pereira N, Culpi L, Petzl-Erler ML. HLA class I polymorphism, as characterised by PCR-SSOP, in a Brazilian exogamic population. Tissue Antigens. 2000 Nov;56(5):417-27. Parham P, Arnett KL, Adams EJ, Little AM, Tees K, Barber LD, Marsh SG, Ohta T, Markow T, Petzl-Erler ML. Episodic evolution and turnover of HLA-B in the indigenous human populations of the Americas. Tissue Antigens. 1997 Sep;50(3):219-32. Frodsham AJ, Hill AV. Genetics of infectious diseases. Hum Mol Genet. 2004 Oct 1;13 Spec No 2:R187-94. Review. Litman GW, Cannon JP, Dishaw LJ. Reconstructing immune phylogeny: new perspectives. Nat Rev Immunol. 2005 Nov;5(11):866-79. Litman GW. Sharks and the origins of vertebrate immunity. Scientific American, Nov. 1996, pp. 47-51. OMIM - Online Mendelian Inheritance in Man e outros bancos de dados e informações do NCBI: http://www.ncbi.nlm.nih.gov/ IMGT - Immunogenetics Database: http://www.ebi.ac.uk/imgt/ The international ImMunoGeneTics project, is a collection of high-quality integrated databases specialising in Immunoglobulins, T cell receptors and the Major Histocompatibility Complex (MHC) of all vertebrate species. The IMGT project was established in 1989 by the Université Montpellier II and the CNRS (Montpellier, France) and works in close collaboration with the EBI. IPD - Immuno Polymorphism Database: http://www.ebi.ac.uk/ipd/ (HLA Informatics Group of the Anthony Nolan Research Institute in collaboration with the European Bioinformatics Institute). 2 CENTRO POLITÉCNICO - JARDIM DAS AMÉRICAS - CAIXA POSTAL 19071 - CEP 81531-990 - CTBA, BRASIL 41 3361 1587 [email protected]