Davi Marco Lyra-Leite - Usc - University of Southern California
Transcrição
Davi Marco Lyra-Leite - Usc - University of Southern California
Davi Marco Lyra-Leite Contact Information Education Laboratory for Living Systems Engineering USC Viterbi School of Engineering 1042 Downey Way University of Southern California (USC) Los Angeles, CA 90089 Voice: (213) 821-0832 E-mail: [email protected] Site: www-scf.usc.edu/∼leite University of Southern California (USC), Los Angeles, CA, United States of America Philosophy Doctor in Biomedical Engineering (in progress) • Advisor: Megan L. McCain, PhD. • Focus: Cellular and tissue engineering, disease modeling, precision medicine. Master of Science in Biomedical Engineering (in progress) • Focus: Cellular and tissue engineering, disease modeling. Master of Science in Electrical Engineering (in progress) • Focus: Signal processing and medical imaging. Health, Technology and Engineering Certificate (in progress) • Development of innovative technologies for the healthcare industry, analysis of healthcare systems and healthcare economics. University of Brasilia (UnB), Brasilia, DF Brazil Bachelors of Science in Electrical Engineering (graduation: July, 2012) • Advisor: Joao Luiz Azevedo de Carvalho, PhD. • Area of Study: Digital Image and Signal Processing - focus: Medical Imaging, Magnetic Resonance Imaging. Research Projects Laboratory for Living Systems Engineering, USC, Los Angeles, CA United States Extracellular matrix regulation of mitochondria structure and function in engineered cardiac tissues MRI June 2014 to Present • Project under guidance of Professor Megan McCain, PhD. • Comparison of the structure and function of mitochondria in engineered cardiac tissues as a function of extracellular matrix stiffness and tissue alignment. • Academic collaboration with Cedars-Sinai Metabolism and Mitochondrial Research Core. • Research conducted using tissue engineering, micro fabrication, microscopy, image processing, and data analysis. Modeling diabetic cardiomyopathy in vitro MRI October 2015 to Present • Project under guidance of Professor Megan McCain, PhD. • Analysis of the functional and metabolic changes in cardiac myocytes due to diabetic cardiomyopathy. Optical mapping of whole mouse hearts MRI January 2015 to December 2015 • Collaboration project between the Laboratory for Living Systems Engineering and Henry Sucov’s Laboratory. • Development with Yukiko Yamaguchi of an optical mapping system of whole mouse heart to study the effects of the presence of fat in the sinoatrial junction. 1 of 8 Magnetic Resonance Engineering Laboratory, USC, Los Angeles, CA United States Image Formation and Image Analysis for MRI Data MRI September 2012 to May 2014 • Project under guidance of Professor Krishna Nayak, PhD. • Investigation of image analysis and image formation strategies focusing on registration, segmentation and rapid imaging for MR data. • Development of algorithms for image analysis and image formation using Matlab. Toshiba Medical Research Institute USA, Inc, Vernon Hils, IL United States Image Formation for non-contrast enhanced MR Angiography MRI May 2013 to August 2013 • Summer internship research project under guidance of Dr. Mitsue Miyazaki and Professor Krishna Nayak, PhD. • Investigation of image formation algorithms to be used in accelerated non-contrast enhanced MR angiography. • Development of algorithms for image formation using Matlab. Medical Imaging and Signal Processing Research Group (GPSIM), UnB, Brasilia, DF Brazil Reconstruction of Magnetic Resonance Images of Flow using Parallel Imaging MRI June 2010 to November 2012 • Project under guidance of Professor Joao Luiz Carvalho, PhD. • Investigation of the use of parallel imaging in order to increase the acceleration factor of data acquisition from cardiovascular magnetic resonance of flow, obtained using the spiral Fourier Velocity Encoding technique. • Implementation of an image reconstruction algorithms using the iterative self-consistent parallel imaging reconstruction — SPIRiT —, 3D SPIRiT, temporal acceleration schemes and spiral Fourier velocity encoding. • Investigation of the use of multi-dimensional decomposition schemes to reduce noise and improve data reconstruction — under supervision of professor Joao Paulo Carvalho Lustosa da Costa, Dr-Ing. Department of Computer Science (CIC), UnB, Brasilia, DF Brazil Indoor vs Outdoor Scene Classification October to December 2009 • Project under the guidance of Professors Alexandre Zaghetto, Dsc., Bruno Luiggi Espinoza Macchiavello, DSc, and Dibio Leandro Borges, PhD. • Development of a system to be used to identify the nature of an image, whether it was taken in an indoor or outdoor environment, working with aspects of Artificial Intelligence (AI) and Computational Photography. Digital Image and Video Processing Group, UnB, Brasilia, DF Brazil Color Calibration Between Monitors and Printers Aug 2009 to September 2010 • Scientific Initiation Project of the Scientific Initiation Program at the University of Brasilia (ProIC) under the guidance of Professor Ricardo Lopes de Queiroz, PhD, and Professors Camilo Chang Dorea, PhD, and Alexandre Zaghetto, DSc. • Development of a system to be used for color calibration between monitors and printers using a digital camera. Teaching Experience Department of Biomedical Engineering USC January 2015 to May 2015 • Teaching assistant in the course BME 410 Introduction to Biomaterials and Tissue Engineering of 51 students. IEEE Student Branch University of Brasilia (SB IEEE UnB) 2 of 8 June 2012 • Taught a MATLAB course for undergraduate students and engineering professionals, total of 28 students. Department of Electrical Engineering UnB (ENE) March 2011 to August 2011 • Teaching assistant and grader in the course ENE 169111 Theory of Communications of 20 students. • Supported students during the course period with coursework assessment, and lecturing review sessions. • Aided the teachers in correcting the laboratory assignments and computational projects. Department of Computer Science, UnB (CIC) March 2010 to March 2011 • Teaching assistant in the course CIC 117242 Introduction to Digital Image Processing of 15 students over two semesters. • Supported students during the course period, especially with assignments and final projects. • Graded the student’s assignments for different course projects. Dean of Extension, UnB (DEX) April 2009 to February 2010 • Teaching assistant in the discipline DEX 200212 Construction of Social and Multidisciplinary Projects instructional team of 100 students over two semesters. • Provided in-class and on-line support to students during the construction of workshops and classes to be applied during the Rondon Project – a nationwide outreach activity focusing on aiding deprived communities. Professional Experience Toshiba Medical Research Institute USA, Inc., Vernon Hills, IL, USA Clinical Research Intern May to August 2013 • Clinical research intern in MRI, working under supervision of Dr. Mitsue Miyazaki. Podion Preparatory Course and Instituto Tecnologico de Aprovacao, Brasilia, DF Brazil Tutor April 2008 to Oct 2010, and Feb to August 2012 • Physics, Chemistry and Mathematics tutor in the High School and pre-admission test levels. Teacher September 2009 to Oct 2010, and Apr to August 2012 • Taught review and advanced level lectures on Physics and Chemistry to students in high school and pre-admission test levels, lecturing to more than 200 students over one year and a half. Extension and Outreach Activities Mercado Popular Columnist and Editor January 2015 to present • Writes articles related to public policy, science, education and healthcare. • Edits the articles on public policy and economic welfare. IEEE Student Branch University of Brasilia (SB IEEE UnB) Events Committee April 2011 to July 2012 • Organized seminars and courses promoted by the Student Branch of IEEE at the University of Brasilia. • Elaborated documents to be used by the SB in projects and proposals submitted to the University and to the IEEE. Dean of Extension, University of Brasilia (DEX) Projeto Rondon September 2008 to February 2010 3 of 8 • Visited three cities: Palmital de Minas and Cabeceira Grande, in Minas Gerais; and Itaruma, in Goias, in order do conduct workshops and seminars. • Workshops and seminars focused on: general topics of health (personal care, sexual education, diabetes and hypertension); entrepreneurship (how to organize cooperatives and associations); and techniques of recycling. • Worked alongside students from different majors and universities in order to improve life standard and to change social paradigms of the visited communities. Alianca Pela Liberbedade - Student Association Founding Member and Advisor May 2009 to present • Worked with students from different areas in the University of Brasilia student movement. • Helped organizing seminars, guest lectures, workshops, and campaigns for Undergraduate Student Government (DCE) and students’ representation in the University’s superior councils (CEPE, CAD, Consuni). • Writes articles for the group’s website focusing on education and scientific research. Journal Papers LYRA-LEITE DM, da COSTA JPCL, CARVALHO JLA. Improved MRI reconstruction and denoising using singular values decomposition approximation. Revista Ingenieria, Vol 17, No 2, Bogota, Colombia, 2012. International Conferences LYRA-LEITE DM, NAYAK KS, CARVALHO JLA. Acceleration of spiral Fourier velocity encoded MRI using 3D SPIRiT. Abstract 1352, presented at the 21st ISMRM Annual Meeting & Exhibition and published in the conference proceedings, 2013. LYRA-LEITE DM, CARVALHO JLA. Parallel imaging acceleration of spiral Fourier velocity encoded MRI using SPIRiT. Presented at the 34th Annual International Conference of the IEEE Engineering in Medicine & Biology Society and published in the conference proceedings, 2012. LYRA-LEITE DM, CARVALHO JLA. Accelerated spiral Fourier velocity encoded MRI using SPIRiT parallel imaging. Abstract 1820, presented at the 20th ISMRM Annual Meeting & Exhibition and published in the conference proceedings, 2012. LYRA-LEITE DM, da COSTA JPCL, CARVALHO JLA. Improved MRI reconstruction and denoising using SVD-based low-rank approximation. Presented at the 2012 IEEE Workshop on Engineering Applications and published in the conference proceedings, 2012. MARINS AA, LYRA-LEITE DM, da COSTA JPCL. Simulations of a Dynamical System Model for Electronic Circuits. Presented at the 2012 IEEE Workshop on Engineering Applications and published in the conference proceedings, 2012. American Conferences ARIYASINGHE NR, PETERSEN AP, RECK C, HSU J, LYRA-LEITE DM, MCCAIN ML. Extracellular Matrix Regulation of the Structure and Contractility of Engineered Cardiac Tissues. Proceedings 25th Annual Meeting, Biomedical Engineering Society, 2015. CHO N, HSU J, LYRA-LEITE DM, MCCAIN ML. Regulation of Cardiac Fibroblast Proliferation by Extracellular Matrix Elasticity. Proceedings 25th Annual Meeting, Biomedical Engineering Society, 2015. Brazilian Conferences LYRA-LEITE DM, CARVALHO JLA. Reconstrucao de Imagens de Ressonancia Magnetica de Fluxo com Imageamento Paralelo II (Reconstruction of Magnetic Resonance Images of Flow with Parallel Imaging II). Presented at the 9th Distrito Federal’s Scientific Initiation Congress, 4 of 8 2012. (in Portuguese) LYRA-LEITE DM, CARVALHO JLA. Aceleracao por imageamento paralelo de um exame de ressonancia magnetica de fluxo cardiovascular. Presented at the XIII Brazilian Congress of Biomedical Engineering, 2012. (in Portuguese) LYRA-LEITE DM, da COSTA JPCL, CARVALHO JLA. Reconstrucao melhorada de dados de ressonancia magnetica usando aproximacao de ordem baixa baseada em decomposicao por valores singulares. Presented at the XIII Brazilian Congress of Biomedical Engineering, 2012. (in Portuguese) LYRA-LEITE DM, CARVALHO JLA. Reconstrucao de Imagens de Ressonancia Magnetica de Fluxo com Imageamento Paralelo (Reconstruction of Magnetic Resonance Images of Flow with Parallel Imaging). Presented at 8th Distrito Federal’s Scientific Initiation Congress, 2011. (in Portuguese) LEITE DML, de QUEIROZ RL. Calibracao de Cores entre Monitores e Impressoras (Colour Calibration amongst Monitors and Printers). Presented at 7th Distrito Federal’s Scientific Initiation Congress, 2010. (in Portuguese) LEITE DML, FARIA DO, de QUEIROZ RL, ZAGHETTO A, DOREA CC. Calibracao de Dispositivos a Cores usando uma Camera Digital (Calibration of Color Devices using a Digital Camera). Presented at the Workshop of the Post-Graduation in Computer Science from the Department of Computer Science at UnB and published in the conference proceedings, 2009. (in Portuguese) Other Publications LYRA-LEITE DM, CHO N, ARIYASINGHE NR, HSU J, STRICKLAND J, MCCAIN ML. Regulation of Mitochondrial Function by Tissue Architecture and Matrix Elasticity in Engineered Cardiac Tissues. Presented at the 20th Fred S. Grodins Biomedical Engineering Graduate Research Symposium and at the 2016 USC Stem Cell and Developmental Biology Retreat, 2016. PETERSEN AP, LYRA-LEITE DM, ARIYASINGHE NR, CHO N, KIM JY, STRICKLAND J, MCCAIN ML. Matrix Elasticity Regulates Conduction Velocity in Engineered Cardiac Tissues. Presented at the 20th Fred S. Grodins Biomedical Engineering Graduate Research Symposium and at the 2016 USC Stem Cell and Developmental Biology Retreat, 2016. ARIYASINGHE NR, RECK CH, PETERSEN AP, LYRA-LEITE DM, HSU J, MCCAIN ML. Extracellular Matrix Regulation of the Structure and Contractility of Engineered Cardiac Tissues. Presented at the 20th Fred S. Grodins Biomedical Engineering Graduate Research Symposium and at the 2016 USC Stem Cell and Developmental Biology Retreat, 2016. LYRA-LEITE DM, ARIYASINGHE NR, HSU J, STRICKLAND J, MCCAIN ML. Extracellular matrix regulation of mitochondrial membrane potential in engineered cardiac tissues. Presented at the USC-UCLA-UCSF Tri-Institutional Stem Cell Retreat, 2015. CHO N, HSU J, LYRA-LEITE DM, MCCAIN ML. Regulation of Cardiac Fibroblast Proliferation by Extracellular Matrix Elasticity. Presented at the USC-UCLA-UCSF Tri-Institutional Stem Cell Retreat, 2015. ARIYASINGHE NR, HSU J, PETERSEN AP, RECK C, LYRA-LEITE DM, MCCAIN ML. Extracellular Matrix Regulation of Engineered Cardiac Tissue Contractility. Presented at the USC-UCLA-UCSF Tri-Institutional Stem Cell Retreat, 2015. CHO N, HSU J, LYRA-LEITE DM, MCCAIN ML. Regulation of Cardiac Fibroblast Prolif- 5 of 8 eration by Extracellular Matrix Elasticity. Presented at the 19th Fred S. Grodins Biomedical Engineering Graduate Research Symposium, 2015. ARIYASINGHE NR, HSU J, PETERSEN AP, RECK C, LYRA-LEITE DM, MCCAIN ML. The Combined Effects of Matrix Composition and Elasticity on the Structure and Function of Cardiomyocytes. Presented at the 19th Fred S. Grodins Biomedical Engineering Graduate Research Symposium, 2015. LYRA-LEITE DM. Reconstrucao de Imagens de Ressonancia Magnetica com Imageamento Paralelo (Reconstruction of Magnetic Resonance Images with Parallel Imaging). IEEE R9 Student Paper Contest. Brasilia, DF Brazil, 2011. (in Portuguese) (Awarded the 2nd Best Paper in Electrical Engineering) Awards and Honors USC Graduate School • Annenberg PhD Fellowship, 2012-16. Dean of Education and Undergraduate Studies (DEG) of UnB • Travel Grant (ISMRM Annual Meeting and Exhibition), 2012. International Society for Magnetic Resonance in Medicine • Educational Stipend, 2012, 2013. Institute of Electrical and Electronics Engineers Region 9 • 2nd Position, IEEE R9 Student Paper Contest (Electrical Engineering), 2011. Dean of Research and Graduate Studies (DPP) of UnB • Scientific Initiation Fellowship (Color Constancy and Calibration of Optical Devices), 2009. • Scientific Initiation Fellowship (Reconstruction of Magnetic Resonance Images of Flow Using Parallel Imaging), 2010. • Scientific Initiation Fellowship (Reconstruction of Magnetic Resonance Images of Flow Using Parallel Imaging II), 2011. Conferences and Workshops 2016 USC Stem Cell and Developmental Biology Retreat Galen Center, Los Angeles, CA United States San Diego May 24th , 2016 20th Fred S. Grodins Biomedical Engineering Graduate Research Symposium University of Southern California, Los Angeles, CA United States San Diego April 1st , 2016 USC-UCLA-UCSF Tri-Institutional Stem Cell Retreat The Fess Parker, Santa Barbara, CA United States San Diego May 17 to 19th , 2015 4th Annual Ming Hsieh Department of Electrical Engineering Research Festival University of Southern California, Los Angeles, CA United States San Diego October 11th , 2013 ISMRM 21st Annual Meeting and Exhibition Salt Place Convention Center, Salt Lake City, Utah United States Melbourne April 20 to 26th , 2013 3rd Annual Ming Hsieh Department of Electrical Engineering Research Festival 6 of 8 University of Southern California, Los Angeles, CA United States San Diego February 6th , 2013 34th Annual International Conference of the IEEE Engineering in Medicine & Biology Society Hilton San Diego Bayfront, San Diego, CA United States San Diego August 28 to September 1st , 2012 ISMRM 20th Annual Meeting and Exhibition Melbourne Convention and Exposition Centre, Melbourne, VIC Australia Melbourne May 5 to 11th , 2012 10th Week of the Department of Electrical Engineering October 3 to 7th , 2011 University of Brasilia, Brasilia, DF Brazil • Member of organizing committee; • Coordinator of the event’s press committee and social media (Facebook page and Twitter account); • Editor and writer of the event’s official blog, which published reviews about the conferences and lectures that occurred during the Week. 8th Distrito Federal’s Scientific Initiation Congress September 12 to 15th , 2011 University of Brasilia, Brasilia, DF Brazil 3rd National Forum on Innovation in Healthcare in Brazil April 7th , 2011 Brazilian Institute of for Responsible Action, Brasilia, DF Brazil 1st Distrito Federal’s Seminar on Health Technologies Assessment Health Technologies Assessment Nucleus, Distrito Federal’s Bases Hospital, Brasilia, DF Brazil February 28th , 2011 7th Distrito Federal’s Scientific Initiation Congress University of Brasilia, Brasilia, DF Brazil November 8 to 11th , 2010 Brazilian Symposium on Electrical Systems Brazilian Automatic Society, Belem, PA Brazil Related Education May 18 to 21th , 2010 Coursera, On-line Education Stanford University October 10th to December 19th , 2011 Machine Learning Duke University January 14th to March 18th , 2013 Image and Video Processing University of Brasilia, Brasilia, DF Brazil Electroencephalography with Tensors Programming Course C/C++ Neural Networks and Fuzzy Logic MATLAB Course – ENETEC 7 of 8 October 3 to 7th , 2011 February 22nd to March 5th , 2010 October 5 to 9th , 2009 October 7 to 28th , 2008 Professional Societies Student Student Student Student Student Member, Member, Member, Member, Member, American Heart Association Biomedical Engineering Society (BMES) the Institute Electrical and Electronics Engineers (IEEE) IEEE Signal Processing Society IEEE Engineering in Medicine and Biology Society Languages Portuguese (Native Language) English (Fluent - Second Language) Holds a Test of English as Foreign Language (TOEFL) internet based test (iBT) score of 108. Exam taken in September 2011. Spanish (Advanced) Fluent reading, excellent writing, listening and good speaking levels. French (Advanced) Finished the advanced level course at UnB Idiomas — University of Brasilia Language School — in July 2012. Catalan (Basics) Good reading comprehension. Technical Skills Matlab experience: image and signal processing, neural networks, Fourier transforms. Matlab toolboxes: image processing, neural networks, signal processing, svmdecision, image formation, image registration, SPIRiT, nuFFT. Programming: C, C++, Pascal, VHDL, VRML, Matlab Applications: TEX, LATEX, Autocad, ImageJ, CosmoWorlds, Hiperion, Multisim, Microsoft Office, and other common productivity packages for Windows. Operating Systems: Microsoft Windows, Mac OSX, Ubuntu, iOS and Android Microscopy: Nikon wide-field and confocal. Micro fabrication: photolitography, microcontact printing. Tissue culture: maintenance of mammalian differentiated cells and cell lines, cell isolation from tissue samples. Last Update: May 27, 2016 8 of 8