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Quality of life analysis in patients with gastrectomy due to gastric adenocarcinoma Jacqueline Nunes de Menezes¹, Giovanna Luiza Caxeiro¹, Isabella Asari Takahara¹, Bianca Escorel Costa Fava², Marcelo Cerdan Torres², Franz Robert Apodaca¹ ² ¹ Universidade de Mogi das Cruzes – SP ² Hospital das Clínicas Luzia de Pinho Melo – Mogi das Cruzes – SP. Quality of life analysis in patients with gastrectomy due to gastric adenocarcinoma • Introduction: Gastric cancer is one of • Methods: - 28 patients diagnosed with histopathology of gastric adenocarcinoma the main death causes worldwide. In with total or subtotal gastrectomy were Brazil, it is the third most frequent included. malignant neoplasia among men and – They had at least a six-month-postthe fifth among women. Surgeries surgery period from 1/2013 to 12/2014. are the main treatment and they can – They were requested to answer the be associated with quality of life (QL) EORTC QLQ – European Organization for jeopardy. Research in the Treatment of Cancer Quality of Life Questionnaire in • Objectives: Analyzing the QL of Portuguese, divided in: EORTC QLQ – C30 patients with total or subtotal and EORTC QLQ – STO22 (Gastric gastrectomy due to gastric Module). adenocarcinoma. • Results: (Abstention rate = 7,2%) TABELA 1. Distribuição da Escala Funcional - Escores EORTC QLQ-C30 Variável Medidas FIGURAS 1 e 2. Análise de QV: gastrectomia total x gastrectomia subtotal. Medidas Estado global de saúde/qualidade de vida Variação Mediana Média (Desvio Padrão) 25 – 100 87,5 80,4 (22,6) Função física Variação Mediana Média (Desvio Padrão) 13,3 – 100,0 86,7 75,4 (26,2) Desempenho de papel Variação Mediana Média (Desvio Padrão) 0,0 – 100,0 100,0 78,2 (32,2) Função emocional Variação Mediana Média (Desvio Padrão) 0,0 – 100,0 91,7 83,3 (24,0) Função cognitiva Variação Mediana Média (Desvio Padrão) 0,0 – 100,0 83,3 78,2 (27,4) Função social Variação Mediana Média (Desvio Padrão) 50,0 – 100,0 100,0 87,8 (18,0) p=0,021 p=0,009 - Higher symptomology rates have been associated with patients with a total gastrectomy; - Body image perception (p=0,048) was worse in those who had undergone any post surgery complication. FIGURAS 3, 4 e 5. Análise de QV de acordo com o período de internação. p=0,010 p=0,033 p=0,030 FIGURAS 5 e 6. Análise de QV de acordo com o estadio clínico da população estudada. p=0,017 p=0,031 • Conclusions: – Total gastrectomy, advanced clinical stage and long hospital stay are factors associated with the worse QL in patients with gastrectomy. – More studies aiming to improve the understanding of gastrectomy impact on QL are necessary. Autor a ser contatado: Jacqueline Nunes de Menezes Rua Fernando Pessoa, 1246. Parque Marajoara – Santo André – SP. (11) 99525-1728 [email protected]