RÉSUME – November 2015 JOÃO LAURO VIANA DE

RÉSUME – November 2015
JOÃO LAURO VIANA DE CAMARGO, MD, PhD, FIATP
https://www.researchgate.net/profile/Joao_Lauro_De_Camargo
https://www.linkedin.com/profile/view?id=118817378&trk=spm_pic
A CARRIER DEVELOPMENT
1991 Associate Professor
Departament of Pathology, Botucatu Medical School
(FMBo), UNESP, Brazil
FMBo, UNESP
1989 Pos-Doc
Nagoya City Univ. Medical School, Japan
1983 Pos-Doc
Massachusetts Institute of Technology, MIT, USA
1981 Ph.D.
FMBo, UNESP
1978 M. Sc.
FMBo, UNESP
Brazilian Society of Pathology Board Qualified
1998 Full Professor
1973 Pathologist
1971 M.D.
Catholic University at São Paulo Sorocaba (PUC/SP)
B CURRENT POSITIONS
B.1 Permanent Faculty and Supervisor, Post-graduate Program in Pathology (CAPES,
rank 5,0), FMBo, since 1992.
B.2 Research Fellow, National Council for Research (CNPq), Ministry of Science and
Technology, Brazil, since 1998.
B.3 Coordinator, Centre for Evaluation of the Environmental Impacto n Human Health
(TOXICAM), FMBo, since 1996.
B.4 Faculty member, Latin America Risk Assessment Workshop (LARAW), held
annualy by the International Union of Toxicology (IUTOX) and by the Brazilian Society
of Toxicology (SBTox), Águas de São Pedro, SP, since 2008.
B.5 Fellow - International Academy of Toxicologic Pathology (IATP), 2014.
B.6 Roster member (2011-2016), JMPR (Joint Meeting for Pesticides Residues,
FAO/World Health Organization).
B.7 Member, Committee for Environmental Health Reference, São Paulo State
Secretary of Health, SP, Brazil.
B.7 Member, Scientific Consulting Committee (C3) - International Life Science Institute,
Brazil (ILSI/Brazil).
B.8 Editorial Board, European Journal of Toxicological Sciences, ISRN, Applied
Research in Toxicology.
B.9 Consulting or ad hoc referee – Brazilian governmental agencies: ANVISA, CTNBio,
IBAMA, CNPq, FAPESP, Scientific journals: Toxicol Pathol, Crit Rev Toxicol, Food
Chem Toxicol, Histol Histopathol, Inter J Biotech, Braz J Med Biol Res. Private
companies: BASF, Bayer, DuPont, Monsanto, Ihara, Adama, etc.
C OTHER POSITIONS DURING THE LAST 10 YEARS
1998-2011
1974-2011
Full Professor
(retired in 2011)
Pathologist
Department of Pathology, FMBo, UNESP
UNESP General Hospital
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RÉSUME – November 2015
JOÃO LAURO VIANA DE CAMARGO, MD, PhD, FIATP
UNESP General Hospital – São Paulo State
Secretary of Health
Toxicol. Pathol., J. Bras. Patol. Med. Lab., Rev.
Bras. Toxicol.
Latin American Society of Toxicologic and
Experimental Pathology (LASTEP)
São Paulo State Oncology Center Foundation
(FOSP)
2011-2013
Dean for Academic Affairs
2006-2013
Editorial Board
2005-2010
Two-term President
2004-2008
Board member
1993-1997
Vice-Dean
FMBo, UNESP
1986-1990
Supervisor
Division for Medical Support, UNESP General
Hospital
1984-1986
Head of Department
Department of Pathology, FMBo, UNESP
1974-1991
Assistant Professor
Department of Pathology, FMBo, UNESP
D POS-DOC TRAINING
1988-1989, Japan - Nagoya University Medical School, Department of Pathology. Fellow of the
Japanese Foundation for Cancer Research, Tokyo. Development of medium-term alternative
bioassays for chemical carcinogens identification. Necropsies of rodents submitted to
conventional long-term bioassays at the Dai-Yukai Institute of Medical Sciences (DIMS).
Supervisor: Dr. Nobuyuki Ito.
1981-1984, USA – Visiting scientist, Massachusetts Institute of Technology (MIT), Department
of Nutrition and Food Science, Laboratory of Animal Pathology. Lipotropes deficiency; focus on
B6C3F1 mice liver toxicity. In vivo evaluation of the tricotecenic mycotoxin anguidine in the CD1 mice. Supervisor: Dr. Paul M. Newberne.
E PUBLICATIONS (Last 05 years)
E.1 Fava RM, Cardoso APF, da Rocha MS, Nascimento e Pontes MG, de Camargo JLV, de
Oliveira MMCS. Evaluation of early changes induced by diuron in the rat urinary bladder usinf
different processing methods for scanning electron microscopy. Toxicology, 333:100-106, 2015.
doi: 10.1016/j.tox.2015.04.006
E.2 Pascotto \VM, Guerra MT, Franci JAA, de Camargo JLV, Kempinas WG, Franchi CAS.
Effects of a mixture of pesticides on the adult female reproductive system of Sprague-Dawley,
Wistar, and Lewis rats. J. Toxicol. Environ. Health, Part A, 78 (9):602-606.
doi:
10.1080/15287394.2015.1010467
E.3 Solano MLM, Montagner CC, Vaccari C, Jardim WF,, Anselmo-Franci JA, Carolino ROG,
Luvizutto JFL, Umbuzeiro GA, de Camargo JLV. Potential endocrine disruptor activity of
drinking water samples. Endocrine Disruptors. http://dx.doi.org/10.4161/23273747.2014.983384
E.4 Luvizutto JFL, Solano MLM, Martinez MF, Fernadez CDB, Umbuzeiro GA, de Camargo
JLV. Potential androgenic effects of urban sewage sludge in male rats. Endocrine Disruptors.
http://dx.doi.org/10.1080/23273747.2015.1066656
E.5 Ihlaseh-Catalano SM, Bailey K, Cardoso APF, Ren H, Fry R, de Camargo JLV, Wolf DC.
Dose and temporal effects on gene expression profiles of urothelial cells from rats exposed to
diuron. Toxicology, 325: 21-230, 2014. doi: 10.1016/j.tox.2014.08.005
E.6 da Rocha MS, Arnold LL, de Oliveira MLCS, Catalano SMI, Cardoso APF, Pontes MGN,
Ferrucio B, Dodmane PR, Cohen SM, de Camargo JLV. Diuron-induced rat urinary bladder
carcinogenesis: Mode of action and human relevance evaluations using the International
Programme on Chemical Safety framework. Crit. Rev.Toxicol., 44(5):393-406, 2014. doi:
10.3109/10408444.2013.877870
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RÉSUME – November 2015
JOÃO LAURO VIANA DE CAMARGO, MD, PhD, FIATP
E.7 Marcondes JPC, de Oliveira MLCS, Gontijo AM, de Camargo JLV, Salvadori DMF.
Genetic instability persists in non-neoplastic urothelial cells from patients with a history
ofurothelial cell carcinoma. PLOS One, 9:e86162-e86162, 2014. doi: 101371/
journal.pone.0086162
E.8 de Camargo JLV. Chemical carcinogenesis – mode of action to inform quantitative human
risk. BMC Proceedings, 2013, 7 (Suppl 2):K10. doi:10.1186/1753-6561-7-S2-K10
E.9 da Rocha MS, Arnold, LL, Dodmane PR, Pennington KL, Qiu F, de Camargo JLV, Cohen
SM. Diuron metabolites and urothelial cytotoxicity: In vivo, in vitro and molecular approaches.
Toxicology, 314: 238-246, 2013. doi:10.1093/toxsci/kfs256
E.10 da Rocha MS, Arnold LL, Pennnington KL, Muirhead D, Dodmane PR, Anwar MM,
Battalora M, de Camargo JLV, Cohen SM. Diuron-induced rat bladder epithelial cytotoxicity.
Toxicol. Sci.,130 (2): 281-288, 2012. doi:10.1093/toxsci/kfs256
E.11 Cardoso APF, Catalano SMI, da Rocha MS, Pontes MGN, de Camargo JLV, Oliveira
MLCS. Dose-response of diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] in the urothelial
mucosa of Wistar rats. Toxicology, 312:1-5, 2013. doi.org/10.1016/j.tox.2013.07.007
E.12 de Camargo MR, Barbisan LF, Martinez MF, Da Franchi, CAS, de Camargo JLV,
Spinardi-Barbisan ALT. Macrophage activity and histopathology of the lymphohematopoietic
organs in male Wistar rats orally exposed to single or mixed pesticides. J. Environ. Sci. Health.
Part B. Pest. Food Contam. Agr. Wastes. 48: 607-613, 2013. doi: 10.1080/03601234.2013.
775020
E.13 Ihlaseh SM, Drigo S, Jesus CMN, Domingues MA, Trindade Filho JCS, Soares FA, de
Camargo JLV, Rogatto SR. STEAP1 protein overexpression is an independet marker for
biochemical recurrence in prostate carcinomas. Histopathology, 63(5):678-85, 2013. doi:
10.1111/his.12226.
E.14 Toledo Netto P, Teixeira Jr. OJ, de Camargo JLV, Ribeiro ML, de Marchi MRR. A rapid,
environmentally friendly, and reliable method for pesticide analysis in high-fat samples. Talanta
(Oxford), 101: 322-329, 2012. doi: 10.1016/j.talanta.2012.09.034
E.15 Nascimento e Pontes MG, Silveira SM, Trindade Filho JC, Rogatto SR, de Camargo JLV.
Chromosomal imbalances in successive moments of human bladder urothelial carcinoma.
Urologic Oncol.: Seminars and Original Investigations, doi:10.1016/j.urolonc.2011.05.015.
E.16 de Camargo JLV, Barros SBM. Informação científica e avaliação do risco toxicológico.
Rev. Bras. Toxicol., 24:1- 9, 2011.
E.17 Ihlaseh SM, Bailey KA, Hester SD, Jones C, Ren H, Cardoso APF, Oliveira MLCS, Wolf
DC, de Camargo JLV. Transcriptional profile of diuron-induced toxicity on the urinary bladder of
male Wistar rats to inform mode of action. Toxicol. Sci., 122: 330-338, 2011. doi: 10.1093/
toxsci/kfr108.
E.18 Grassi TF, Rodrigues MAM, de Camargo JLV, Barbisan LF. Evaluation of carcinogenic
potential of diuron in a rat mammary two-stage carcinogenesis model. Toxicol. Pathol., 39: 486495, 2011. doi: 10.1177/0192623310396904
E19 Ferrucio B, Franchi CAS, Boldrin N, de Oliveira MLCS, de Camargo JLV. Evaluation of
diuron (3-[34-dichlororophenyl]-1-1-dimethylurea) in a two-stage mouse skin carcinogenesis
assay. Toxicol. Pathol., 38(5):756-764, 2010. doi: 10.1177/0192623310375452
E20 da Rocha MS, Nascimento MG, Cardoso APF, de Lima LA; Zelandi E, de Camargo JLV,
de Oliveira MLCS. Cytotoxicity and regenerative proliferation as the mode of action for diuroninduced urothelial carcinogenesis in the rat. Toxicol. Sci., 113:37-44, 2010.
doi:10.11.093/toxsci/kfp241
E.21 Luvizutto JFL, Solano MLM, Passareli D, Franchi CAS, Umbuzeiro GA, de Camargo JLV.
Subchronic toxicity evaluation of treated urban sewage sludge. J. Toxicol. Environ. Health Part
A, 73: 916-925, 2010. doi: 10.1080/152873910037 45036
E.22 Perobelli JE, Martinez MF, Franchi CAS, Fernandez CAD, de Camargo JLV, Kempinas
WG. Decreased sperm motility in rats orally exposed to single or mixed pesticides. J. Toxicol.
Environ. Health, Part A, 73:991-1002, 2010. doi: 10.1080/15287391003751802
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RÉSUME – November 2015
JOÃO LAURO VIANA DE CAMARGO, MD, PhD, FIATP
E.23 de Camargo JLV. Brazilian experience with the medium-term multi-organ bioassay:
scientific and regulatory developments. Asian Pacific J. Cancer Prev., 11:7-8, 2010.
E.24 Said RA, Grassi TF, Scolastici C, de Lima ROA, Darros B, Barbisan LF, de Camargo JLV.
Absence of chemopreventive influence of propolis on the rat liver altered foci development.
Exper. Toxicol. Pathol., 62: 405-412, 2010. doi:10.1016/ j.etp.2009.05.012
F BOOKS AND BOOK CHAPTERS (Last 5 years)
F.1 Rodrigues MAM, de Camargo JLV. Carcinogênese. IN: Mario R. Montenegro, Marcello
Franco. (Org.) Patologia - Processos Gerais. 5ª. Edição. Ed. Atheneu, 2010. p. 255272.[Portuguese]
F.2 Rodrigues MAM, de Camargo JLV. Doenças Nutricionais IN: Mario R. Montenegro,
Marcello Franco (Org.) Patologia - Processos Gerais. 5ª Edição. Ed. Atheneu, 2010. p. 287305.[Portuguese]
F.3 de Camargo JLV. Identificação do Potencial Cancerígeno. IN: Cristiana L. Corrêa; Ione P.
Lemonica; Flávio A.D. Zambrone; J.L.V. de Camargo (Org.). Bases Científicas para a
Avaliação da Toxicidade de Agrotóxicos. 1ª. Ed. São Paulo: ILSI Brasil International Life
Science Institute do Brasil. 2009. p. 131-169.[Portuguese]
F.4 de Camargo JLV e Oliveira DE (Org.). Patologia Geral: Abordagem Multidisciplinar. 1ª. Ed.
Rio de Janeiro: Guanabara-Koogan. 2007. 5ª. reimpressão (2012). 204 p. .[Portuguese]
G BIOASSAY PROTOCOL - OFFICIAL ACCEPTANCE
G.1 IBAMA (Brazilian Institute for the Environment) Technical Norm # 84/1996 – Protocol of an
alternative in vivo assay for the detection of the carcinogenic potential of pesticides.
H ORGANIZATION AND COORDENATION OF SCIENTIFIC MEETINGS (Last five years)
H.1. III Brazilian Symposium on “Toxicologic Pathology and the Safety of Industrial Chemicals”,
ALAPT/ILSI/IFSTP, São Paulo, March 2010.
H.2. Symposium on “Environmental Pathology”, during the International Academy of Pathology
(IAP) Congress, São Paulo, SP, October 2010.
I INVITED TALKS (Last five years)
I.1 “Evaluation of the safety of genetically modified food/feed (GMF)”. National Technical
Committee of Biotechnology (CTNBio). Brasília, DF, November 06th, 2014.
1.2 “Pathogenseis of cancer and MoA of putative human carcinogens”. Workshop “Mode of
Action (MoA): desenvolvimentos recentes e aplicação regulatória”. Intl. Life Science
th
Institute/Brasil, Brasília, DF, April, 14-15 , 2014.
I.2 “Chemical carcinogenesis – mode of action to inform quantitative human risk”. Keynote
Lecture Presentation. São Paulo Advanced School of Comparative Oncology/FAPESP. Águas
de São Pedro, SP. September, 30th, 2012.
I.3 ”In vivo toxicity testing in Brazil – today and tomorrow”, Symposium “Alternative and in vitro
methods for the safety of chemicals and their impact to the health and the environment:
updating and perspectives”. UNESP/São Paulo State University Symposium. São Paulo/SP,
Outubro, 2010.
I.4 “Chemical carcinogenesis: from the bench to regulation”. III International Meeting of
Investigative Pathology. Hospital A.C. Camargo, São Paulo/SP, August, 2010.
J RESEARCH GRANTS (Last five years)
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RÉSUME – November 2015
JOÃO LAURO VIANA DE CAMARGO, MD, PhD, FIATP
J.1 FAPESP 2011/09870-2. “In vivo evaluation of endocrine disrupting potential of treated
sewage sludge, drinking water and of a pesticide mixture”.
J.2 FAPESP 2009/02754-7. “Gene expression in the urothelium of male Wistar rats exposed to
the herbicide Diuron (3-(3,4-dichlorophenyl)-1,1-dimethylurea”.
K POS-DOC SUPERVISION
K.1 Merielen G. Nascimento e Pontes, Ph.D., 2012-2015. “Establishment of a testicular germ
cell tumor model in Sprague-Dawley rats”. FAPESP Proc. No. 2012/09873-4.
L SUPERVISION OF GRADUATION PROJECTS
L.1 Ph.D., Viviane M. Pascotto. “Evaluation of the individual or mixed influences of the
fungicides prochloraz, propiconazole and miclobutanil on the reproductive system of female
Sprague-Dawley rats”.
L.2 Ph.D., Ana Paula F. Cardoso. “Cryptorchidism establishment in Sprague-Dawley rats”.
L.3 M.Sc., Nathalia P. de Souza, CNPq 132667/2013-4. “Cryptorchidism and in utero exposure
to di(n-butyl)phtalate or to acrylamide – evaluation of SD rats Leydig cells”.
L.4 M.Sc., Ligia M. M. Rodrigues, CNPq 830850/1999-6. “Evaluation of Sertoli cells
development and ultrastructure in an experimental modelo of cryptorchidism and orchidopexia”.
M SCIENTIFIC SOCIETIES
International Academy of Toxicologic Pathology (IATP, 2014)
Society of Toxicology (SoT, 2011)
Latin-american Society of Toxicologic and Experimental Pathology (LASTEP, 2005)
Brazilian Society of Toxicology (SBTox, 1992)
The Society of Toxicology Pathology (STP) (1996)
American Association for Cancer Research (AACR) (1989)
Brazilian Society of Pathology (SBP, 1972)
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