Drogenschnelltest-Gebrauchsanweisung | Dip / Multi-Dip

Transcrição

Drogenschnelltest-Gebrauchsanweisung | Dip / Multi-Dip
Drogenschnelltest-Gebrauchsanweisung | Dip / Multi-Dip
Deutsch
1.
Anwendungsbereich
5. Cut-offs
Einstufige Sandwich-Immunoassays zur qualitativen Bestimmung verschiedener
Drogen und Drogenmetaboliten im humanen Urin. Der Test ist nur für den
professionellen Gebrauch vorgesehen (medizinische Fachkreise).
2. Testdurchführung
1) Entnehmen Sie den Test der Umverpackung. Bei Multitests Schutzkappe
abziehen. Kühl gelagerte Tests bzw. Urinproben vorher auf Raumtemperatur bringen.
2) Tauchen Sie die Streifen ca. 10-15 Sekunden in den Urin;
der Plastikrand darf den Urin nicht berühren.
3) Lesen Sie das Ergebnis nach ca. 5 Minuten ab.
Nach 10 Minuten keine Ergebnisse mehr auswerten.
3. Testauswertung
Im Reaktionsfeld befinden sich die Testzonen (T) der nachzuweisenden
Substanzen sowie eine Kontrollzone (C).
• Bei einem negativen Ergebnis, also einer drogen-freien Urinprobe, er
scheint ein pinkfarbener Streifen in der Testzone (T) und ein Streifen in
der Kontrollzone (C)
• Bei einem positiven Ergebnis ist nur noch ein Streifen in der
Kontrollzone (C) erkennbar.
Ist in der Kontrollregion (C) kein Streifen erkennbar, so ist z.B. nicht genügend
Urin aufgetragen worden und der Test ist ungültig!
Parameter*
Droge/Metabolit**
AMP
BAR
BZD
BUP
COC
COT
DOL
EDDP
EtG
FYL
KET
MDA
MDMA/XTC
MTD
MES
MET
MOR/OPI
MPD
MQL
OXY
PCP
PPX
PCM
Spice/K2
TCA
THC
Amphetamin
Secobarbital
Oxazepam
Buprenorphin-β3-D-Glucuronid
Benzoylecgonin
Cotinin
Pethidine
2-Ethylidin-1,5-Dimethyl-3,3Diphenylpyrrolidin
Ethylglucuronid
Fentanyl
Ketamin
Methylendioxyamphetamin
3,4-Methylendioxy-Metamphetamin
Methadon
Meskalin
Methamphetamin
Morphin
Methylphenidat
Methaqualon
Oxycodon
Phencyclidin
Norpropoxyphen
Paracetamol/Acetaminophen
JWH-073/JWH-018
Nortriptylin
11-nor-Δ9-THC-9-COOH
TML
TZD
ZAL
ZOL
Tramadol
Trazodon
Zaleplon
Zolpidem
verfügbare Cut-offs (ng/ml)
1000 / 500 / 300
300 / 200
300 / 200 / 100
10 / 5
600 / 300 / 200 / 100
1000 / 200
1000
100
500
10
1000
500
500
300 / 250
500
1000 / 500 / 300
2000 / 300 / 100
300
300
100
25
300
5000
50
1000 / 300
500 / 300 / 200 / 150 /
50 / 25
200 / 100
25
100
50
Einzeltest:
*auf den Test gedruckte Abkürzung
**Verbindung, die als Kalibrator zur Einstellung des jeweiligen Cut-Offs benutzt wurde.
Negativ
Positiv
Ungültig
Multitest:
AMP BZD COC MOR THC
AMP BZD COC MOR THC
Negativ für BZD+MOR
Ungültig
Positiv für AMP+COC+THC
Hinweis:
Die Farbintensität der Streifen auf der Testmembran kann bei den einzelnen
Parametern unterschiedlich sein. Nur wenn kein Streifen erscheint, ist der Test
positiv. Positive und unklare Resultate sollten mit einer zweiten analytischen
Methode bestätigt werden (z.B. GC/MS).
Buprenorphin wird ab einer Tagesdosis von 2 mg zuverlässig erfasst.
4. Warnungen und Vorsichtsmaßnahmen
• Nur für die in vitro Diagnose vorgesehen.
• Gebrauch nur für den Fachkreis bestimmt.
• Nach Ablauf des Verfalldatums den Test nicht mehr verwenden.
• Urinproben können infektiös sein. Deshalb werden saubere Handhabung
und sichere Aufbewahrung von verwendeten Teststreifen in geeigneten
Laborabfallbehältern empfohlen.
• Die Tests bei 2-30°C lagern und nicht einfrieren.
• Test bei beschädigter Schutzverpackung nicht mehr verwenden.
• Nach der Entnahme aus der Schutzverpackung Test sofort verwenden und
nicht auf die Saugfläche greifen.
1
• Nur zum Einmalgebrauch.
6.
Literatur
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
Aniline O., Pittes, F. N., Phencyclidine (PCP): A review and perspectives.
CRC Crit. Rev. Toxicol, 1982, 10, 145-177.
Baselt, R.C. Disposition of Toxic Drugs and Chemicals in Man. Biomedical
Publications, Davis, CA, 1982.
Thomas L. eds., Labor und Diagnose, 6. ed., TH-Books Verlagsgesellschaft,
Frankfurt, 2005
Urine Testing for Drugs of Abuse, National Institute on Drug. Abuse (NIDA),
Research Monograph 73, 1986.
Ellenhorn, M.J. and Barceloux, D.G. Medical Toxicology.
Elsevier Science Publishing Company, Inc., New York, 1988.
Fed. Register, Department of Health and Human Services, Mandatory Guidelines
for Federal Workplace Drug Testing Programs, 53, 69, 11970-11979, 1988.
Gilman, A. G., and Goodman, L. S. The Pharmacological Basis of Therapeutics,
eds. MacMillan Publishing, New York NY, 1980.
Gorodetzkym, C. W., Detection of Drugs of Abuse in Biological Fluids,
in Martin WR(ed): Drug Addiction I, New York, Spring-Verlag, 1977.
Greenblatt, D.J., Shader, R.I. Benzodiazepines in Clinical Practice.
New York: Raven Press, 1974.
Harvey, R.A., Champe, P.C. Lippincotts Illustrated Reviews. Pharmacology. 91-95, 1992.
Hofmann F.E., A Handbook on Drug and Alcohol Abuse: The Biomedical Aspects,
New York, Oxford University Press, 1983.
McBay, A. J., Clin. Chem. 33, 33B-40B, 1987
Drogenschnelltest-Gebrauchsanweisung | Dip / Multi-Dip
1.
Intended Use
English
5. Cut-offs
Single-sandwich immunoassays for qualitative determination of various drugs and
drug metabolites in human urine. The test should only to be used by medical
professionals.
2. Procedure of the Test
1) Remove the test from the packaging. Bring urine samples to room
temperature before performing the test.
2) Immerse the strip for approximately 10 to 15 seconds in the urine;
be sure that the edge of the plastic does not touch the urine.
3) Wait approximately 5 minutes before reading the results.
Do not evaluate results after 10 minutes, as they are no longer valid.
3. Interpretation of the Results
The test zone (T) detects drug substances found in the urine sample,
the remaining zone (C) is the control zone.
• With a negative result, and therefore a drug-free urine sample, a pink stripe
will appear in both the test zone (T) and in the control zone (C).
• With a positive result a pink stripe will only appear in the control zone (C).
If the control region (C) has no distinguishable line, not enough urine has
been applied and the test is invalid!
If the control region (C) has no distinguishable line, not enough urine has been
applied and the test is invalid!
Singletest:
Parameter*
Drug/Metabolite**
AMP
BAR
BZD
BUP
COC
COT
DOL
EDDP
EtG
FYL
KET
MDA
MDMA/XTC
MTD
MES
MET
MOR/OPI
MPD
MQL
OXY
PCP
PPX
PCM
Spice/K2
TCA
THC
Amphetamine
Secobarbital
Oxazepam
Buprenorphine-β3-D-Glucuronide
Benzoylecgonine
Cotinine
Pethidine
2-Ethylidine-1,5-Dimethyl-3,3Diphenylpyrrolidine
Ethyl glucuronide
Fentanyl
Ketamin
Methylendioxyamphetamine
3,4-Methylendioxy-Metamphetamine
Methadone
Mescaline
Methamphetamine
Morphine
Methylphenidate
Methaqualone
Oxycodone
Phencyclidine
Norpropoxyphene
Paracetamol/Acetaminophen
JWH-073/JWH-018
Nortriptyline
11-nor-Δ9-THC-9-COOH
TML
ZAL
ZOL
ZOL
Tramadol
Zaleplon
Zolpidem
Zolpidem
available Cut-offs (ng/ml)
1000 / 500 / 300
300 / 200
300 / 200 / 100
10 / 5
600 / 300 / 200 / 100
200
1000
100
500
10
1000
500
500
300 / 250
500
1000 / 500 / 300
2000 / 300 / 100
300
300
100
25
300
5000
50
1000 / 300
500 / 300 / 200 / 150 /
50 / 25
200 / 100
100
50
50
*Abbreviation printed on test
**Substance used for calibration the different cut-off levels.
Negative
Positive
Invalid
6.
Multitest:
AMP BZD COC MOR THC
AMP BZD COC MOR THC
Negative for BZD+MOR
Invalid
Positive for AMP+COC+THC
Note:
The intensity of the color stripe on the test field can vary depending on the
parameters that are being tested. It is only when no stripe appears that the
test is positive. Positive results should be confirmed by an additional testing
method (GC / MS).
Buprenorphine will start being detected at a daily dose of 2 mg.
Literatur
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
Aniline O., Pittes, F. N., Phencyclidine (PCP): A review and perspectives.
CRC Crit. Rev. Toxicol., 1982, 10, 145-177.
Baselt, R.C. Disposition of Toxic Drugs and Chemicals in Man. Biomedical
Publications, Davis, CA, 1982.
Thomas L. eds., Labor und Diagnose, 6. ed., TH-Books Verlagsgesellschaft, Frankfurt, 2005
Urine Testing for Drugs of Abuse, National Institute on Drug. Abuse (NIDA),
Research Monograph 73, 1986.
Ellenhorn, M.J. and Barceloux, D.G. Medical Toxicology.
Elsevier Science Publishing Company, Inc., New York, 1988.
Fed. Register, Department of Health and Human Services, Mandatory Guidelines for
Federal Workplace Drug Testing Programs, 53, 69, 11970-11979, 1988.
Gilman, A. G., and Goodman, L. S. The Pharmacological Basis of Therapeutics,
eds. MacMillan Publishing, New York NY, 1980.
Gorodetzkym, C. W., Detection of Drugs of Abuse in Biological Fluids,
in Martin WR(ed): Drug Addiction I, New York, Spring-Verlag, 1977.
Greenblatt, D.J., Shader, R.I. Benzodiazepines in Clinical Practice.
New York: Raven Press, 1974.
Harvey, R.A., Champe, P.C. Lippincotts Illustrated Reviews. Pharmacology. 91-95, 1992.
Hofmann F.E., A Handbook on Drug and Alcohol Abuse: The Biomedical Aspects,
New York, Oxford University Press, 1983.
McBay, A. J., Clin. Chem. 33, 33B-40B, 1987.
4. Warnings and Precautions
• For in vitro diagnostic use only.
• To be used by medical professionals only.
• After the expiry date, the test is no longer valid.
• Urine samples can be infectious. Therefore, clean handling and secure
storage of test strips is recommended.
• Store the tests between 2-30°C and be sure to not freeze the tests.
• Tests with damaged packaging should not be used.
• After removing the test from the protective packaging, the test should
be used immediately.
• For one time use only.
2
Drogenschnelltest-Gebrauchsanweisung | Dip / Multi-Dip
Français
1.
Domaine d’application
5. Cut-offs
Ce test utilise la méthode en Sandwich-Immunoassays pour la détection qualitative de drogues et de leurs métabolites dans les urines humaines. Le test est
uniquement prévu à un usage professionnel (milieux spécialisés).
2. Exécution du test
1) Retirer le test de son emballage. Les tests ainsi que les urines conservés au
frais doivent être amenés à température ambiante.
2) Tremper la bandelette dans l`urine pendant 15-30 secondes; la partie en
plastique ne doit pas entrer en contact avec l`urine3)
3) Lire les résultats après 5 minutes.
Ne pas interpreter les résultats après 10 minutes
3. Interprétation des résultats
Au niveau de la zone de réaction, se trouvent les zones de test (T) et les zones
de contrôle. (C).
• Pour un résultat négatif, donc réalisé sur un échantillon d’urine ne
contenant pas de drogue, une ligne de couleur rose apparaîtra dans la
zone de test (T) ainsi que dans la zone de contrôle (C).
• Pour un résultat positif, une seule ligne apparaît dans la zone
de contrôle (C).
Si aucune ligne n’apparaît dans la zone de contrôle (C), cela peut provenir
du fait qu’il n’y a pas assez d’urine. Le test est considéré comme non valide.
Einzeltest:
Paramètres*
Drogues/Métabolites**
AMP
BAR
BDZ
BUP
COC
COT
DOL
EDDP
EtG
FYL
KET
MDA
MDMA/XTC
MTD
MES
MET
MOR/OPI
MPD
MQL
OXY
PCP
PPX
PCM
Spice/K2
TCA
THC
Amphétamine
Sécobarbital
Oxazépam
Buprénorphine
Benzoylecgonine
Cotinine
Péthidine
2-Ethylidin-1,5-Dimethyl-3,3Diphenylpyrrolidin
Ethylglucuronide
Fentanyl
Kétamine
Methylendioxyamphétamine
3,4-Methylendioxy-Métamphétamine
Méthadone
Mescaline
Métamphétamine
Morphine
Méthylphénidate
Méthaqualone
Oxycodone
Phencyclidine
Norpropoxyphène
Paracétamol/Acétaminophène
JWH-073/JWH-018
Nortriptyline
11-nor-Δ9-THC-9-COOH
TML
TZD
ZAL
ZOL
Tramadol
Trazodon
Zaleplon
Zolpidem
Cut-off disponibles (ng/ml)
1000 / 500 / 300
300 / 200
300 / 200 / 100
10 / 5
600 / 300 / 200 / 100
1000 / 200
1000
100
500
10
1000
500
500
300 / 250
500
1000 / 500 / 300
2000 / 300 / 100
300
300
100
25
300
5000
50
1000 / 300
500 / 300 / 200 / 150 /
50 / 25
200 / 100
25
100
50
*Abréviation figurant sur le test
**Substance ayant été utilisée comme calibrateur pour le réglage des différents cut-offs.
Négatif
Positif
Non valide
6.
Multitest:
AMP BZD COC MOR THC
Négatif pour BZD+MOR
AMP BZD COC MOR THC
Non valide
Positif pour AMP+COC+THC
Indication:
L’intensité de la couleur de la bandelette sur la membrane du test peut être
différente selon les paramètres unitaires. Le test est positif seulement quand
aucune ligne n’apparaît. Les résultats positifs et douteux devront être confirmés par une deuxième méthode d’analyse (par exemple GC/MS).
La buprénorphine sera détectée à partir d’une dose journalière de 2mg.
4. Précautions et mesures de sécurité
• Réservé uniquement à une utilisation In-vitro
• Réservé à un usage professionnel.
• Ne pas utiliser au-delà de la date de péremption.
• Les échantillons d’urines doivent être considérés comme potentiellement
infectieux. Les manipuler et procéder à l’élimination selon les règles en vigueur.
• Conserver les tests à une température de 2-30°C et ne pas congeler.
• Ne pas utiliser le test si son emballage est endommagé.
• Utiliser immédiatement le test après ouverture de son emballage.
• Réservé à une utilisation unique.
3
Bibliographie
1) Aniline O., Pittes, F. N., Phencyclidine (PCP): A review and perspectives.
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
CRC Crit. Rev. Toxicol, 1982, 10, 145-177.
Baselt, R.C. Disposition of Toxic Drugs and Chemicals in Man. Biomedical Publications,
Davis, CA, 1982.
Thomas L. eds., Labor und Diagnose, 6. ed., TH-Books Verlagsgesellschaft, Frankfurt, 2005
Urine Testing for Drugs of Abuse, National Institute on Drug. Abuse (NIDA),
Research Monograph 73, 1986.
Ellenhorn, M.J. and Barceloux, D.G. Medical Toxicology. Elsevier Science Publishing
Company, Inc., New York, 1988.
Fed. Register, Department of Health and Human Services, Mandatory Guidelines for
Federal Workplace Drug Testing Programs, 53, 69, 11970-11979, 1988.
Gilman, A. G., and Goodman, L. S. The Pharmacological Basis of Therapeutics,
eds. MacMillan Publishing, New York NY, 1980.
Gorodetzkym, C. W., Detection of Drugs of Abuse in Biological Fluids, in Martin
WR(ed): Drug Addiction I, New York, Spring -Verlag, 1977.
Greenblatt, D.J., Shader, R.I. Benzodiazepines in Clinical Practice.
New York: Raven Press, 1974.
Harvey, R.A., Champe, P.C. Lippincotts Illustrated Reviews. Pharmacology. 91-95, 1992.
Hofmann F.E., A Handbook on Drug and Alcohol Abuse: The Biomedical Aspects,
New York, Oxford University Press, 1983.
McBay, A. J., Clin. Chem. 33, 33B-40B, 1987.
Drogenschnelltest-Gebrauchsanweisung | Dip / Multi-Dip
1.
Uso Previsto
Italiano
5. Cut-offs
Il single-sandwich immunoassays è un test qualitativo immunocromatografico per
rilevare rapidamente la presenza di diversi tipi di droghe d’abuso e dei loro metaboliti nell’urina umana. Il test è destinato unicamente ad uso professionale.
2. Procedura del Test
1) Rimuovere il test dall’involucro. Portare i campioni a temperatura ambiente
prima di effettuare il test.
2) Immergere la striscia nel campione di urina per 10-15 secondi. Fare in modo
che l’urina non venga a contatto con la finestra di controllo in plastica.
3) 3 Leggere I risultati dopo 5-10 minuti.
Non leggere il risultato dopo 10 minuti.
3. Interpretazione dei Risultati
La zona del test (T) rileva sostanze trovate nel campione d’urina e l’altra è la
zona di controllo.
• Con risultato negativo, appariranno una linea colorata (rosa) nella banda di
rilevazione del test (T) e una linea colorata nell’area di controllo (C).
• Con un risultato positivo è visibile una linea colorata solo nell’area
di controllo (C).
Se non appare nessuna banda nella zona di controllo, il test non è valido,
forse per un volume di urina insufficiente.
Singletest:
Parametro*
Droga/Metabolita**
AMP
BAR
BZD
BUP
COC
COT
DOL
EDDP
EtG
FYL
KET
MDA
MDMA/XTC
MTD
MES
MET
MOR/OPI
MPD
MQL
OXY
PCP
PPX
PCM
Spice/K2
TCA
THC
Amfetamina
Secobarbitolo
Oxazepam
Buprenorfina-ß3-D-Glucoronide
Benzoilecgonina
Cotinina
Petidina
2-Etilidina-1,5-Dimetil-3,3Definilpiralina
Etilglucoronide
Fentanyl
Chetamina
Metilendiossiamfetamina
3,4-Metilendiossimetanfetamina
Metadone
Mescalina
Metamfetamina
Morfina
Metilfenidato
Metaqualone
Ossicodone
Fenciclidina
Norpropossifene
Acetaminofene
JWH-073/JWH-018
Nortriptilina
11-nor-Δ9-THC-9-COOH
TML
TZD
ZAL
ZOL
Tramadolo
Trazodon
Zaleplon
Zolpidem
Cut-off disponibili (ng/ml)
1000 / 500 / 300
300 / 200
300 / 200 / 100
10 / 5
600 / 300 / 200 / 100
1000 / 200
1000
100
500
10
1000
500
500
300 / 250
500
1000 / 500 / 300
2000 / 300 / 100
300
300
100
25
300
5000
50
1000 / 300
500 / 300 / 200 / 150 /
50 / 25
200 / 100
25
100
50
*sigla stampata sul test
**sostanza utilizzata per la calibrazione dei rispettivi Cut-off.
Negativo
Positivo
Non valido
6.
Multitest:
AMP BZD COC MOR THC
AMP BZD COC MOR THC
Negativo per BZD+MOR
Non valido
Positivo per AMP+COC+THC
Note:
L’intensità del colore delle linee di test può variare per i diversi parametri. Il
test è considerato positivo solo se non compare la linea del test. I risultati
positivi e quelli non chiari devono essere ripetuti con un metodo analitico
alternativo (GC/MS).
La buprenorfina è rilevabile in modo attendibile con un dosaggio giornaliero
di 2 mg o superiore.
4. Avvertenze e precauzioni
Riferimenti Bibliografici
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)
12)
Aniline O., Pittes, F. N., Phencyclidine (PCP): A review and perspectives.
CRC Crit. Rev. Toxicol, 1982, 10, 145-177.
Baselt, R.C. Disposition of Toxic Drugs and Chemicals in Man.
Biomedical Publications, Davis, CA, 1982.
Thomas L. eds., Labor und Diagnose, 6. ed., TH-Books Verlagsgesellschaft, Frankfurt, 2005
Urine Testing for Drugs of Abuse, National Institute on Drug. Abuse (NIDA),
Research Monograph 73, 1986.
Ellenhorn, M.J. and Barceloux, D.G. Medical Toxicology.
Elsevier Science Publishing Company, Inc., New York, 1988.
Fed. Register, Department of Health and Human Services, Mandatory Guidelines for
Federal Workplace Drug Testing Programs, 53, 69, 11970-11979, 1988.
Gilman, A. G., and Goodman, L. S. The Pharmacological Basis of Therapeutics,
eds. MacMillan Publishing, New York NY, 1980.
Gorodetzkym, C. W., Detection of Drugs of Abuse in Biological Fluids,
in Martin WR(ed): Drug Addiction I, New York, Spring -Verlag, 1977.
Greenblatt, D.J., Shader, R.I. Benzodiazepines in Clinical Practice.
New York: Raven Press, 1974.
Harvey, R.A., Champe, P.C. Lippincotts Illustrated Reviews.
Pharmacology. 91-95, 1992.
Hofmann F.E., A Handbook on Drug and Alcohol Abuse: The Biomedical Aspects,
New York, Oxford University Press, 1983.
McBay, A. J., Clin. Chem. 33, 33B-40B, 1987
• Solo per uso in vitro.
• Solo per uso professionale.
• Non utilizzare dopo la data di scadenza.
• I campioni possono essere potenzialmente infetti. Manipolarli con le dovute
precauzioni e smaltirli in modo adeguato.
• Conservare e trasportare sempre a temperature comprese tra 2-30°C
e assicurarsi di non congelare i test.
• Non utilizzare il test se l’involucro è danneggiato.
• Utilizzare il test subito dopo aver aperto l’involucro.
• Monouso.
4
Drogenschnelltest-Gebrauchsanweisung | Dip / Multi-Dip
Detailed list of cut-offs
Alcohol
The urine alcohol test strip reacts with methyl, ethyl and allyl alcohol. The following
substances may interfere with test strips. Yet these substances do not normally
occur in sufficient quantities in human urine, in order to influence the test:
Ascorbic acid
L-methyl-dopa
Oxalic acid
Pyrogallol
Uric acid
Bilirubin
Methampyrone
Mercaptans
Peroxidase
Strong oxidizing agents tosylates
Tannic acid
L-Dopa
Amphetamine
Drug - Cut-off 1000 ng/ml
D-Amphetamine
L-Amphetamine
D-Methamphetamine
L-Methamphetamine
3,4-Methylenedioxyamphetamine (MDA)
3,4-Methylenedioxymethamphetamine (MDMA)
3,4-Methylenedioxy-N-ethylamphetamine (MDEA)
para-Methoxyamphetamine (PMA)
Concentration (ng/ml)
1.000
100.000
>20.000
>20.000
1.250
>20.000
>100.000
625
Drug - Cut-off 500 ng/ml
D-Amphetamine
L-Amphetamine
3,4-Methylenedioxyamphetamine (MDA)
3,4-Methylenedioxy-N-ethylamphetamine (MDEA)
Concentration (ng/ml)
500
15.000
700
12.000
Drug – Cut-off 300 ng/ml
D-Amphetamine
L-Amphetamine
3,4-Methylenedioxyamphetamine (MDA)
3,4-Methylenedioxy-N-ethylamphetamine (MDEA)
Concentration (ng/ml)
300
>50.000
500
>20.000
Barbiturate
Drug – Cut-off 300 ng/ml
Secobarbital
Phenobarbital
Butalbital
Allobarbital
Alphenal
Amobarbital
Aprobarbital
Hexobarbital
Butabarbital
Concentration (ng/ml)
300
300
3.000
5.000
625
600
600
>100.000
75
Drug – Cut-off 200 ng/ml
Secobarbital
Concentration (ng/ml)
200
Benzodiazepine
Drug – Cut-off 300 ng/ml
Oxazepam
OH-Alprazolam
Prazepam-d5
Nordiazepam
2OH-Ethylflurazepam
Diazepam
Trizolam
Lorazepam
Phenazepam
7-NH2-Clonazepam
Temazepam
7-NH2-Flunizepam
Bromazepam
Oxazepam-Gluc
a-OH-Midazolam
Nitrazepam
5
Concentration (ng/ml)
300
600
>30000
300
3000
240
480
600
750
>30000
90
>30000
420
330
>30000
>30000
Drug – Cut-off 200 ng/ml
Oxazepam
OH-Alprazelam
Prazepam-d5
Nor-Diazepam
2OH-Ethylflurazepam
Diazepam
Trizolam
Lorazepam
Phenazepam
7-NH2-Clonazepam
Temazepam
7-NH2-Flunizepam
Bromazepam
Oxazepam-Gluc
a-OH-Midazolam
Nitrazepam
Concentration (ng/ml)
200
400
>20000
200
2000
160
320
600
500
>20000
60
>20000
280
220
>20000
>20000
Drug – Cut-off 100 ng/ml
Oxazepam
OH-Alprazelam
Prazepam-d5
Nor-Diazepam
2OH-Ethylflurazepam
Diazepam
Trizolam
Lorazepam
Phenazepam
7-NH2-Clonazepam
Temazepam
7-NH2-Flunizepam
Bromazepam
Oxazepam-Gluc
a-OH-Midazolam
Nitrazepam
Concentration (ng/ml)
100
200
>10000
100
1000
80
160
200
250
>10000
30
>10000
140
110
>10000
>10000
Buprenorphine
Drug – Cut-off 10 ng/ml
Buprenorphine
Buprenorphine-3-β-d-glucunoride
Norbuprenorphine
Norbuprenorphine-3-β-d-glucunoride
Concentration (ng/ml)
10
10
12,5
500
Drug – Cut-off 5 ng/ml
Buprenorphine
Buprenorphine-3-β-d-glucunoride
Norbuprenorphine
Norbuprenorphine-3-β-d-glucunoride
Concentration (ng/ml)
5
5
6,25
250
Cocaine
Drug – Cut-off 300 ng/ml
Benzoylecgonin
Kokain
Ecgonin
Ecgonin-Methylester
Concentration (ng/ml)
300
1.000
>40.000
>100.000
Drug – Cut-off 200 ng/ml
Benzoylecgonine
Cocaine
Ecgonine
Ecgonin-Methylester
Concentration (ng/ml)
200
800
>40.000
>100.000
Drug – Cut-off 100 ng/ml
Benzoylecgonine
Cocaine
Ecgonine
Ecgonin-Methylester
Concentration (ng/ml)
100
300
>40.000
>100.000
Drogenschnelltest-Gebrauchsanweisung | Dip / Multi-Dip
Detailed list of cut-offs
Cotinine
Drug – Cut-off 200 ng/ml
Cotinin
(-)-Nikotin
Concentration (ng/ml)
200
>50.000
EDDP
Drug – Cut-off 100 ng/ml
2-Ethylidene-1,5-dimethyl-3,3diphenylpyrrolidine (EDDP)
Doxylamine
Methadone
Methadol
Concentration (ng/ml)
100
>1.000.000
>10.000
>10.000
Fentanyl
Drug – Cut-off 10 ng/ml
Fentanyl und Metabolite
Concentration (ng/ml)
10
Ketamine
Drug – Cut-off 1000 ng/ml
Ketamine
Norketamine
Phencyclidine
Dextromethorphan
Lidocaine
Promethazine
D-Amphetamine
Methadone
Methadol
Pethidine
Methampetamine
3,4-Methylenedioxymethamphetamine (MDMA)
Concentration (ng/ml)
1.000
2.000
>10.000
1.000
>100.000
20.000
>100.000
25.000
50.000
12.500
12.500
>100.000
MDA-Methylendioxyamphetamin
Drug – Cut-off 500 ng/ml
3,4-Methylenedioxyamphetamine (MDA)
3,4-Methylenedioxy-N-ethylamphetamine (MDEA)
Concentration (ng/ml)
500
300
MDMA-Methylendioxymethamphetamin
Drug - Cut-off 500 ng/ml
3,4-Methylenedioxymethamphetamine (MDMA)
3,4-Methylenedioxyamphetamine (MDA)
3,4-Methylenedioxy-N-ethylamphetamine (MDEA)
D-Amphetamine
D-Methamphetamine
para-Methoxyamphetamine (PMA)
Concentration (ng/ml)
500
1.000
300
>100.000
>100.000
5.000
Methadone
Drug – Cut-off 300 ng/ml
Methadone
Methadol
Dimenhydrinate
2-Ethylidene-1,5-dimethyl-3,3diphenylpyrrolidine (EDDP)
Doxylamine
Concentration (ng/ml)
300
1.000
2.500
>40.000
>40.000
Drug – Cut-off 500 ng/ml
D-Methamphetamine
D-Amphetamine
Chloroquine
(±)-Ephedrine
L-Methamphetamine
Mephentermin
3,4-Methylenedioxymethamphetamine (MDMA)
Procaine
β-Phenylethylamine
Ranitidine
Concentration (ng/ml)
500
>50.000
>50.000
>50.000
>50.000
>50.000
700
20.000
30.000
>50.000
Drug – Cut-off 300 ng/ml
D-Methamphetamine
D-Amphetamine
Chloroquine
(±)-Ephedrine
L-Methamphetamine
Mephentermine
3,4-Methylenedioxymethamphetamine (MDMA)
3,4-Methylenedioxy-N-ethylamphetamine
(MDEA)
Procaine
β-Phenylethylamine
Ranitidine
Concentration (ng/ml)
300
>40.000
5.000
>100.000
10.000
50.000
1.000
10.000
35.000
35.000
35.000
Methylphenidate
Drug – Cut-off 300 ng/ml
Methylphenindate
Ritalinic Acid
Konzentration (ng/ml)
300
25 000
Methaqualone
Drug – Cut-off 300 ng/ml
Methaqualone
Mecloqualone
3’-Hydroxymethaqualone
4’-Hydroxymethaqualone
2’-Hydroxymethaqualone
Amitriptyline
Carbamazepine
Nortriptyline
Phenytoine
Primidone
Theophylline
Konzentration (ng/ml)
300
500
500
500
3.000
50.000
20.000
50.000
40.000
24.000
40.000
Morphine/Opiates
Drug – Cut-off 2000 ng/ml
Morphine
Codeine
Diacetylmorphine (Heroin)
Ethylmorphi ne
Hydromorphone
Hydrocodone
Merperidine
6-Monoacetylmorphine
Morphine-3-β-d-glucuronide
Oxycodone
Oxymorphone
Rifampicin
Thebaine
Concentration (ng/ml)
2.000
2.000
2.000
600
15.000
15.000
>100.000
5.000
10.000
>20.000
>20.000
>50.000
20.000
Methamphetamine
Drug – Cut-off 1000 ng/ml
D-Methamphetamine
D-Amphetamine
Chloroquine
(+/-)-Ephedrine
L-Methamphetamine
3,4-Methylenedioxyamphetamine (MDA)
3,4-Methylenedioxymethamphetamine (MDMA)
3,4-Methylenedioxy-N-ethylamphetamine (MDEA)
Procaine
Concentration (ng/ml)
1.000
>40.000
10.000
>100.000
15.000
>10.000
2.000
20.000
100.000
6
Drogenschnelltest-Gebrauchsanweisung | Dip / Multi-Dip
Detailed list of cut-offs
Pethidine
Drug – Cut-off 1000 ng/ml
Pethidine
Drug – Cut-off 300 ng/ml
Morphine
Codeine
Diacetylmorphine (Heroin)
Ethylmorphine
Hydromorphone
Hydrocodone
Merperidine
6-Monoacetylmorphine
Morphine-3-β-d-glucuronide
Oxycodone
Oxymorphone
Promethazine
Rifampicin
Thebaine
Trimipramine
Concentration (ng/ml)
300
300
300
300
1.500
1.500
>100.000
300
6.000
>20.000
>20.000
>250.000
25.000
2.500
>20.000
Drug – Cut-off 200 ng/ml
Morphine
Codeine
Diacetylmorphine
Ethylmorphine
Hydromorphone
Hydrocodone
Meperidine
6-Monoacetylmorphine
Morphine-3-β-d-glucuronide
Oxycodone
Oxymorphone
Promethazine
Rifampicin
Thebaine
Trimipramine
Concentration (ng/ml)
200
200
200
200
1.000
1.000
>100.000
200
4.000
>20.000
>20.000
>250.000
16.600
1.700
>20.000
Drug – Cut-off 100 ng/ml
Morphine
Codeine
Diacetylmorphine
Ethylmorphine
Hydromorphone
Hydrocodone
Meperidine
6-Monoacetylmorphine
Morphine-3-β-d-glucuronide
Oxycodone
Oxymorphone
Promethazine
Rifampicin
Thebaine
Trimipramine
Concentration (ng/ml)
100
100
100
100
500
500
>100.000
100
2.000
>20.000
>20.000
>250.000
8.400
8.400
>20.000
Oxycodone
7
Phencyclidine
Drug – Cut-off 25 ng/ml
Phencyclidine
Tenocyclidine (TCP)
Concentration (ng/ml)
25
3.000
Paracetamol
Drug – Cut-off 5000 ng/ml
Paracetamol
Concentration (ng/ml)
5000
Propoxyphene
Drug – Cut-off 300 ng/ml
D-Propoxyphene
D-Norpropoxyphene
Concentration (ng/ml)
300
300
Spice/K2
Morphine
Drug – Cut-off 100 ng/ml
Oxycodone
Oxymorphone
Codeine
Diacetylmorphine (Heroine)
Ethylmorphine
Hydrocodone
Hydromorphone
Merperidine
6-Monoacetylmorphine
Morphine
Morphine-3-beta-D-glucuronide
Thebaine
Concentration (ng/ml)
1000
Concentration (ng/ml)
100
500
6.000
>100.000
10.000
10.000
10.000
>100.000
>100.000
>250.000
>100.000
>100.000
Drug – Cut-off 50 ng/ml
JWH 073
JWH 018 N-pentanoic acid
JWH 018 4-hydroxypentyl
JWH 018 N-(5-hydroxypentyl)
JWH 018 N-(5-hydroxypentyl)-ß-D-glucuro-nide
JWH 073 N-butyl acid
JWH 073 3-hydroxybutyl metabolite
JWH 122 N-pentanoic acid
JWH 122 N-(4-hydroxypentyl) metabolite
JWH 210 N-(5-carboxypentyl) metabolite
JWH 210 N-(4-hydroxypentyl) metabolite
JWH 250 N-(5-carboxypentyl) metabolite
JWH 019 N-(6-hydroxyhexyl) metabolite
JWH 081 N-(5-hydroxypentyl) metabolite
RCS-4 N-(4-hydroxypentyl) metabolite
JWH 398 N-(4-hydroxypentyl) metabolite
JWH 398 N-pentanoic acid
Concentration (ng/ml)
134
29
50
50
25
17
38
63
125
143
143
143
50
125
38
125
112
The following substances have a cross-reaction below 1%
with the Spice/K2 Test:
Substance
JWH018
JWH 122 N-(5-hydroxypentyl)
metabolite
JWH 250 N-(5-hydroxypentyl)
metabolite
XLR 11 N-(4-hydroxypentyl)
metabolite
Substance
UR-144 N-(5-hydroxypentyl) metabolite
RCS-4 N-(5-carboxypentyl)
metabolite
JWH 398 N-(5-hydroxypentyl)
metabolite
UR-144 N-pentanoic acid
Tricyclic Antidepressants
Drug – Cut-off 1000 ng/ml
Nortriptyline
Amitriptyline
Chlorpromazine
Clomipramine
Cyclobenzaprine
Desipramine
Diphenyldramine
Doxepin
Imipramin
Nordoxepin
Opipramol
Protriptylin
Perphenazin
Promazine
Promethazine
Protryptyline
Trimipramine
Concentration (ng/ml)
1.000
1.000
3.500
10.000
1.500
500
20.000
1.000
800
1.000
4.000
3.000
25.000
200
40.000
3.000
2.500
Drogenschnelltest-Gebrauchsanweisung | Dip / Multi-Dip
Detailed list of cut-offs
Drug – Cut-off 300 ng/ml
Nortriptyline
Amitriptyline
Chlorpromazine
Clomipramine
Cyclobenzaprine
Desipramine
Diphenyldramine
Doxepin
Imipramine
Nordoxepine
Opipramol
Protriptyline
Perphenazine
Promazine
Promethazine
Protryptyline
Trimipramine
Tramadol
Concentration (ng/ml)
300
300
1.100
3.300
500
125
7.000
300
200
300
1.250
1.000
7.000
70
12.500
1.000
800
THC (Marihuana)
Drug – Cut-off 500 ng/ml
11-nor-Δ8-THC-9-COOH
11-nor-Δ9-THC-9-COOH
Concentration (ng/ml)
500
500
Drug – Cut-off 300 ng/ml
11-nor-Δ8-THC-9-COOH
11-nor-Δ9-THC-9-COOH
Concentration (ng/ml)
300
300
Drug – Cut-off 200 ng/ml
11-nor-Δ8-THC-9-COOH
11-nor-Δ9-THC-9-COOH
11-Hydroxy-Δ9-Tetrahydrocannabinol
∆8-Tetrahydrocannabinol
∆9-Tetrahydrocannabinol
Cannabinol
Cannabidiol
Concentration (ng/ml)
200
200
>100.000
>80.000
>80.000
>20.000
>100.000
Drug – Cut-off 150 ng/ml
11-nor-Δ8-THC-9-COOH
11-nor-Δ9-THC-9-COOH
11-hydroxy-Δ9-Tetrahydrocannabinol
∆8-Tetrahydrocannabinol
∆9-Tetrahydrocannabinol
Cannabinol
Cannabidiol
Concentration (ng/ml)
150
150
>100.000
80.000
80.000
>20.000
>100.000
Drug – Cut-off 50 ng/ml
11-nor-Δ8-THC-9-COOH
11-nor-Δ9-THC-9-COOH
11-hydroxy-Δ9-Tetrahydrocannabinol
Δ8-Tetrahydrocannabinol
∆9-Tetrahydrocannabinol
Cannabinol
Cannabidiol
Concentration (ng/ml)
50
50
>100.000
15.000
15.000
20.000
>100.000
Drug – Cut-off 25 ng/ml
11-nor-Δ8-THC-9-COOH
11-nor-Δ9-THC-9-COOH
11-hydroxy-Δ9-Tetrahydrocannabinol
Δ8-Tetrahydrocannabinol
∆9-Tetrahydrocannabinol
Cannabinol
Cannabidiol
Concentration (ng/ml)
25
25
>100.000
10.000
10.000
15.000
>100.000
Drug – Cut-off 200 ng/ml
Tramadol
Concentration (ng/ml)
200
Drug – Cut-off 100 ng/ml
Tramadol
N-desmethyl-tramadol
O-desmethyl-tramadol
Concentration (ng/ml)
100
250
10.000
Trazodone
Drug – Cut-off 200 ng/ml
Trazodone
Trimipramine
Concentration (ng/ml)
25
25000
Zaleplon
Drug – Cut-off 100 ng/ml
Zaleplon
Concentration (ng/ml)
100
Zolpidem
Drug – Cut-off 50 ng/ml
Zolpidem
Concentration (ng/ml)
50
With exception of the respective parameters positive reacting drugs and drug
metabolites, which are listed above, all below listed compounds react negatively
up to a concentration of 100 µg/ml.
Acetaminophen
Acetone
Albumine
Ampicillin
Aspartam
Aspirin
Atropine
Benzocaine
ß-Phenylethylamine
Chinidine
Chloroquine
Chlorpheniramine
4-Dimethylaminoantipyrine
Dopamine (3-hydroxytyramine)
(-)-Ephedrine
(±)-Ephedrine
Ethanol
Furosemid
Guaiacol Glyceryl Ether
Hemoglobin
Ibuprofen
(±)-Isoproterenol
Coffein
Creatine
Lidocaine
L-Phenylephrin
N-Methyl-Ephedrin
(+)-Naproxen ((S)-6-methoxy-methyl-2-naphthaleneacetic acid)
Oxalic acid
Penicillin-G (Benzylpenicillin)
Pheniramine
Phenothiazine
Procaine
Ranitidine
Sulindac
Tyramine
Vitamin C (Ascorbic acid)
8
Drogenschnelltest-Gebrauchsanweisung | Dip / Multi-Dip
Contact
Stephany Diagnostika
Postfach 524
Bruggfeldweg 1
CH-4147 Aesch
Fon +41 (0)61 601 44 24
Fax +41 (0)61 601 44 25
[email protected]
www.stephany-diagnostika.ch
Rev. 1 /05.03.2015 / BS
Symbol
Deutsch
English
Français
Italiano
CE Konformitätszeichen
CE marking of conformity
Conformité aux normes
européennes
Conformità europea
Gebrauchsanweisung beachten
Consult instructions for use
Consulter la notice d’utilisation
Consultare le istruzioni per l’uso
In-vitro-Diagnostika
In-vitro diagnostic
Dispositif médical de diagnostic
in vitro
Dispoitivo medico-diagnostico
in vitro
Temperaturbegrenzung
Temperature limitation
Limites de température
Limiti di temperatura
Chargenbezeichnung
Batch code
Code du lot
Codice lotto
Nicht zur Wiederverwendung
Do not reuse
Ne pas réutiliser
Non riutilizzare
Verwendbar bis
Use by
Utiliser jusqu’au
Utilizzare entro
Bestellnummer
Catalogue Number
Référence du catalogue
Riferimento di Catalogo
Hersteller
Manufacturer
Fabricant
Fabbricante
Ausreichend für <n> Ansätze
Sufficient for <n> tests
Suffisant pour pour ”n” tests
Sufficiente per ”n” saggi

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