docESMO_valencia2016_intranet2 [Kompatibilitätsmodus]
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ESMO_valencia2016_intranet2 [Kompatibilitätsmodus]
Hospital Barmherzige Brueder Regensburg Department of General- and Visceral Surgery Salvage Surgery of Anal Canal Squamous carcinomas Pompiliu Piso Krankenhaus Barmherzige Brüder Regensburg Shridhar R et al, Cancer Journal for Clinicians 2015, 65(2):139-62 The locoregional recurrence rate after chemoradiation has ranged from 10 to 30% Patients who undergo salvage APR have 5 year survival rate of 40 to 60% 3 year survival rate of patients unsuitable for surgery is 5% Krankenhaus Barmherzige Brüder Regensburg Orsini et al, Eur J Cancer 2013 Krankenhaus Barmherzige Brüder Regensburg Krankenhaus Barmherzige Brüder Regensburg Photo: P. Piso Krankenhaus Barmherzige Brüder Regensburg Photo: P. Piso Krankenhaus Barmherzige Brüder Regensburg Krankenhaus Barmherzige Brüder Regensburg Schiller DE et al, Ann Surg Oncol 2007, 14(10):2780-9 Krankenhaus Barmherzige Brüder Regensburg Renehan AG et al, Br J Surg 2005,92(5):605-14 Krankenhaus Barmherzige Brüder Regensburg Mullen JT et al from MD Anderson, Ann Surg Oncol 2007, 14(2):478-83 Krankenhaus Barmherzige Brüder Regensburg Krankenhaus Barmherzige Brüder Regensburg Lefevre JH et al from Paris, Ann Surg Oncol 2012, 19(13):4186-92 105 Patients Krankenhaus Barmherzige Brüder Regensburg Correa JH et al from Brazil, J Surg Oncol 2013,107(5):486-92 Krankenhaus Barmherzige Brüder Regensburg Conclusions The local recurrence/persistent disease rate after initial treatment may be as high as 20% Surgical technique has improved, in particular the reconstruction method of the pelvic floor Postoperative morbidity is at present aceptable and the mortality low Achievment of a R0-resection is the most important prognostic factors Patients who undergo salvage resections have 5year survival rate of 40 to 60%
